Socialization, and its modulation by sex, on the development and recovery of activity-based anorexia in rats

The activity-based anorexia (ABA) animal model has been used in the laboratory to study the role of excessive physical activity in the manifestation of anorexia nervosa (AN) in humans. Factors of social context are crucial in human health and the emergence of many psychological disorders, which have...

Descripción completa

Detalles Bibliográficos
Autores: Martínez Herrada, Antonio, Paz Regidor, Ana María de, Pellón Suárez de Puga, Ricardo
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad Nacional de Educación a Distancia
Repositorio:e-spacio. Repositorio Institucional de la UNED
Idioma:inglés
OAI Identifier:oai:e-spacio.uned.es:20.500.14468/12677
Acceso en línea:https://hdl.handle.net/20.500.14468/12677
Access Level:acceso abierto
Palabra clave:Anorexia nervosa
Activity-based anorexia
Socialization
Excessive activity
Sex differences
Recovery
Rats
id ES_2d1205bfc17fea780eaecb819967ab2c
oai_identifier_str oai:e-spacio.uned.es:20.500.14468/12677
network_acronym_str ES
network_name_str España
repository_id_str
spelling Socialization, and its modulation by sex, on the development and recovery of activity-based anorexia in ratsMartínez Herrada, AntonioPaz Regidor, Ana María dePellón Suárez de Puga, RicardoAnorexia nervosaActivity-based anorexiaSocializationExcessive activitySex differencesRecoveryRatsThe activity-based anorexia (ABA) animal model has been used in the laboratory to study the role of excessive physical activity in the manifestation of anorexia nervosa (AN) in humans. Factors of social context are crucial in human health and the emergence of many psychological disorders, which have also been observed in studies using different mammal species that, like human beings, set their lives in groups. In the present study, the animals’ social condition was manipulated to observe the effect of socialization in ABA development, and the possible different influence of the variable sex on the phenomenon. Eighty Wistar Han rats were distributed into four male and four female groups with 10 subjects each, manipulating social conditions (group housing or social isolation) and physical activity (access or not to a running wheel). Throughout the procedure, all groups had food restricted to 1 h/day during the light period. Furthermore, ABA experimental groups with access to the running wheel had two periods of access to the wheel of 2 h each, one before and the other after the food period. In this experiment, socialized rats were less vulnerable to weight loss during the procedure, although there were no differences between the ABA groups. Moreover, social enrichment was shown to be an enabling variable of the animals’ recovery after their withdrawal from the procedure, with this effect being more pronounced in females. The results in this study suggest the need to further in the analysis of the role of socialization in the development of ABA.Elseviere-Spacio UNED20242024-05-2020232023-07-1720232023-07-17journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14468/12677reponame:e-spacio. Repositorio Institucional de la UNEDinstname:Universidad Nacional de Educación a DistanciaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.esoai:e-spacio.uned.es:20.500.14468/126772026-06-06T12:38:31Z
dc.title.none.fl_str_mv Socialization, and its modulation by sex, on the development and recovery of activity-based anorexia in rats
title Socialization, and its modulation by sex, on the development and recovery of activity-based anorexia in rats
spellingShingle Socialization, and its modulation by sex, on the development and recovery of activity-based anorexia in rats
Martínez Herrada, Antonio
Anorexia nervosa
Activity-based anorexia
Socialization
Excessive activity
Sex differences
Recovery
Rats
title_short Socialization, and its modulation by sex, on the development and recovery of activity-based anorexia in rats
title_full Socialization, and its modulation by sex, on the development and recovery of activity-based anorexia in rats
title_fullStr Socialization, and its modulation by sex, on the development and recovery of activity-based anorexia in rats
title_full_unstemmed Socialization, and its modulation by sex, on the development and recovery of activity-based anorexia in rats
title_sort Socialization, and its modulation by sex, on the development and recovery of activity-based anorexia in rats
dc.creator.none.fl_str_mv Martínez Herrada, Antonio
Paz Regidor, Ana María de
Pellón Suárez de Puga, Ricardo
author Martínez Herrada, Antonio
author_facet Martínez Herrada, Antonio
Paz Regidor, Ana María de
Pellón Suárez de Puga, Ricardo
author_role author
author2 Paz Regidor, Ana María de
Pellón Suárez de Puga, Ricardo
author2_role author
author
dc.contributor.none.fl_str_mv e-Spacio UNED
dc.subject.none.fl_str_mv Anorexia nervosa
Activity-based anorexia
Socialization
Excessive activity
Sex differences
Recovery
Rats
topic Anorexia nervosa
Activity-based anorexia
Socialization
Excessive activity
Sex differences
Recovery
Rats
description The activity-based anorexia (ABA) animal model has been used in the laboratory to study the role of excessive physical activity in the manifestation of anorexia nervosa (AN) in humans. Factors of social context are crucial in human health and the emergence of many psychological disorders, which have also been observed in studies using different mammal species that, like human beings, set their lives in groups. In the present study, the animals’ social condition was manipulated to observe the effect of socialization in ABA development, and the possible different influence of the variable sex on the phenomenon. Eighty Wistar Han rats were distributed into four male and four female groups with 10 subjects each, manipulating social conditions (group housing or social isolation) and physical activity (access or not to a running wheel). Throughout the procedure, all groups had food restricted to 1 h/day during the light period. Furthermore, ABA experimental groups with access to the running wheel had two periods of access to the wheel of 2 h each, one before and the other after the food period. In this experiment, socialized rats were less vulnerable to weight loss during the procedure, although there were no differences between the ABA groups. Moreover, social enrichment was shown to be an enabling variable of the animals’ recovery after their withdrawal from the procedure, with this effect being more pronounced in females. The results in this study suggest the need to further in the analysis of the role of socialization in the development of ABA.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-07-17
2023
2023-07-17
2024
2024-05-20
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14468/12677
url https://hdl.handle.net/20.500.14468/12677
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:e-spacio. Repositorio Institucional de la UNED
instname:Universidad Nacional de Educación a Distancia
instname_str Universidad Nacional de Educación a Distancia
reponame_str e-spacio. Repositorio Institucional de la UNED
collection e-spacio. Repositorio Institucional de la UNED
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869405285370560512
score 15,812429

Similares en LA Referencia