Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study

Considering that the incidence of type 2 diabetes mellitus (T2DM) has been increasing especially in developing countries and becoming a global public health problem, this study aims to evaluate the association between triglyceride glucose index (TyG) – which is a mathematical product of the fasting...

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Autores: Balcells, Mercedes, De Oliveira, Camila Maciel, Pavani, Jessica, Liu, Chunyu, De Oliveira Alvim, Rafael, Mourao-Junior, Carlos Alberto, Krieger, José Eduardo, Da Costa Pereira, Alexandre
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Universitat Ramon Llull (URL)
Repositorio:DAU Arxiu Digital de la Universitat Ramon Llull
OAI Identifier:oai:dau.url.edu:20.500.14342/1058
Acceso en línea:http://hdl.handle.net/20.500.14342/1058
https://doi.org/10.1016/j.pmedr.2020.101172
Access Level:acceso abierto
Palabra clave:Glucosa
Diabetis
Cor--Malalties
Baependi Heart Study cohort
Triglyceride glucose index
Triglycerides
Glucose
Brazil
Type 2 diabetes mellitus
616.1
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repository_id_str
spelling Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart studyBalcells, MercedesDe Oliveira, Camila MacielPavani, JessicaLiu, ChunyuDe Oliveira Alvim, RafaelMourao-Junior, Carlos AlbertoKrieger, José EduardoDa Costa Pereira, AlexandreGlucosaDiabetisCor--MalaltiesBaependi Heart Study cohortTriglyceride glucose indexTriglyceridesGlucoseBrazilType 2 diabetes mellitus616.1Considering that the incidence of type 2 diabetes mellitus (T2DM) has been increasing especially in developing countries and becoming a global public health problem, this study aims to evaluate the association between triglyceride glucose index (TyG) – which is a mathematical product of the fasting blood glucose and triglyceride levels – and incident T2DM in an adult sample in the Baependi Heart Study (BHS). The data were from the BHS cohort consisting of two periods: cycle 1 (2005–2006; n = 1712; 119 families) and cycle 2 (2010–2013; n = 3017; 127 families). A total of 1121 individuals (both sexes, 18–100 years) were selected if they were assessed in both cycles and not diagnosed with T2DM at baseline (cycle 1). Our findings showed that a participant’s risk of developing T2DM increased almost 10 times for a one-unit increase in the TyG (odds ratio OR = 10.17, 95% CI, 7.51–13.93). The association when stratified by age was OR = 28.13 [95% CI, 14.03–56.41] for young adults, meaning that the risk of developing T2DM increased more than 28 times for a one-unit increase in the TyG. For the other groups, young middle-aged adults, old middle-aged adults, and seniors, we found OR = 4.84 [95% CI, 2.91–8.06], OR = 28.73 [95% CI, 10.63–77.65, and OR = 9.88 [95% CI, 3.16–30.90], respectively. A higher TyG implies a significant increase in the risk of developing T2DM, which could be an important screening tool to target early lifestyle intervention in Brazil.ElsevierUniversitat Ramon Llull. IQS20222023202220232020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion4 p.application/pdfhttp://hdl.handle.net/20.500.14342/1058https://doi.org/10.1016/j.pmedr.2020.101172RECERCAT (Dipòsit de la Recerca de Catalunya)reponame:DAU Arxiu Digital de la Universitat Ramon Llullinstname:Universitat Ramon Llull (URL)InglésPreventive medicine reports. Vol.20 (2020), 101172info:eu-repo/grantAgreement/SUS-PROADI/Hospital Samaritano Society/Grant no. 25000.180.664info:eu-repo/grantAgreement/MEIC/PN I+D/SAF2017-84773-C2-1-RAttribution-NonCommercial-NoDerivatives 4.0 International© L'autor/ahttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:dau.url.edu:20.500.14342/10582026-06-21T06:40:37Z
dc.title.none.fl_str_mv Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study
title Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study
spellingShingle Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study
Balcells, Mercedes
Glucosa
Diabetis
Cor--Malalties
Baependi Heart Study cohort
Triglyceride glucose index
Triglycerides
