EndoCompass project: research roadmap for calcium and bone endocrinology
Background Endocrine science remains underrepresented in European Union research programmes despite the fundamental role of hormone health in human well-being. Analysis of the CORDIS database reveals a persistent gap between the societal impact of endocrine disorders and their research prioritizatio...
| Autores: | , , , , , , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Universidad Autónoma de Madrid |
| Repositorio: | Biblos-e Archivo. Repositorio Institucional de la UAM |
| Idioma: | inglés |
| OAI Identifier: | oai:dnet:biblosearchi::da85ee71d653d3edb957241d0511c7fd |
| Acceso en línea: | https://hdl.handle.net/10486/774380 https://dx.doi.org/10.1093/ejendo/lvaf064 |
| Access Level: | acceso abierto |
| Palabra clave: | calcium phosphate parathyroid hormone vitamin D bone primary hyperparathyroidism hypoparathyroidism Medicina |
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EndoCompass project: research roadmap for calcium and bone endocrinologyJähn-Rickert, KatharinaZibar Tomšic, KarinD. Anastasilakis, Athanasios D.Bertocchio, Jean-PhilippeBrandi, Maria LuisaFassnacht, MartinCheung, Moira Shang-MeiGevers, EvelienGittoes, NeilMartos Moreno, Gabriel ÁngelMilovanovic, PetarRaimann, AdalbertTencerova, MichaelaTsourdi, ElenaVlug, Annegreet G.Högler, WolfgangKamenický, Petercalciumphosphateparathyroid hormonevitamin Dboneprimary hyperparathyroidismhypoparathyroidismMedicinaBackground Endocrine science remains underrepresented in European Union research programmes despite the fundamental role of hormone health in human well-being. Analysis of the CORDIS database reveals a persistent gap between the societal impact of endocrine disorders and their research prioritization. At national funding level, endocrine societies report limited or little attention of national research funding towards endocrinology. The EndoCompass project—a joint initiative between the European Society of Endocrinology and the European Society of Paediatric Endocrinology—aimed to identify and promote strategic research priorities in endocrine science to address critical hormone-related health challenges. Methods Research priorities were established through comprehensive analysis of the EU CORDIS database covering the Horizon 2020 framework period (2014-2020). Expert consultation in bone and calcium endocrinology was conducted to identify key research priorities, followed by broader stakeholder engagement including society members and patient advocacy groups. Results Research priorities encompass primary hyperparathyroidism, chronic hypoparathyroidism, and rare calcium–phosphate disorders. Key areas include bone as endocrine organ, bone mass acquisition, secondary osteoporosis, and skeletal dysplasias. Special emphasis is placed on cellular senescence, sex-specific differences in disease manifestation, and development of novel diagnostic tools for bone quality assessment. Conclusions This component of the EndoCompass project provides an evidence-based roadmap for strategic research investment. This framework identifies crucial investigation areas into metabolic bone disease pathophysiology, prevention, and treatment strategies, ultimately aimed at reducing the burden of these disorders on individuals and society. The findings support the broader EndoCompass objective of aligning research funding with areas of highest potential impact in endocrine healthOxford University PressDepartamento de PediatríaFacultad de Medicina20252025-10-01review articlehttp://purl.org/coar/resource_type/c_dcae04bcAMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10486/774380https://dx.doi.org/10.1093/ejendo/lvaf06441104471reponame:Biblos-e Archivo. Repositorio Institucional de la UAMinstname:Universidad Autónoma de MadridInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:dnet:biblosearchi::da85ee71d653d3edb957241d0511c7fd2026-06-23T12:46:27Z |
| dc.title.none.fl_str_mv |
EndoCompass project: research roadmap for calcium and bone endocrinology |
| title |
EndoCompass project: research roadmap for calcium and bone endocrinology |
| spellingShingle |
EndoCompass project: research roadmap for calcium and bone endocrinology Jähn-Rickert, Katharina calcium phosphate parathyroid hormone vitamin D bone primary hyperparathyroidism hypoparathyroidism Medicina |
| title_short |
EndoCompass project: research roadmap for calcium and bone endocrinology |
| title_full |
EndoCompass project: research roadmap for calcium and bone endocrinology |
| title_fullStr |
EndoCompass project: research roadmap for calcium and bone endocrinology |
| title_full_unstemmed |
EndoCompass project: research roadmap for calcium and bone endocrinology |
| title_sort |
EndoCompass project: research roadmap for calcium and bone endocrinology |
| dc.creator.none.fl_str_mv |
