Influence of adherence to the mediterranean diet on vascular health and healthy aging in women: assessment using CAVI

Background: Vascular aging, characterized by a progressive increase in arterial stiffness, is associated with an increased risk of cardiovascular disease. The Mediterranean diet (MD) has been shown to have protective effects on cardiovascular health, but its relationship with vascular aging, as asse...

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Autores: Llamas Ramos, Inés, Llamas Ramos, Rocío, Cortés Rodríguez, María, Rodríguez Sánchez, Emiliano, Gómez-Marcos, Manuel A., Gómez Sánchez, Marta, Gómez Sánchez, Leticia
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Recursos:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/167439
Acesso em linha:http://hdl.handle.net/10366/167439
Access Level:acceso embargado
Palavra-chave:Vascular aging
Envejecimiento vascular
Arterial stiffness
Rigidez arterial
CAVI
Mediterranean diet
Cardiovascular risk
Riesgo cardiovascular
Lifestyle
Estilo de vida
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repository_id_str
spelling Influence of adherence to the mediterranean diet on vascular health and healthy aging in women: assessment using CAVILlamas Ramos, InésLlamas Ramos, RocíoCortés Rodríguez, MaríaRodríguez Sánchez, EmilianoGómez-Marcos, Manuel A.Gómez Sánchez, MartaGómez Sánchez, LeticiaVascular agingEnvejecimiento vascularArterial stiffnessRigidez arterialCAVIMediterranean dietCardiovascular riskRiesgo cardiovascularLifestyleEstilo de vidaBackground: Vascular aging, characterized by a progressive increase in arterial stiffness, is associated with an increased risk of cardiovascular disease. The Mediterranean diet (MD) has been shown to have protective effects on cardiovascular health, but its relationship with vascular aging, as assessed by the Cardio-Ankle Vascular Index (CAVI), is not yet well established. Objective: To analyze the association between adherence to the MD and vascular aging estimated with CAVI in a sample of Spanish women with no history of previous cardiovascular disease. Methods: A cross-sectional study was conducted in 1468 women (aged 30–80 years), classified into three categories according to CAVI: healthy vascular aging (HVA), normal (NVA), and early (EVA). Adherence to the MD was assessed using the MEDAS questionnaire validated in Spain. ANOVA and chi-square tests were used to compare baseline characteristics, and multinomial logistic regression was used to analyze the association between MD adherence and vascular aging status, adjusting for age, sex, and drug treatment. Results: The CAVI increased progressively with age (p < 0.001) and was associated with higher blood pressure, dyslipidemia, hyperglycemia, and diabetes mellitus. Adherence to the MD was significantly higher in groups with lower arterial stiffness (p < 0.001). In the multivariate analysis, greater adherence to MD was associated with a higher probability of healthy vascular aging compared to NVA (OR: 1.872; 95% CI: 1.366–2.566; p < 0.001) and EVA (OR: 1.738; 95% CI: 1.363–2.218; p < 0.001). Conclusions: Greater adherence to the MD is associated with a healthier vascular aging profile. Promoting this dietary pattern may be an effective strategy for preventing arterial stiffness and reducing the cardiovascular risk associated with aging.https://www.mdpi.com/2072-6643/17/18/2963info202520252025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10366/167439reponame:GREDOS. Repositorio Institucional de la Universidad de Salamancainstname:Universidad de Salamanca (USAL)InglésAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/embargoedAccessoai:gredos.usal.es:10366/1674392026-06-07T06:28:51Z
dc.title.none.fl_str_mv Influence of adherence to the mediterranean diet on vascular health and healthy aging in women: assessment using CAVI
title Influence of adherence to the mediterranean diet on vascular health and healthy aging in women: assessment using CAVI
spellingShingle Influence of adherence to the mediterranean diet on vascular health and healthy aging in women: assessment using CAVI
Llamas Ramos, Inés
Vascular aging
Envejecimiento vascular
Arterial stiffness
Rigidez arterial
CAVI
Mediterranean diet
Cardiovascular risk
Riesgo cardiovascular
Lifestyle
Estilo de vida
title_short Influence of adherence to the mediterranean diet on vascular health and healthy aging in women: assessment using CAVI
title_full Influence of adherence to the mediterranean diet on vascular health and healthy aging in women: assessment using CAVI
title_fullStr Influence of adherence to the mediterranean diet on vascular health and healthy aging in women: assessment using CAVI
title_full_unstemmed Influence of adherence to the mediterranean diet on vascular health and healthy aging in women: assessment using CAVI
title_sort Influence of adherence to the mediterranean diet on vascular health and healthy aging in women: assessment using CAVI
dc.creator.none.fl_str_mv Llamas Ramos, Inés
Llamas Ramos, Rocío
Cortés Rodríguez, María
Rodríguez Sánchez, Emiliano
Gómez-Marcos, Manuel A.