Glucose
Brazil
Type 2 diabetes mellitus
616.1
title_short Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study
title_full Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study
title_fullStr Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study
title_full_unstemmed Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study
title_sort Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study
dc.creator.none.fl_str_mv Balcells, Mercedes
De Oliveira, Camila Maciel
Pavani, Jessica
Liu, Chunyu
De Oliveira Alvim, Rafael
Mourao-Junior, Carlos Alberto
Krieger, José Eduardo
Da Costa Pereira, Alexandre
author Balcells, Mercedes
author_facet Balcells, Mercedes
De Oliveira, Camila Maciel
Pavani, Jessica
Liu, Chunyu
De Oliveira Alvim, Rafael
Mourao-Junior, Carlos Alberto
Krieger, José Eduardo
Da Costa Pereira, Alexandre
author_role author
author2 De Oliveira, Camila Maciel
Pavani, Jessica
Liu, Chunyu
De Oliveira Alvim, Rafael
Mourao-Junior, Carlos Alberto
Krieger, José Eduardo
Da Costa Pereira, Alexandre
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universitat Ramon Llull. IQS
dc.subject.none.fl_str_mv Glucosa
Diabetis
Cor--Malalties
Baependi Heart Study cohort
Triglyceride glucose index
Triglycerides
Glucose
Brazil
Type 2 diabetes mellitus
616.1
topic Glucosa
Diabetis
Cor--Malalties
Baependi Heart Study cohort
Triglyceride glucose index
Triglycerides
Glucose
Brazil
Type 2 diabetes mellitus
616.1
description Considering that the incidence of type 2 diabetes mellitus (T2DM) has been increasing especially in developing countries and becoming a global public health problem, this study aims to evaluate the association between triglyceride glucose index (TyG) – which is a mathematical product of the fasting blood glucose and triglyceride levels – and incident T2DM in an adult sample in the Baependi Heart Study (BHS). The data were from the BHS cohort consisting of two periods: cycle 1 (2005–2006; n = 1712; 119 families) and cycle 2 (2010–2013; n = 3017; 127 families). A total of 1121 individuals (both sexes, 18–100 years) were selected if they were assessed in both cycles and not diagnosed with T2DM at baseline (cycle 1). Our findings showed that a participant’s risk of developing T2DM increased almost 10 times for a one-unit increase in the TyG (odds ratio OR = 10.17, 95% CI, 7.51–13.93). The association when stratified by age was OR = 28.13 [95% CI, 14.03–56.41] for young adults, meaning that the risk of developing T2DM increased more than 28 times for a one-unit increase in the TyG. For the other groups, young middle-aged adults, old middle-aged adults, and seniors, we found OR = 4.84 [95% CI, 2.91–8.06], OR = 28.73 [95% CI, 10.63–77.65, and OR = 9.88 [95% CI, 3.16–30.90], respectively. A higher TyG implies a significant increase in the risk of developing T2DM, which could be an important screening tool to target early lifestyle intervention in Brazil.
publishDate 2020
dc.date.none.fl_str_mv 2020
2022
2022
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.14342/1058
https://doi.org/10.1016/j.pmedr.2020.101172
url http://hdl.handle.net/20.500.14342/1058
https://doi.org/10.1016/j.pmedr.2020.101172
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Preventive medicine reports. Vol.20 (2020), 101172
info:eu-repo/grantAgreement/SUS-PROADI/Hospital Samaritano Society/Grant no. 25000.180.664
info:eu-repo/grantAgreement/MEIC/PN I+D/SAF2017-84773-C2-1-R
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
© L'autor/a
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
© L'autor/a
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 4 p.
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv RECERCAT (Dipòsit de la Recerca de Catalunya)
reponame:DAU Arxiu Digital de la Universitat Ramon Llull
instname:Universitat Ramon Llull (URL)
instname_str Universitat Ramon Llull (URL)
reponame_str DAU Arxiu Digital de la Universitat Ramon Llull
collection DAU Arxiu Digital de la Universitat Ramon Llull
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.300719

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