Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints

Subjective memory complaints (SMCs) are a memory disorder that often precedes mild cognitive impairment (MCI) or Alzheimer’s disease (AD). Both individual alpha rhythms and cognitive reserve (CR) represent key features of SMCs and provide useful tools to characterize and predict the course of the di...

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Detalles Bibliográficos
Autores: Pérez, Vanesa, Hidalgo, Vanesa, Salvador, Alicia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Universidad de Zaragoza
Repositorio:Zaguán. Repositorio Digital de la Universidad de Zaragoza
OAI Identifier:oai:zaguan.unizar.es:136296
Acceso en línea:http://zaguan.unizar.es/record/136296
Access Level:acceso abierto
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spelling Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaintsPérez, VanesaHidalgo, VanesaSalvador, AliciaSubjective memory complaints (SMCs) are a memory disorder that often precedes mild cognitive impairment (MCI) or Alzheimer’s disease (AD). Both individual alpha rhythms and cognitive reserve (CR) represent key features of SMCs and provide useful tools to characterize and predict the course of the disorder. We studied whether older people with SMCs may also present some abnormal resting state electroencephalogram (rsEEG) alpha rhythms, and whether alpha rhythms are associated with CR. To do this, eyes-closed rsEEG were recorded in 68 older people with and without SMCs. The individual alpha indexes alpha/theta transition frequency (TF) and individual alpha frequency peak (IAFp) were computed. TF and IAFp were also used to determine the alpha1, alpha2, and alpha3 power frequency. Results indicated no differences in TF or IAFp between older people with SMCs and controls. The SMCs group showed a reduction in alpha3 power in comparison with controls. Specifically, women with SMCs were characterized by a significant decrease in alpha3 power compared to control women. Furthermore, only in SMCs group, greater CR was associated with slow IAFp. In sum, these results suggest that TF and IAFp are two stable indexes that are not influenced by the presence of SMCs. However, the reduction in alpha3, as observed in women with SMCs, shows an abnormal posterior rsEEG at alpha power. Finally, the compensatory mechanisms of CR appear to interact with the neurophysiological mechanisms that underlie the regulation of alpha rhythms.2024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://zaguan.unizar.es/record/136296reponame:Zaguán. Repositorio Digital de la Universidad de Zaragozainstname:Universidad de ZaragozaInglésInfo:eu-repo/grantAgreement/ES/AEI/PID2020-119406GB-I00info:eu-repo/grantAgreement/ES/DGA/S31-23Rinfo:eu-repo/semantics/openAccessoai:zaguan.unizar.es:1362962026-05-29T13:59:51Z
dc.title.none.fl_str_mv Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints
title Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints
spellingShingle Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints
Pérez, Vanesa
title_short Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints
title_full Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints
title_fullStr Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints
title_full_unstemmed Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints
title_sort Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints
dc.creator.none.fl_str_mv Pérez, Vanesa
Hidalgo, Vanesa
Salvador, Alicia
author Pérez, Vanesa
author_facet Pérez, Vanesa
Hidalgo, Vanesa
Salvador, Alicia
author_role author
author2 Hidalgo, Vanesa
Salvador, Alicia
author2_role author
author
description Subjective memory complaints (SMCs) are a memory disorder that often precedes mild cognitive impairment (MCI) or Alzheimer’s disease (AD). Both individual alpha rhythms and cognitive reserve (CR) represent key features of SMCs and provide useful tools to characterize and predict the course of the disorder. We studied whether older people with SMCs may also present some abnormal resting state electroencephalogram (rsEEG) alpha rhythms, and whether alpha rhythms are associated with CR. To do this, eyes-closed rsEEG were recorded in 68 older people with and without SMCs. The individual alpha indexes alpha/theta transition frequency (TF) and individual alpha frequency peak (IAFp) were computed. TF and IAFp were also used to determine the alpha1, alpha2, and alpha3 power frequency. Results indicated no differences in TF or IAFp between older people with SMCs and controls. The SMCs group showed a reduction in alpha3 power in comparison with controls. Specifically, women with SMCs were characterized by a significant decrease in alpha3 power compared to control women. Furthermore, only in SMCs group, greater CR was associated with slow IAFp. In sum, these results suggest that TF and IAFp are two stable indexes that are not influenced by the presence of SMCs. However, the reduction in alpha3, as observed in women with SMCs, shows an abnormal posterior rsEEG at alpha power. Finally, the compensatory mechanisms of CR appear to interact with the neurophysiological mechanisms that underlie the regulation of alpha rhythms.
publishDate 2024
dc.date.none.fl_str_mv 2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.none.fl_str_mv http://zaguan.unizar.es/record/136296
url http://zaguan.unizar.es/record/136296
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Info:eu-repo/grantAgreement/ES/AEI/PID2020-119406GB-I00
info:eu-repo/grantAgreement/ES/DGA/S31-23R
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.source.none.fl_str_mv reponame:Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname:Universidad de Zaragoza
instname_str Universidad de Zaragoza
reponame_str Zaguán. Repositorio Digital de la Universidad de Zaragoza
collection Zaguán. Repositorio Digital de la Universidad de Zaragoza
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