Gómez Sánchez, Marta
Gómez Sánchez, Leticia
author Llamas Ramos, Inés
author_facet Llamas Ramos, Inés
Llamas Ramos, Rocío
Cortés Rodríguez, María
Rodríguez Sánchez, Emiliano
Gómez-Marcos, Manuel A.
Gómez Sánchez, Marta
Gómez Sánchez, Leticia
author_role author
author2 Llamas Ramos, Rocío
Cortés Rodríguez, María
Rodríguez Sánchez, Emiliano
Gómez-Marcos, Manuel A.
Gómez Sánchez, Marta
Gómez Sánchez, Leticia
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Vascular aging
Envejecimiento vascular
Arterial stiffness
Rigidez arterial
CAVI
Mediterranean diet
Cardiovascular risk
Riesgo cardiovascular
Lifestyle
Estilo de vida
topic Vascular aging
Envejecimiento vascular
Arterial stiffness
Rigidez arterial
CAVI
Mediterranean diet
Cardiovascular risk
Riesgo cardiovascular
Lifestyle
Estilo de vida
description Background: Vascular aging, characterized by a progressive increase in arterial stiffness, is associated with an increased risk of cardiovascular disease. The Mediterranean diet (MD) has been shown to have protective effects on cardiovascular health, but its relationship with vascular aging, as assessed by the Cardio-Ankle Vascular Index (CAVI), is not yet well established. Objective: To analyze the association between adherence to the MD and vascular aging estimated with CAVI in a sample of Spanish women with no history of previous cardiovascular disease. Methods: A cross-sectional study was conducted in 1468 women (aged 30–80 years), classified into three categories according to CAVI: healthy vascular aging (HVA), normal (NVA), and early (EVA). Adherence to the MD was assessed using the MEDAS questionnaire validated in Spain. ANOVA and chi-square tests were used to compare baseline characteristics, and multinomial logistic regression was used to analyze the association between MD adherence and vascular aging status, adjusting for age, sex, and drug treatment. Results: The CAVI increased progressively with age (p < 0.001) and was associated with higher blood pressure, dyslipidemia, hyperglycemia, and diabetes mellitus. Adherence to the MD was significantly higher in groups with lower arterial stiffness (p < 0.001). In the multivariate analysis, greater adherence to MD was associated with a higher probability of healthy vascular aging compared to NVA (OR: 1.872; 95% CI: 1.366–2.566; p < 0.001) and EVA (OR: 1.738; 95% CI: 1.363–2.218; p < 0.001). Conclusions: Greater adherence to the MD is associated with a healthier vascular aging profile. Promoting this dietary pattern may be an effective strategy for preventing arterial stiffness and reducing the cardiovascular risk associated with aging.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025
2025
info
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10366/167439
url http://hdl.handle.net/10366/167439
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/embargoedAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv embargoedAccess
dc.publisher.none.fl_str_mv https://www.mdpi.com/2072-6643/17/18/2963
publisher.none.fl_str_mv https://www.mdpi.com/2072-6643/17/18/2963
dc.source.none.fl_str_mv reponame:GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname:Universidad de Salamanca (USAL)
instname_str Universidad de Salamanca (USAL)
reponame_str GREDOS. Repositorio Institucional de la Universidad de Salamanca
collection GREDOS. Repositorio Institucional de la Universidad de Salamanca
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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