The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological Functions

[EN] Artificial insemination (AI) is essential in intensive pig production, which significantly depends on semen quality from boars selected for health, genetics, and fertility. While AI aims to improve productivity, larger litters often result in smaller and less resistant piglets. Beyond fertility...

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Detalles Bibliográficos
Autores: Toledo Guardiola, Santa María, Luongo, Chiara, Martínez Pastor, Felipe, Soriano Úbeda, Cristina de las Mercedes, Matás, Carmen
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Universidad de León
Repositorio:BULERIA. Repositorio Institucional de la Universidad de León
OAI Identifier:oai:buleria.unileon.es:10612/26213
Acceso en línea:https://www.mdpi.com/2306-7381/12/6/582
https://hdl.handle.net/10612/26213
Access Level:acceso abierto
Palabra clave:Bioquímica
Fisiología
Genética
Veterinaria
Artificial insemination
High-fertility boars
Piglets
Production
Spermatozoa
Neonatal health
Glucose regulation
3104.11 Reproducción
2401.08 Genética Animal
3109 Ciencias Veterinarias
2401.13 Fisiología Animal
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oai_identifier_str oai:buleria.unileon.es:10612/26213
network_acronym_str ES
network_name_str España
repository_id_str
spelling The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological FunctionsToledo Guardiola, Santa MaríaLuongo, ChiaraMartínez Pastor, FelipeSoriano Úbeda, Cristina de las MercedesMatás, CarmenBioquímicaFisiologíaGenéticaVeterinariaArtificial inseminationHigh-fertility boarsPigletsProductionSpermatozoaNeonatal healthGlucose regulation3104.11 Reproducción2401.08 Genética Animal3109 Ciencias Veterinarias2401.13 Fisiología Animal[EN] Artificial insemination (AI) is essential in intensive pig production, which significantly depends on semen quality from boars selected for health, genetics, and fertility. While AI aims to improve productivity, larger litters often result in smaller and less resistant piglets. Beyond fertility and genetic traits, boars also influence offspring health. This study investigated the relationship between sperm parameters of highly fertile boars and both reproductive outcomes and piglet physiological indicators. Multivariate analysis revealed significant paternal effects on blood markers reflecting organ function, including those of the pancreas, liver, and kidneys, as well as on glucose homeostasis, lipid metabolism, oxidative stress, protein and carbohydrate metabolism, muscle contraction, and neural signaling. Notably, sperm velocity was correlated with mitochondrial function, which is crucial for sperm motility, capacitation, DNA integrity, and embryo development—factors likely linked to healthier, more resilient offspring. Boars transmitting superior sperm velocity, erythropoiesis efficiency, and oxygen transport capacities produced piglets with better glucose regulation, growth, and resistance to neonatal hypoglycemia. These findings underscore the broader impact of sperm quality on offspring vitality and suggest that advanced sperm analysis could improve boar selection and enable more effective, health-oriented breeding strategiesSIMDPIBiologia CelularFacultad de Ciencias Biologicas y Ambientales2025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://www.mdpi.com/2306-7381/12/6/582https://hdl.handle.net/10612/26213reponame:BULERIA. Repositorio Institucional de la Universidad de Leóninstname:Universidad de LeónInglésinfo:eu-repo/grantAgreement/AEI/ Programa Estatal de Generación de Conocimiento y Fortalecimiento Científico y Tecnológico del Sistema de I+D+i/ PID2019-106380RB-I00info:eu-repo/grantAgreement/AEI/Programa Estatal para Impulsar la Investigación Científico-Técnica y su Transferencia/PDC2022-133589-I00http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:buleria.unileon.es:10612/262132026-06-24T12:43:27Z
dc.title.none.fl_str_mv The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological Functions
title The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological Functions
spellingShingle The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological Functions
Toledo Guardiola, Santa María
Bioquímica
Fisiología
Genética
