Prostatic artery embolization versus transurethral resection of the prostate: a post hoc cost analysis of a randomized controlled clinical trial

Purpose: To perform a post hoc analysis of patient-incurred costs in a randomized controlled clinical trial comparing prostatic artery embolization (PAE) and transurethral resection of the prostate (TURP). Materials and methods: Patients older than 60 years with indication of TURP were randomized to...

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Autores: Capdevila, F. (Ferrán)|||/items/93ed5405-dd06-40e7-a6f4-9a236c191a92, Insausti-Gorbea, I. (Iñigo)|||/items/8b0a63e0-ccf3-484c-a43f-7bb5847e4ac1, Galbete, A. (Arkaitz)|||/items/ec7b27ee-75e0-40a0-a8ac-993c7832c433, Sanchez-Iriso, E. (Eduardo)|||/items/af410c06-9878-408f-b451-de312bf73886, Montesino, M. (Manuel)|||/items/21d2fa34-149d-43a5-bbd4-b0fe81aceb71
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/111024
Acceso en línea:https://hdl.handle.net/10171/111024
Access Level:acceso abierto
Palabra clave:Prostatic artery embolization (PAE)
Transurethral resection of the prostate (TURP)
Costs
Benign prostatic hyperplasia
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spelling Prostatic artery embolization versus transurethral resection of the prostate: a post hoc cost analysis of a randomized controlled clinical trialCapdevila, F. (Ferrán)|||/items/93ed5405-dd06-40e7-a6f4-9a236c191a92Insausti-Gorbea, I. (Iñigo)|||/items/8b0a63e0-ccf3-484c-a43f-7bb5847e4ac1Galbete, A. (Arkaitz)|||/items/ec7b27ee-75e0-40a0-a8ac-993c7832c433Sanchez-Iriso, E. (Eduardo)|||/items/af410c06-9878-408f-b451-de312bf73886Montesino, M. (Manuel)|||/items/21d2fa34-149d-43a5-bbd4-b0fe81aceb71Prostatic artery embolization (PAE)Transurethral resection of the prostate (TURP)CostsBenign prostatic hyperplasiaPurpose: To perform a post hoc analysis of patient-incurred costs in a randomized controlled clinical trial comparing prostatic artery embolization (PAE) and transurethral resection of the prostate (TURP). Materials and methods: Patients older than 60 years with indication of TURP were randomized to PAE or TURP procedure. After intervention and hospital discharge, patients were follow-up during 12 months The associated patient costs were categorized according to the study period: pre-intervention, intervention, hospitalization, and follow-up. Several items for both groups were analyzed within each study period. Results: The mean total costs per patient were lower for PAE (€ 3,192.87) than for TURP (€ 3,974.57), with this difference of € 781.70 being significant (p = 0.026). For most evaluated items, the mean costs were significantly higher for TURP. No significant differences were observed in the mean costs of PAE (€ 1,468.00) and TURP (€ 1,684.25) procedures (p = 0.061). However, the histopathology analysis, recovery room stay, and intraoperative laboratory analysis increased the interventional costs for TURP (€ 1,999.70) compared with PAE (€ 1,468.00) (p < 0.001). No cost differences were observed between PAE (€ 725.26) and TURP (€ 556.22) during the 12 months of follow-up (p = 0.605). None of patients required a repeat intervention during the study period. Conclusions: Considering the short-term follow-up, PAE was associated with significantly lower costs compared with TURP. Future investigations in the context of routine clinical practice should be aimed at comparing the long-term effectiveness of both procedures and determining their cost-effectiveness. Level of evidence: Level 1 (a-c).Springer NatureDadun. Depósito Académico Digital Universidad de Navarra20212021-01-0120212021-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/111024reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/1110242026-06-21T12:47:57Z
dc.title.none.fl_str_mv Prostatic artery embolization versus transurethral resection of the prostate: a post hoc cost analysis of a randomized controlled clinical trial
title Prostatic artery embolization versus transurethral resection of the prostate: a post hoc cost analysis of a randomized controlled clinical trial
spellingShingle Prostatic artery embolization versus transurethral resection of the prostate: a post hoc cost analysis of a randomized controlled clinical trial
Capdevila, F. (Ferrán)|||/items/93ed5405-dd06-40e7-a6f4-9a236c191a92
Prostatic artery embolization (PAE)
Transurethral resection of the prostate (TURP)
Costs
Benign prostatic hyperplasia
