Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations?

Mumps outbreaks have recently been recorded in a number of highly vaccinated populations. We related seroprevalence, epidemiological and vaccination data from 18 European countries participating in The European Sero-Epidemiology Network (ESEN) to their risk of mumps outbreaks in order to inform vacc...

ver descrição completa

Detalhes bibliográficos
Autores: Eriksen, J, Davidkin, I, Kafatos, G, Andrews, N, Barbara, C, Cohen, D, Duks, A, Griškevičius, A, Johansen, K, Bartha, K, Kriz, B, Mitis, G, Mossong, J, Nardone, A, O'Flanagan, D, De Ory, Fernando de, Pistol, A, Theeten, H, Prosenc, K, Slacikova, M, Pebody, Richard
Formato: artículo
Fecha de publicación:2013
País:España
Recursos:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/11498
Acesso em linha:http://hdl.handle.net/20.500.12105/11498
Access Level:acceso abierto
Palavra-chave:Disease Outbreaks
Mumps Vaccine
Adolescent
Adult
Antibodies, Viral
Child
Child, Preschool
Europe
Female
Humans
Immunization Schedule
Incidence
Infant
Male
Middle Aged
Mumps
Mumps virus
Seroepidemiologic Studies
Vaccination
Young Adult
id ES_2eb78ab84f0f7e840006aabc43a930aa
oai_identifier_str oai:repisalud.isciii.es:20.500.12105/11498
network_acronym_str ES
network_name_str España
repository_id_str
spelling Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations?Eriksen, JDavidkin, IKafatos, GAndrews, NBarbara, CCohen, DDuks, AGriškevičius, AJohansen, KBartha, KKriz, BMitis, GMossong, JNardone, AO'Flanagan, DDe Ory, Fernando dePistol, ATheeten, HProsenc, KSlacikova, MPebody, RichardDisease OutbreaksMumps VaccineAdolescentAdultAntibodies, ViralChildChild, PreschoolEuropeFemaleHumansImmunization ScheduleIncidenceInfantMaleMiddle AgedMumpsMumps virusSeroepidemiologic StudiesVaccinationYoung AdultMumps outbreaks have recently been recorded in a number of highly vaccinated populations. We related seroprevalence, epidemiological and vaccination data from 18 European countries participating in The European Sero-Epidemiology Network (ESEN) to their risk of mumps outbreaks in order to inform vaccination strategies. Samples from national population serum banks were collected, tested for mumps IgG antibodies and standardized for international comparisons. A comparative analysis between countries was undertaken using age-specific mumps seroprevalence data and information on reported mumps incidence, vaccine strains, vaccination programmes and vaccine coverage 5-12 years after sera collection. Mean geometric mumps antibody titres were lower in mumps outbreak countries [odds ratio (OR) 0·09, 95% confidence interval (CI) 0·01-0·71)]. MMR1 vaccine coverage ⩾95% remained protective in a multivariable model (P < 0·001), as did an interval of 4-8 years between doses (OR 0·08, 95% CI 0·01-0·85). Preventing outbreaks and controlling mumps probably requires several elements, including high-coverage vaccination programmes with MMR vaccine with 4-8 years between doses.Cambridge University PressUnión Europea. Comisión Europea20202020-12-0420132013-03-0120132013-03-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://hdl.handle.net/20.500.12105/11498reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)InglésengEC QLK2-CT-2000-00542 Not availableopen accesshttp://purl.org/coar/access_right/c_abf2Atribución-NoComercial-CompartirIgual 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/114982026-06-12T12:43:37Z
dc.title.none.fl_str_mv Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations?
title Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations?
spellingShingle Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations?
Eriksen, J
Disease Outbreaks
Mumps Vaccine
Adolescent
Adult
Antibodies, Viral
Child
Child, Preschool
Europe
Female
Humans
Immunization Schedule
Incidence
