A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines

We report the sustainable and efficient synthesis of a new type of quinoline derivatives bearing one or two SOCF groups. The protocol is metal-, catalyst- and irradiation-free, involves the use of readily available and stable precursors, and avoids the formation of side products. Also, the mild cond...

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Detalles Bibliográficos
Autores: Lázaro-Milla, Carlos, Almendros, Pedro
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/253661
Acceso en línea:http://hdl.handle.net/10261/253661
Access Level:acceso abierto
Palabra clave:Alkenes
Allenes
Fluorine
Metal-free reactions
Synthetic methods
Descripción
Sumario:We report the sustainable and efficient synthesis of a new type of quinoline derivatives bearing one or two SOCF groups. The protocol is metal-, catalyst- and irradiation-free, involves the use of readily available and stable precursors, and avoids the formation of side products. Also, the mild conditions of the process allow the tolerance of a wide range of functional groups.