Prematurity and ADHD in childhood: an observational register-based study in Catalonia

Objective: To evaluate the association between prematurity (by the gestational week [gw]) and ADHD during childhood. Method: Observational, matched cohort study using data from children born in a tertiary-level hospital (Hospital Universitari Vall d'Hebron, Catalonia, Spain) during 1995-2007 an...

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Detalles Bibliográficos
Autores: Perapoch, Josep, Vidal, Raquel, Gómez Lumbreras, Ainhoa, Hermosilla, Eduardo, Riera, Lidia, Cortés Martínez, Jordi|||0000-0002-3764-0795, Céspedes, Maria Concepció, Ramos Quiroga, Josep Antoni, Morros Padrós, Rosa
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/175661
Acceso en línea:https://hdl.handle.net/2117/175661
https://dx.doi.org/10.1177/1087054719864631
Access Level:acceso abierto
Palabra clave:Biomathematics
Sampling (Statistics)
Biomatemàtica
Mostreig (Estadística)
Classificació AMS::92 Biology and other natural sciences::92B Mathematical biology in general
Classificació AMS::62 Statistics::62D05 Sampling theory, sample surveys
Àrees temàtiques de la UPC::Matemàtiques i estadística::Matemàtica aplicada a les ciències
Àrees temàtiques de la UPC::Matemàtiques i estadística::Estadística aplicada::Estadística biosanitària
Descripción
Sumario:Objective: To evaluate the association between prematurity (by the gestational week [gw]) and ADHD during childhood. Method: Observational, matched cohort study using data from children born in a tertiary-level hospital (Hospital Universitari Vall d'Hebron, Catalonia, Spain) during 1995-2007 and data from the Information System for the Development of Research in Primary Health Care (SIDIAP database, Catalonia, Spain). Results: Prevalence of ADHD increases as gestational age decreases, 12.7% for those born =28 gw, compared to 3.2% for those born after the 37 gw. The risk of developing ADHD in the non-premature children tends to increase as the gw decreases (35-36 gw, hazard ratio [HR] = 1.70, 95% confidence interval [CI] [1.19, 2.44]; 33-34 gw, HR = 3.38, 95% CI [2.08, 5.50]; 29-32 gw, HR = 2.37, 95% CI [1.54, 3.63]; and =28 gw, HR = 5.57, 95% CI [2.49, 12.46]) Conclusion: Being born preterm is associated with a risk of developing ADHD, also in late preterm children (35-36 gw). Attention when taking care of these infants regarding their mental health must be made.