Visible-light mediated functionalization in Phe-containing peptides upon a debenzylative amination process

7 p.

Detalles Bibliográficos
Autores: Morales Ortega, Guillermo|||0009-0008-7786-2801, Pérez Cubero, Iván, Gómez-Bengoa, Enrique, Correa, Arkaitz, Carreras Pérez Aradros, Javier|||0000-0002-1521-6758
Tipo de recurso: artículo
Fecha de publicación:2026
País:España
Institución:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:dnet:ebuahbibliot::cfd120bf90ce07fd5fca820cd64dfa8e
Acceso en línea:http://hdl.handle.net/10017/68935
https://dx.doi.org/10.1002/adsc.70352
Access Level:acceso abierto
Palabra clave:Amination
Metal-free method
Peptides
Phenylalanine
Visible-light
Química
Chemistry
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spelling Visible-light mediated functionalization in Phe-containing peptides upon a debenzylative amination processMorales Ortega, Guillermo|||0009-0008-7786-2801Pérez Cubero, IvánGómez-Bengoa, EnriqueCorrea, ArkaitzCarreras Pérez Aradros, Javier|||0000-0002-1521-6758AminationMetal-free methodPeptidesPhenylalanineVisible-lightQuímicaChemistry7 p.An efficient protocol for the modification of phenylalanine-containing peptides is developed. The tandem debenzylation- amination process in N-terminal phenylalanine short peptides with N-iodoimides proceeds under visible-light irradiation and metal-free conditions. This method broadens the available chemical toolbox for the modification of Phe and allows the incorporation of N-containing heterocycles into peptide settings.Ministerio de Ciencia, Innovación y UniversidadesInstituto de Salud Carlos IIIUnión EuropeaGobierno VascoUniversidad de Alcalá20262026-03-17journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10017/68935https://dx.doi.org/10.1002/adsc.70352reponame:e_Buah Biblioteca Digital Universidad de Alcaláinstname:Universidad de Alcalá (UAH)InglésengMICIU Not available CNS2022-135208MICIU Not available PID2021-122889NBI00MICIU Not available RED2022-134074-TISCIII Not available RICORS2040ISCIII Not available RD24%2F0004%2F0008Gobierno Vasco http://dx.doi.org/10.13039/501100003086 Not available IT1741-22UAH Not available EPU-INV-UAH%2F2023%2F005open accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:dnet:ebuahbibliot::cfd120bf90ce07fd5fca820cd64dfa8e2026-06-18T11:13:07Z
dc.title.none.fl_str_mv Visible-light mediated functionalization in Phe-containing peptides upon a debenzylative amination process
title Visible-light mediated functionalization in Phe-containing peptides upon a debenzylative amination process
spellingShingle Visible-light mediated functionalization in Phe-containing peptides upon a debenzylative amination process
Morales Ortega, Guillermo|||0009-0008-7786-2801
Amination
Metal-free method
Peptides
Phenylalanine
Visible-light
Química
Chemistry
title_short Visible-light mediated functionalization in Phe-containing peptides upon a debenzylative amination process
title_full Visible-light mediated functionalization in Phe-containing peptides upon a debenzylative amination process
title_fullStr Visible-light mediated functionalization in Phe-containing peptides upon a debenzylative amination process
title_full_unstemmed Visible-light mediated functionalization in Phe-containing peptides upon a debenzylative amination process
title_sort Visible-light mediated functionalization in Phe-containing peptides upon a debenzylative amination process
dc.creator.none.fl_str_mv Morales Ortega, Guillermo|||0009-0008-7786-2801
Pérez Cubero, Iván
Gómez-Bengoa, Enrique
Correa, Arkaitz
Carreras Pérez Aradros, Javier|||0000-0002-1521-6758
author Morales Ortega, Guillermo|||0009-0008-7786-2801
author_facet Morales Ortega, Guillermo|||0009-0008-7786-2801
Pérez Cubero, Iván
Gómez-Bengoa, Enrique
Correa, Arkaitz
Carreras Pérez Aradros, Javier|||0000-0002-1521-6758
author_role author
author2 Pérez Cubero, Iván
Gómez-Bengoa, Enrique
Correa, Arkaitz
Carreras Pérez Aradros, Javier|||0000-0002-1521-6758
author2_role author
author
author
author
dc.subject.none.fl_str_mv Amination
Metal-free method
Peptides
Phenylalanine
Visible-light
Química
Chemistry
topic Amination
Metal-free method
Peptides
Phenylalanine
Visible-light
Química
Chemistry
description 7 p.
publishDate 2026
dc.date.none.fl_str_mv 2026
2026-03-17
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10017/68935
https://dx.doi.org/10.1002/adsc.70352
url http://hdl.handle.net/10017/68935
https://dx.doi.org/10.1002/adsc.70352
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv MICIU Not available CNS2022-135208
MICIU Not available PID2021-122889NBI00
MICIU Not available RED2022-134074-T
ISCIII Not available RICORS2040
ISCIII Not available RD24%2F0004%2F0008
Gobierno Vasco http://dx.doi.org/10.13039/501100003086 Not available IT1741-22
UAH Not available EPU-INV-UAH%2F2023%2F005
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:e_Buah Biblioteca Digital Universidad de Alcalá
instname:Universidad de Alcalá (UAH)
instname_str Universidad de Alcalá (UAH)
reponame_str e_Buah Biblioteca Digital Universidad de Alcalá
collection e_Buah Biblioteca Digital Universidad de Alcalá
repository.name.fl_str_mv
repository.mail.fl_str_mv
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