Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing

Captive breeding programmes represent the most intensive type of ex situ population management for threatened species. One example is the Cuvier’s gazelle programme that started in 1975 with only four founding individuals, and after more than four decades of management in captivity, a reintroduction...

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Authors: Alvarez-Estape, Marina, Fontseré Alemany, Clàudia, 1992-, Serres Armero, Aitor, 1992-, Kuderna, Lukas, 1989-, Dobrynin, Pavel, Guidara, Héla, Pukazhenthi, Budhan S., Koepfli, Klaus-Peter, Marquès i Bonet, Tomàs, 1975-, Moreno, Eulalia, Lizano González, Esther, 1974-
Format: article
Status:Published version
Publication Date:2022
Country:España
Institution:Universitat Pompeu Fabra
Repository:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/52678
Online Access:http://hdl.handle.net/10230/52678
http://dx.doi.org/10.1111/eva.13336
Access Level:Open access
Keyword:Captive breeding
Cuvier’s gazelle
Genomics
Inbreeding
Reintroduction
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spelling Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencingAlvarez-Estape, MarinaFontseré Alemany, Clàudia, 1992-Serres Armero, Aitor, 1992-Kuderna, Lukas, 1989-Dobrynin, PavelGuidara, HélaPukazhenthi, Budhan S.Koepfli, Klaus-PeterMarquès i Bonet, Tomàs, 1975-Moreno, EulaliaLizano González, Esther, 1974-Captive breedingCuvier’s gazelleGenomicsInbreedingReintroductionCaptive breeding programmes represent the most intensive type of ex situ population management for threatened species. One example is the Cuvier’s gazelle programme that started in 1975 with only four founding individuals, and after more than four decades of management in captivity, a reintroduction effort was undertaken in Tunisia in 2016, to establish a population in an area historically included within its range. Here, we aim to determine the genetic consequences of this reintroduction event by assessing the genetic diversity of the founder stock as well as of their descendants. We present the first whole-genome sequencing dataset of 30 Cuvier’s gazelles including captive-bred animals, animals born in Tunisia after a reintroduction and individuals from a genetically unrelated Moroccan population. Our analyses revealed no difference between the founder and the offspring cohorts in genome-wide heterozygosity and inbreeding levels, and in the amount and length of runs of homozygosity. The captive but unmanaged Moroccan gazelles have the lowest genetic diversity of all genomes analysed. Our findings demonstrate that the Cuvier’s gazelle captive breeding programme can serve as source populations for future reintroductions of this species. We believe that this study can serve as a starting point for global applications of genomics to the conservation plan of this species.T.M.-B. is supported by funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 864203), BFU2017-86471-P (MINECO/FEDER, UE), ‘Unidad de Excelencia María de Maeztu’, funded by the AEI (CEX2018-000792-M), Howard Hughes International Early Career and Secretaria d’Universitats i Recerca and CERCA Programme del Departament d’Economia i Coneixement de la Generalitat de Catalunya (GRC 2017 SGR 880). E.M. received financial support from the project PGC2018-097426-B-C22 (Spanish Ministry of Universities. Spanish State Research Agency. FEDER Program, European Union). E.L. is supported by CGL2017-82654-P (MINECO/FEDER, UE).Wiley202220222022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/52678http://dx.doi.org/10.1111/eva.13336reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésEvol Appl. 2022 Feb 22;15(3):351-64info:eu-repo/grantAgreement/EC/H2020/864203info:eu-repo/grantAgreement/ES/2PE/BFU2017-86471-Pinfo:eu-repo/grantAgreement/ES/2PE/CGL2017-82654-Pinfo:eu-repo/grantAgreement/ES/2PE/PGC2018-097426-B-C22© 2022 The Authors. Evolutionary Applications published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/526782026-06-12T07:21:37Z
dc.title.none.fl_str_mv Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
title Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
spellingShingle Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
Alvarez-Estape, Marina
Captive breeding
Cuvier’s gazelle
Genomics
Inbreeding
Reintroduction
title_short Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
title_full Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
title_fullStr Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
title_full_unstemmed Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
title_sort Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
dc.creator.none.fl_str_mv Alvarez-Estape, Marina
Fontseré Alemany, Clàudia, 1992-
Serres Armero, Aitor, 1992-
Kuderna, Lukas, 1989-
Dobrynin, Pavel
Guidara, Héla
Pukazhenthi, Budhan S.
Koepfli, Klaus-Peter
Marquès i Bonet, Tomàs, 1975-
Moreno, Eulalia
Lizano González, Esther, 1974-
author Alvarez-Estape, Marina
author_facet Alvarez-Estape, Marina
Fontseré Alemany, Clàudia, 1992-
Serres Armero, Aitor, 1992-
Kuderna, Lukas, 1989-
Dobrynin, Pavel
Guidara, Héla
Pukazhenthi, Budhan S.
Koepfli, Klaus-Peter
Marquès i Bonet, Tomàs, 1975-
Moreno, Eulalia
Lizano González, Esther, 1974-
author_role author
author2 Fontseré Alemany, Clàudia, 1992-
Serres Armero, Aitor, 1992-
Kuderna, Lukas, 1989-
Dobrynin, Pavel
Guidara, Héla
Pukazhenthi, Budhan S.
Koepfli, Klaus-Peter
Marquès i Bonet, Tomàs, 1975-
Moreno, Eulalia
Lizano González, Esther, 1974-
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Captive breeding
Cuvier’s gazelle
Genomics
Inbreeding
Reintroduction
topic Captive breeding
Cuvier’s gazelle
Genomics
Inbreeding
Reintroduction
description Captive breeding programmes represent the most intensive type of ex situ population management for threatened species. One example is the Cuvier’s gazelle programme that started in 1975 with only four founding individuals, and after more than four decades of management in captivity, a reintroduction effort was undertaken in Tunisia in 2016, to establish a population in an area historically included within its range. Here, we aim to determine the genetic consequences of this reintroduction event by assessing the genetic diversity of the founder stock as well as of their descendants. We present the first whole-genome sequencing dataset of 30 Cuvier’s gazelles including captive-bred animals, animals born in Tunisia after a reintroduction and individuals from a genetically unrelated Moroccan population. Our analyses revealed no difference between the founder and the offspring cohorts in genome-wide heterozygosity and inbreeding levels, and in the amount and length of runs of homozygosity. The captive but unmanaged Moroccan gazelles have the lowest genetic diversity of all genomes analysed. Our findings demonstrate that the Cuvier’s gazelle captive breeding programme can serve as source populations for future reintroductions of this species. We believe that this study can serve as a starting point for global applications of genomics to the conservation plan of this species.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/52678
http://dx.doi.org/10.1111/eva.13336
url http://hdl.handle.net/10230/52678
http://dx.doi.org/10.1111/eva.13336
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Evol Appl. 2022 Feb 22;15(3):351-64
info:eu-repo/grantAgreement/EC/H2020/864203
info:eu-repo/grantAgreement/ES/2PE/BFU2017-86471-P
info:eu-repo/grantAgreement/ES/2PE/CGL2017-82654-P
info:eu-repo/grantAgreement/ES/2PE/PGC2018-097426-B-C22
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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