Insulin resistance risk assessed by TyG, METS-IR, and SPISE-IR scores and its association with sociodemographic and lifestyle factors in a large cohort of mechanics
[eng] Introduction: insulin resistance (IR) is a key metabolic disorder with significant implications for cardiovascular and hepatic health. While surrogate indices such as the triglyceride-glucose index (TyG), METS-IR, and SPISE-IR have been validated in various populations, their...
| Autores: | , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Universidad de las Islas Baleares |
| Repositorio: | Biblioteca Digital de les Illes Balears |
| OAI Identifier: | medicinaBalear:AJHS_Medicina_Balear_2025v40n6p078 |
| Acceso en línea: | http://ibdigital.uib.es/greenstone/sites/oai-site/collect/medicinaBalear/index/assoc/AJHS_Med/icina_Ba/lear_202/5v40n6p0/78.dir/AJHS_Medicina_Balear_2025v40n6p078.pdf http://ibdigital.uib.es/greenstone/library/collection/medicinaBalear/document/AJHS_Medicina_Balear_2025v40n6p078 |
| Access Level: | acceso abierto |
| Palabra clave: | Insulin resistance Health Sciences Medicine |
| Sumario: | [eng] Introduction: insulin resistance (IR) is a key metabolic disorder with significant implications for cardiovascular and hepatic health. While surrogate indices such as the triglyceride-glucose index (TyG), METS-IR, and SPISE-IR have been validated in various populations, their utility in physically demanding occupations remains underexplored. Objective: to assess IR risk using TyG, METS-IR, and SPISE-IR scores in a large cohort of automotive mechanics, and to examine associations with sociodemographic and lifestyle factors. Materials and method: a cross-sectional study was conducted among 39,120 mechanics (34,896 men; 4,224 women) aged 18–65 years across Spain. IR risk was estimated using TyG, METS-IR, and SPISE-IR indices based on fasting biochemical and anthropometric data. Logistic regression models evaluated associations with age, sex, education, smoking, physical activity, and adherence to the Mediterranean diet. Results: male workers exhibited significantly higher TyG and METS-IR scores and lower SPISE-IR values than females (p < 0.001). IR prevalence increased with age and was inversely associated with educational attainment. Smoking, low physical activity, and poor adherence to the Mediterranean diet were independently associated with elevated IR scores. Notably, SPISE-IR and METS-IR were more sensitive to lifestyle factors than TyG. Multivariate models confirmed sex, age, and lifestyle behaviors as strong predictors of IR risk. Conclusions: this study reveals a high burden of IR among automotive mechanics, particularly in older, male, and less-educated workers with unhealthy behaviors. The combined use of TyG, METS-IR, and SPISE-IR offers a robust framework for metabolic risk screening in occupational settings, supporting the need for targeted preventive strategies. |
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