Photochemistry of nabumetone in aqueous solution of sodium dodecyl sulfate (SDS) micelles

[EN]The photochemistry, solubility and distribution between two phases of nabumetone (NB) in aqueous solution of sodiumdodecyl sulfate (SDS) micelles were studied. The solubility (SNB) of NBwas monitored using steady-state UV–Vis absorption spectroscopy. The linear relationship of SNB to SDS concent...

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Detalles Bibliográficos
Autores: Valero Juan, Margarita, Levin, Peter P., Sultimova, Natalya B., Houston, Judith E.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:dnet:gredos______::207065c9138f302004c3bd51e83da281
Acceso en línea:http://hdl.handle.net/10366/170996
Access Level:acceso abierto
Palabra clave:Nabumetone
Sodium dodecyl sulfate (SDS)
Small angle neutron scattering (SANS)
Photochemistry
Fluorescence
Laser flash photolysis
fluorescencia
fotoquímica
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network_acronym_str ES
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spelling Photochemistry of nabumetone in aqueous solution of sodium dodecyl sulfate (SDS) micellesValero Juan, MargaritaLevin, Peter P.Sultimova, Natalya B.Houston, Judith E.NabumetoneSodium dodecyl sulfate (SDS)Small angle neutron scattering (SANS)PhotochemistryFluorescenceLaser flash photolysisPhotochemistryFluorescencefluorescenciafotoquímica[EN]The photochemistry, solubility and distribution between two phases of nabumetone (NB) in aqueous solution of sodiumdodecyl sulfate (SDS) micelles were studied. The solubility (SNB) of NBwas monitored using steady-state UV–Vis absorption spectroscopy. The linear relationship of SNB to SDS concentration ([SDS]) gave the large value of partition coefficient, P (logP= 3.5), for NB distribution between the aggregate and the water phase showing the localization of NB in the micellar phase. NB fluorescence (FL) quantumyield increaseswith [SDS] from0.03 in water to 0.056 at 0.2M[SDS]. The dependence of FL intensity at 355 nm(F335) on [SDS] is bell-shaped. The plot of initial F335 increase with [SDS] in the range 0–0.05Mgave the expected value of the critical micelle concentration (cmc = 7.9 mM). Further increase of [SDS] resulted in 10% decrease of F335 demonstrating the variation of the micellar structure. Small-Angle Neutron Scattering (SANS) and refractometry confirmed this variation. The NB in SDS was protected against photodegradation. High Performance Liquid Chromatography/Mass Spectrometry (HPLC/MS) detected 2-(but-2-en-1-yl)-6-methoxynaphthalene as NB final photoproducts in SDS solution which was not found in homogeneous media. The hydrated electron localized in water phase, NB radical cation and NB triplet excited state both localized in the micellar phase were observed by laser flash photolysis of NB in micellar solution. The decay kinetics of these intermediates was different with respect to that in the homogeneous media. The reactivity of NB in SDS micellar environment compared to the homogeneous media is under the discussion.Elsevier202620262020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10366/170996reponame:GREDOS. Repositorio Institucional de la Universidad de Salamancainstname:Universidad de Salamanca (USAL)InglésAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:dnet:gredos______::207065c9138f302004c3bd51e83da2812026-06-07T06:28:51Z
dc.title.none.fl_str_mv Photochemistry of nabumetone in aqueous solution of sodium dodecyl sulfate (SDS) micelles
title Photochemistry of nabumetone in aqueous solution of sodium dodecyl sulfate (SDS) micelles
spellingShingle Photochemistry of nabumetone in aqueous solution of sodium dodecyl sulfate (SDS) micelles
Valero Juan, Margarita
Nabumetone
Sodium dodecyl sulfate (SDS)
Small angle neutron scattering (SANS)
Photochemistry
Fluorescence
Laser flash photolysis
Photochemistry
Fluorescence
fluorescencia
fotoquímica
title_short Photochemistry of nabumetone in aqueous solution of sodium dodecyl sulfate (SDS) micelles
title_full Photochemistry of nabumetone in aqueous solution of sodium dodecyl sulfate (SDS) micelles
title_fullStr Photochemistry of nabumetone in aqueous solution of sodium dodecyl sulfate (SDS) micelles
title_full_unstemmed Photochemistry of nabumetone in aqueous solution of sodium dodecyl sulfate (SDS) micelles
title_sort Photochemistry of nabumetone in aqueous solution of sodium dodecyl sulfate (SDS) micelles
dc.creator.none.fl_str_mv Valero Juan, Margarita
Levin, Peter P.
Sultimova, Natalya B.
Houston, Judith E.
author Valero Juan, Margarita
author_facet Valero Juan, Margarita
Levin, Peter P.
Sultimova, Natalya B.
Houston, Judith E.
author_role author
author2 Levin, Peter P.
Sultimova, Natalya B.
Houston, Judith E.
author2_role author
author
author
dc.subject.none.fl_str_mv Nabumetone
Sodium dodecyl sulfate (SDS)
Small angle neutron scattering (SANS)
Photochemistry
Fluorescence
Laser flash photolysis
Photochemistry
Fluorescence
fluorescencia
fotoquímica
topic Nabumetone
Sodium dodecyl sulfate (SDS)
Small angle neutron scattering (SANS)
Photochemistry
Fluorescence
Laser flash photolysis
Photochemistry
Fluorescence
fluorescencia
fotoquímica
description [EN]The photochemistry, solubility and distribution between two phases of nabumetone (NB) in aqueous solution of sodiumdodecyl sulfate (SDS) micelles were studied. The solubility (SNB) of NBwas monitored using steady-state UV–Vis absorption spectroscopy. The linear relationship of SNB to SDS concentration ([SDS]) gave the large value of partition coefficient, P (logP= 3.5), for NB distribution between the aggregate and the water phase showing the localization of NB in the micellar phase. NB fluorescence (FL) quantumyield increaseswith [SDS] from0.03 in water to 0.056 at 0.2M[SDS]. The dependence of FL intensity at 355 nm(F335) on [SDS] is bell-shaped. The plot of initial F335 increase with [SDS] in the range 0–0.05Mgave the expected value of the critical micelle concentration (cmc = 7.9 mM). Further increase of [SDS] resulted in 10% decrease of F335 demonstrating the variation of the micellar structure. Small-Angle Neutron Scattering (SANS) and refractometry confirmed this variation. The NB in SDS was protected against photodegradation. High Performance Liquid Chromatography/Mass Spectrometry (HPLC/MS) detected 2-(but-2-en-1-yl)-6-methoxynaphthalene as NB final photoproducts in SDS solution which was not found in homogeneous media. The hydrated electron localized in water phase, NB radical cation and NB triplet excited state both localized in the micellar phase were observed by laser flash photolysis of NB in micellar solution. The decay kinetics of these intermediates was different with respect to that in the homogeneous media. The reactivity of NB in SDS micellar environment compared to the homogeneous media is under the discussion.
publishDate 2020
dc.date.none.fl_str_mv 2020
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10366/170996
url http://hdl.handle.net/10366/170996
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname:Universidad de Salamanca (USAL)
instname_str Universidad de Salamanca (USAL)
reponame_str GREDOS. Repositorio Institucional de la Universidad de Salamanca
collection GREDOS. Repositorio Institucional de la Universidad de Salamanca
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869405359996665856
score 15,811543

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