Infant
Male
Middle Aged
Mumps
Mumps virus
Seroepidemiologic Studies
Vaccination
Young Adult
title_short Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations?
title_full Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations?
title_fullStr Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations?
title_full_unstemmed Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations?
title_sort Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations?
dc.creator.none.fl_str_mv Eriksen, J
Davidkin, I
Kafatos, G
Andrews, N
Barbara, C
Cohen, D
Duks, A
Griškevičius, A
Johansen, K
Bartha, K
Kriz, B
Mitis, G
Mossong, J
Nardone, A
O'Flanagan, D
De Ory, Fernando de
Pistol, A
Theeten, H
Prosenc, K
Slacikova, M
Pebody, Richard
author Eriksen, J
author_facet Eriksen, J
Davidkin, I
Kafatos, G
Andrews, N
Barbara, C
Cohen, D
Duks, A
Griškevičius, A
Johansen, K
Bartha, K
Kriz, B
Mitis, G
Mossong, J
Nardone, A
O'Flanagan, D
De Ory, Fernando de
Pistol, A
Theeten, H
Prosenc, K
Slacikova, M
Pebody, Richard
author_role author
author2 Davidkin, I
Kafatos, G
Andrews, N
Barbara, C
Cohen, D
Duks, A
Griškevičius, A
Johansen, K
Bartha, K
Kriz, B
Mitis, G
Mossong, J
Nardone, A
O'Flanagan, D
De Ory, Fernando de
Pistol, A
Theeten, H
Prosenc, K
Slacikova, M
Pebody, Richard
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Unión Europea. Comisión Europea
dc.subject.none.fl_str_mv Disease Outbreaks
Mumps Vaccine
Adolescent
Adult
Antibodies, Viral
Child
Child, Preschool
Europe
Female
Humans
Immunization Schedule
Incidence
Infant
Male
Middle Aged
Mumps
Mumps virus
Seroepidemiologic Studies
Vaccination
Young Adult
topic Disease Outbreaks
Mumps Vaccine
Adolescent
Adult
Antibodies, Viral
Child
Child, Preschool
Europe
Female
Humans
Immunization Schedule
Incidence
Infant
Male
Middle Aged
Mumps
Mumps virus
Seroepidemiologic Studies
Vaccination
Young Adult
description Mumps outbreaks have recently been recorded in a number of highly vaccinated populations. We related seroprevalence, epidemiological and vaccination data from 18 European countries participating in The European Sero-Epidemiology Network (ESEN) to their risk of mumps outbreaks in order to inform vaccination strategies. Samples from national population serum banks were collected, tested for mumps IgG antibodies and standardized for international comparisons. A comparative analysis between countries was undertaken using age-specific mumps seroprevalence data and information on reported mumps incidence, vaccine strains, vaccination programmes and vaccine coverage 5-12 years after sera collection. Mean geometric mumps antibody titres were lower in mumps outbreak countries [odds ratio (OR) 0·09, 95% confidence interval (CI) 0·01-0·71)]. MMR1 vaccine coverage ⩾95% remained protective in a multivariable model (P < 0·001), as did an interval of 4-8 years between doses (OR 0·08, 95% CI 0·01-0·85). Preventing outbreaks and controlling mumps probably requires several elements, including high-coverage vaccination programmes with MMR vaccine with 4-8 years between doses.
publishDate 2013
dc.date.none.fl_str_mv 2013
2013-03-01
2013
2013-03-01
2020
2020-12-04
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/11498
url http://hdl.handle.net/20.500.12105/11498
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv EC QLK2-CT-2000-00542 Not available
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución-NoComercial-CompartirIgual 4.0 Internacional
http://creativecommons.org/licenses/by-nc-sa/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución-NoComercial-CompartirIgual 4.0 Internacional
http://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Cambridge University Press
publisher.none.fl_str_mv Cambridge University Press
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869405429555003392
score 15,811543

Registos relacionados