Recent advances in nanoplasmonic biosensors

Motivated by the recent progress in the nanofabrication field and the increasing demand for cost-effective, portable, and easy-to-use point-of-care platforms, localized surface plasmon resonance (LSPR) biosensors have been subjected to a great scientific interest in the last few years. The progress...

Descripción completa

Detalles Bibliográficos
Autores: López Muñoz, Gerardo Arturo, Estévez, M. Carmen|||0000-0003-3694-7186, Soler Aznar, Maria|||0000-0001-7232-2277, Lechuga, Laura M|||0000-0001-5187-5358
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:195669
Acceso en línea:https://ddd.uab.cat/record/195669
https://dx.doi.org/urn:doi:10.1515/nanoph-2016-0101
Access Level:acceso abierto
Palabra clave:Bioanalytical applications
Cellphone technology
Clinical diagnostics
Integration
Lab-on-a-chip
Localized surface plasmon
Nanoplasmonics biosensors
Descripción
Sumario:Motivated by the recent progress in the nanofabrication field and the increasing demand for cost-effective, portable, and easy-to-use point-of-care platforms, localized surface plasmon resonance (LSPR) biosensors have been subjected to a great scientific interest in the last few years. The progress observed in the research of this nanoplasmonic technology is remarkable not only from a nanostructure fabrication point of view but also in the complete development and integration of operative devices and their application. The potential benefits that LSPR biosensors can offer, such as sensor miniaturization, multiplexing opportunities, and enhanced performances, have quickly positioned them as an interesting candidate in the design of lab-on-a-chip (LOC) optical biosensor platforms. This review covers specifically the most significant achievements that occurred in recent years towards the integration of this technology in compact devices, with views of obtaining LOC devices. We also discuss the most relevant examples of the use of the nanoplasmonic biosensors for real bioanalytical and clinical applications from assay development and validation to the identification of the implications, requirements, and challenges to be surpassed to achieve fully operative devices.