Pneumococcal biofilms

9 páginas, 3 figuras -- PAGS nros. 77-85

Detalles Bibliográficos
Autores: Moscoso, Miriam, García, Ernesto, López, Rubens
Tipo de recurso: artículo
Fecha de publicación:2009
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/56100
Acceso en línea:http://hdl.handle.net/10261/56100
Access Level:acceso abierto
Palabra clave:Streptococcus pneumoniae
Biofilms
Quorum sensing
Otitis media
Extracellular matrix
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spelling Pneumococcal biofilmsMoscoso, MiriamGarcía, ErnestoLópez, RubensStreptococcus pneumoniaeBiofilmsQuorum sensingOtitis mediaExtracellular matrix9 páginas, 3 figuras -- PAGS nros. 77-85Over 60% of bacterial infections (and up to 80% of chronic infections) are currently considered to involve microbial growth in biofilms. This peculiar form of life poses an array of problems in human clinical practice, from infections associated with the implant of prosthetic devices and dental plaque formation to diseases such as cystic fibrosis, otitis media, and endocarditis. Biofilms are also at the basis of a variety of problems in industry. This report describes the biofilms produced by Streptococcus pneumoniae. This bacterium often colonizes the upper airways in humans as a normal commensal, yet it may spread to other areas of the body, causing otitis media, pneumonia, or invasive diseases such as bacteremia and meningitis. The capacity of S. pneumoniae to form biofilms had not been explored until recently. Several newly developed in vitro systems have allowed to test the capacity of S. pneumoniae to form biofilms, and to analyze the influence of several factors, including DNA and proteins—which play a role in the virulence of this “supergerm” in the formation and development of biofilms. In this brief review, we update the knowledge available on pneumococcal biofilm formation and the unusual features of this structureWork in the authors’ laboratory was supported by a grant from the Spanish Directorate-General for Scientific and Technical Research (SAF2006-00390). CIBER de Enfermedades Respiratorias (CIBERES) is an initiative of ISCIIIPeer reviewedSpringer Nature201220122009info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://hdl.handle.net/10261/56100reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://dx.doi.org/10.2436/20.1501.01.84info:eu-repo/semantics/openAccessoai:digital.csic.es:10261/561002026-05-22T06:33:51Z
dc.title.none.fl_str_mv Pneumococcal biofilms
title Pneumococcal biofilms
spellingShingle Pneumococcal biofilms
Moscoso, Miriam
Streptococcus pneumoniae
Biofilms
Quorum sensing
Otitis media
Extracellular matrix
title_short Pneumococcal biofilms
title_full Pneumococcal biofilms
title_fullStr Pneumococcal biofilms
title_full_unstemmed Pneumococcal biofilms
title_sort Pneumococcal biofilms
dc.creator.none.fl_str_mv Moscoso, Miriam
García, Ernesto
López, Rubens
author Moscoso, Miriam
author_facet Moscoso, Miriam
García, Ernesto
López, Rubens
author_role author
author2 García, Ernesto
López, Rubens
author2_role author
author
dc.subject.none.fl_str_mv Streptococcus pneumoniae
Biofilms
Quorum sensing
Otitis media
Extracellular matrix
topic Streptococcus pneumoniae
Biofilms
Quorum sensing
Otitis media
Extracellular matrix
description 9 páginas, 3 figuras -- PAGS nros. 77-85
publishDate 2009
dc.date.none.fl_str_mv 2009
2012
2012
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/56100
url http://hdl.handle.net/10261/56100
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://dx.doi.org/10.2436/20.1501.01.84
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.811543

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