title_short Prostatic artery embolization versus transurethral resection of the prostate: a post hoc cost analysis of a randomized controlled clinical trial
title_full Prostatic artery embolization versus transurethral resection of the prostate: a post hoc cost analysis of a randomized controlled clinical trial
title_fullStr Prostatic artery embolization versus transurethral resection of the prostate: a post hoc cost analysis of a randomized controlled clinical trial
title_full_unstemmed Prostatic artery embolization versus transurethral resection of the prostate: a post hoc cost analysis of a randomized controlled clinical trial
title_sort Prostatic artery embolization versus transurethral resection of the prostate: a post hoc cost analysis of a randomized controlled clinical trial
dc.creator.none.fl_str_mv Capdevila, F. (Ferrán)|||/items/93ed5405-dd06-40e7-a6f4-9a236c191a92
Insausti-Gorbea, I. (Iñigo)|||/items/8b0a63e0-ccf3-484c-a43f-7bb5847e4ac1
Galbete, A. (Arkaitz)|||/items/ec7b27ee-75e0-40a0-a8ac-993c7832c433
Sanchez-Iriso, E. (Eduardo)|||/items/af410c06-9878-408f-b451-de312bf73886
Montesino, M. (Manuel)|||/items/21d2fa34-149d-43a5-bbd4-b0fe81aceb71
author Capdevila, F. (Ferrán)|||/items/93ed5405-dd06-40e7-a6f4-9a236c191a92
author_facet Capdevila, F. (Ferrán)|||/items/93ed5405-dd06-40e7-a6f4-9a236c191a92
Insausti-Gorbea, I. (Iñigo)|||/items/8b0a63e0-ccf3-484c-a43f-7bb5847e4ac1
Galbete, A. (Arkaitz)|||/items/ec7b27ee-75e0-40a0-a8ac-993c7832c433
Sanchez-Iriso, E. (Eduardo)|||/items/af410c06-9878-408f-b451-de312bf73886
Montesino, M. (Manuel)|||/items/21d2fa34-149d-43a5-bbd4-b0fe81aceb71
author_role author
author2 Insausti-Gorbea, I. (Iñigo)|||/items/8b0a63e0-ccf3-484c-a43f-7bb5847e4ac1
Galbete, A. (Arkaitz)|||/items/ec7b27ee-75e0-40a0-a8ac-993c7832c433
Sanchez-Iriso, E. (Eduardo)|||/items/af410c06-9878-408f-b451-de312bf73886
Montesino, M. (Manuel)|||/items/21d2fa34-149d-43a5-bbd4-b0fe81aceb71
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Dadun. Depósito Académico Digital Universidad de Navarra
dc.subject.none.fl_str_mv Prostatic artery embolization (PAE)
Transurethral resection of the prostate (TURP)
Costs
Benign prostatic hyperplasia
topic Prostatic artery embolization (PAE)
Transurethral resection of the prostate (TURP)
Costs
Benign prostatic hyperplasia
description Purpose: To perform a post hoc analysis of patient-incurred costs in a randomized controlled clinical trial comparing prostatic artery embolization (PAE) and transurethral resection of the prostate (TURP). Materials and methods: Patients older than 60 years with indication of TURP were randomized to PAE or TURP procedure. After intervention and hospital discharge, patients were follow-up during 12 months The associated patient costs were categorized according to the study period: pre-intervention, intervention, hospitalization, and follow-up. Several items for both groups were analyzed within each study period. Results: The mean total costs per patient were lower for PAE (€ 3,192.87) than for TURP (€ 3,974.57), with this difference of € 781.70 being significant (p = 0.026). For most evaluated items, the mean costs were significantly higher for TURP. No significant differences were observed in the mean costs of PAE (€ 1,468.00) and TURP (€ 1,684.25) procedures (p = 0.061). However, the histopathology analysis, recovery room stay, and intraoperative laboratory analysis increased the interventional costs for TURP (€ 1,999.70) compared with PAE (€ 1,468.00) (p < 0.001). No cost differences were observed between PAE (€ 725.26) and TURP (€ 556.22) during the 12 months of follow-up (p = 0.605). None of patients required a repeat intervention during the study period. Conclusions: Considering the short-term follow-up, PAE was associated with significantly lower costs compared with TURP. Future investigations in the context of routine clinical practice should be aimed at comparing the long-term effectiveness of both procedures and determining their cost-effectiveness. Level of evidence: Level 1 (a-c).
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01
2021
2021-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10171/111024
url https://hdl.handle.net/10171/111024
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra
instname:Universidad de Navarra
instname_str Universidad de Navarra
reponame_str Dadun. Depósito Académico Digital de la Universidad de Navarra
collection Dadun. Depósito Académico Digital de la Universidad de Navarra
repository.name.fl_str_mv
repository.mail.fl_str_mv
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