Veterinaria
Artificial insemination
High-fertility boars
Piglets
Production
Spermatozoa
Neonatal health
Glucose regulation
3104.11 Reproducción
2401.08 Genética Animal
3109 Ciencias Veterinarias
2401.13 Fisiología Animal
title_short The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological Functions
title_full The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological Functions
title_fullStr The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological Functions
title_full_unstemmed The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological Functions
title_sort The Individual Variations in Sperm Quality of High-Fertility Boars Impact the Offspring Production and Early Physiological Functions
dc.creator.none.fl_str_mv Toledo Guardiola, Santa María
Luongo, Chiara
Martínez Pastor, Felipe
Soriano Úbeda, Cristina de las Mercedes
Matás, Carmen
author Toledo Guardiola, Santa María
author_facet Toledo Guardiola, Santa María
Luongo, Chiara
Martínez Pastor, Felipe
Soriano Úbeda, Cristina de las Mercedes
Matás, Carmen
author_role author
author2 Luongo, Chiara
Martínez Pastor, Felipe
Soriano Úbeda, Cristina de las Mercedes
Matás, Carmen
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Biologia Celular
Facultad de Ciencias Biologicas y Ambientales
dc.subject.none.fl_str_mv Bioquímica
Fisiología
Genética
Veterinaria
Artificial insemination
High-fertility boars
Piglets
Production
Spermatozoa
Neonatal health
Glucose regulation
3104.11 Reproducción
2401.08 Genética Animal
3109 Ciencias Veterinarias
2401.13 Fisiología Animal
topic Bioquímica
Fisiología
Genética
Veterinaria
Artificial insemination
High-fertility boars
Piglets
Production
Spermatozoa
Neonatal health
Glucose regulation
3104.11 Reproducción
2401.08 Genética Animal
3109 Ciencias Veterinarias
2401.13 Fisiología Animal
description [EN] Artificial insemination (AI) is essential in intensive pig production, which significantly depends on semen quality from boars selected for health, genetics, and fertility. While AI aims to improve productivity, larger litters often result in smaller and less resistant piglets. Beyond fertility and genetic traits, boars also influence offspring health. This study investigated the relationship between sperm parameters of highly fertile boars and both reproductive outcomes and piglet physiological indicators. Multivariate analysis revealed significant paternal effects on blood markers reflecting organ function, including those of the pancreas, liver, and kidneys, as well as on glucose homeostasis, lipid metabolism, oxidative stress, protein and carbohydrate metabolism, muscle contraction, and neural signaling. Notably, sperm velocity was correlated with mitochondrial function, which is crucial for sperm motility, capacitation, DNA integrity, and embryo development—factors likely linked to healthier, more resilient offspring. Boars transmitting superior sperm velocity, erythropoiesis efficiency, and oxygen transport capacities produced piglets with better glucose regulation, growth, and resistance to neonatal hypoglycemia. These findings underscore the broader impact of sperm quality on offspring vitality and suggest that advanced sperm analysis could improve boar selection and enable more effective, health-oriented breeding strategies
publishDate 2025
dc.date.none.fl_str_mv 2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://www.mdpi.com/2306-7381/12/6/582
https://hdl.handle.net/10612/26213
url https://www.mdpi.com/2306-7381/12/6/582
https://hdl.handle.net/10612/26213
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/AEI/ Programa Estatal de Generación de Conocimiento y Fortalecimiento Científico y Tecnológico del Sistema de I+D+i/ PID2019-106380RB-I00
info:eu-repo/grantAgreement/AEI/Programa Estatal para Impulsar la Investigación Científico-Técnica y su Transferencia/PDC2022-133589-I00
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:BULERIA. Repositorio Institucional de la Universidad de León
instname:Universidad de León
instname_str Universidad de León
reponame_str BULERIA. Repositorio Institucional de la Universidad de León
collection BULERIA. Repositorio Institucional de la Universidad de León
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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