Jähn-Rickert, Katharina Zibar Tomšic, Karin D. Anastasilakis, Athanasios D. Bertocchio, Jean-Philippe Brandi, Maria Luisa Fassnacht, Martin Cheung, Moira Shang-Mei Gevers, Evelien Gittoes, Neil Martos Moreno, Gabriel Ángel Milovanovic, Petar Raimann, Adalbert Tencerova, Michaela Tsourdi, Elena Vlug, Annegreet G. Högler, Wolfgang Kamenický, Peter |
| author |
Jähn-Rickert, Katharina |
| author_facet |
Jähn-Rickert, Katharina Zibar Tomšic, Karin D. Anastasilakis, Athanasios D. Bertocchio, Jean-Philippe Brandi, Maria Luisa Fassnacht, Martin Cheung, Moira Shang-Mei Gevers, Evelien Gittoes, Neil Martos Moreno, Gabriel Ángel Milovanovic, Petar Raimann, Adalbert Tencerova, Michaela Tsourdi, Elena Vlug, Annegreet G. Högler, Wolfgang Kamenický, Peter |
| author_role |
author |
| author2 |
Zibar Tomšic, Karin D. Anastasilakis, Athanasios D. Bertocchio, Jean-Philippe Brandi, Maria Luisa Fassnacht, Martin Cheung, Moira Shang-Mei Gevers, Evelien Gittoes, Neil Martos Moreno, Gabriel Ángel Milovanovic, Petar Raimann, Adalbert Tencerova, Michaela Tsourdi, Elena Vlug, Annegreet G. Högler, Wolfgang Kamenický, Peter |
| author2_role |
author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Departamento de Pediatría Facultad de Medicina |
| dc.subject.none.fl_str_mv |
calcium phosphate parathyroid hormone vitamin D bone primary hyperparathyroidism hypoparathyroidism Medicina |
| topic |
calcium phosphate parathyroid hormone vitamin D bone primary hyperparathyroidism hypoparathyroidism Medicina |
| description |
Background Endocrine science remains underrepresented in European Union research programmes despite the fundamental role of hormone health in human well-being. Analysis of the CORDIS database reveals a persistent gap between the societal impact of endocrine disorders and their research prioritization. At national funding level, endocrine societies report limited or little attention of national research funding towards endocrinology. The EndoCompass project—a joint initiative between the European Society of Endocrinology and the European Society of Paediatric Endocrinology—aimed to identify and promote strategic research priorities in endocrine science to address critical hormone-related health challenges. Methods Research priorities were established through comprehensive analysis of the EU CORDIS database covering the Horizon 2020 framework period (2014-2020). Expert consultation in bone and calcium endocrinology was conducted to identify key research priorities, followed by broader stakeholder engagement including society members and patient advocacy groups. Results Research priorities encompass primary hyperparathyroidism, chronic hypoparathyroidism, and rare calcium–phosphate disorders. Key areas include bone as endocrine organ, bone mass acquisition, secondary osteoporosis, and skeletal dysplasias. Special emphasis is placed on cellular senescence, sex-specific differences in disease manifestation, and development of novel diagnostic tools for bone quality assessment. Conclusions This component of the EndoCompass project provides an evidence-based roadmap for strategic research investment. This framework identifies crucial investigation areas into metabolic bone disease pathophysiology, prevention, and treatment strategies, ultimately aimed at reducing the burden of these disorders on individuals and society. The findings support the broader EndoCompass objective of aligning research funding with areas of highest potential impact in endocrine health |
| publishDate |
2025 |
| dc.date.none.fl_str_mv |
2025 2025-10-01 |
| dc.type.none.fl_str_mv |
review article http://purl.org/coar/resource_type/c_dcae04bc AM http://purl.org/coar/version/c_ab4af688f83e57aa |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
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article |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/10486/774380 https://dx.doi.org/10.1093/ejendo/lvaf064 41104471 |
| url |
https://hdl.handle.net/10486/774380 https://dx.doi.org/10.1093/ejendo/lvaf064 |
| identifier_str_mv |
41104471 |
| dc.language.none.fl_str_mv |
Inglés eng |
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Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
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Oxford University Press |
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Oxford University Press |
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reponame:Biblos-e Archivo. Repositorio Institucional de la UAM instname:Universidad Autónoma de Madrid |
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Universidad Autónoma de Madrid |
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Biblos-e Archivo. Repositorio Institucional de la UAM |
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Biblos-e Archivo. Repositorio Institucional de la UAM |
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