Integrated micro- and nano-optical biosensor silicon devices CMOS compatible
15 páginas, 18 figuras.-- Trabajo presentado en la conferencia "Optoelectronic Integration on Silicon"; San Jose, CA (USA); 15-Julio-2004; Editores: David J. Robbins, Ghassan E. Jabbour .
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2004 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/27901 |
| Acceso en línea: | http://hdl.handle.net/10261/27901 |
| Access Level: | acceso abierto |
| Palabra clave: | Optical biosensor Mach-Zehnder interferometer Integrated optics BioMEMS Optical waveguides Immobilization at nanometer scale |
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Integrated micro- and nano-optical biosensor silicon devices CMOS compatibleLechuga, Laura M.Sepúlveda, BorjaSánchez del Río, JoséBlanco, Francisco J.Calle Martín, AnaDomínguez Horna, CarlosOptical biosensorMach-Zehnder interferometerIntegrated opticsBioMEMSOptical waveguidesImmobilization at nanometer scale15 páginas, 18 figuras.-- Trabajo presentado en la conferencia "Optoelectronic Integration on Silicon"; San Jose, CA (USA); 15-Julio-2004; Editores: David J. Robbins, Ghassan E. Jabbour .We show the design, fabrication and testing of micro/nanobiosensor devices based on optical waveguides in a highly sensitive interferometric configuration and by using evanescent wave detection. The devices are fabricated by standard Silicon CMOS microelectronics technology after a precise design for achieving a high sensitivity for biosensing applications. Two integrated Mach-Zehnder interferometric (MZI) devices, using two technologies, have been developed: (a) a MZI Microdevice based on ARROW waveguide (b) a MZI Nanodevice based on TIR waveguide. Direct biosensing with both sensors has been tested, after a specific receptor coupling to the surface device using nanometer scale immobilization techniques. Further integration of the microoptical sensors, the microfluidics, the photodetectors and the CMOS electronics will render in a lab-on-a-chip microsystem.This work has been supported by the national project BIO2000-0351-P4. B Sepúlveda acknowledges CSIC-I3P program the financial support for Ph. D. studies.Peer reviewedThe International Society for Optics and PhotonicsConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]201020102004info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501459230 bytesapplication/pdfhttp://hdl.handle.net/10261/27901reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://dx.doi.org/10.1117/12.521104Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/279012026-05-22T06:33:51Z |
| dc.title.none.fl_str_mv |
Integrated micro- and nano-optical biosensor silicon devices CMOS compatible |
| title |
Integrated micro- and nano-optical biosensor silicon devices CMOS compatible |
| spellingShingle |
Integrated micro- and nano-optical biosensor silicon devices CMOS compatible Lechuga, Laura M. Optical biosensor Mach-Zehnder interferometer Integrated optics BioMEMS Optical waveguides Immobilization at nanometer scale |
| title_short |
Integrated micro- and nano-optical biosensor silicon devices CMOS compatible |
| title_full |
Integrated micro- and nano-optical biosensor silicon devices CMOS compatible |
| title_fullStr |
Integrated micro- and nano-optical biosensor silicon devices CMOS compatible |
| title_full_unstemmed |
Integrated micro- and nano-optical biosensor silicon devices CMOS compatible |
| title_sort |
Integrated micro- and nano-optical biosensor silicon devices CMOS compatible |
| dc.creator.none.fl_str_mv |
Lechuga, Laura M. Sepúlveda, Borja Sánchez del Río, José Blanco, Francisco J. Calle Martín, Ana Domínguez Horna, Carlos |
| author |
Lechuga, Laura M. |
| author_facet |
Lechuga, Laura M. Sepúlveda, Borja Sánchez del Río, José Blanco, Francisco J. Calle Martín, Ana Domínguez Horna, Carlos |
| author_role |
author |
| author2 |
Sepúlveda, Borja Sánchez del Río, José Blanco, Francisco J. Calle Martín, Ana Domínguez Horna, Carlos |
| author2_role |
author author author author author |
| dc.contributor.none.fl_str_mv |
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] |
| dc.subject.none.fl_str_mv |
Optical biosensor Mach-Zehnder interferometer Integrated optics BioMEMS Optical waveguides Immobilization at nanometer scale |
| topic |
Optical biosensor Mach-Zehnder interferometer Integrated optics BioMEMS Optical waveguides Immobilization at nanometer scale |
| description |
15 páginas, 18 figuras.-- Trabajo presentado en la conferencia "Optoelectronic Integration on Silicon"; San Jose, CA (USA); 15-Julio-2004; Editores: David J. Robbins, Ghassan E. Jabbour . |
| publishDate |
2004 |
| dc.date.none.fl_str_mv |
2004 2010 2010 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 |
| format |
article |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10261/27901 |
| url |
http://hdl.handle.net/10261/27901 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
http://dx.doi.org/10.1117/12.521104 Sí |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
459230 bytes application/pdf |
| dc.publisher.none.fl_str_mv |
The International Society for Optics and Photonics |
| publisher.none.fl_str_mv |
The International Society for Optics and Photonics |
| dc.source.none.fl_str_mv |
reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC instname:Consejo Superior de Investigaciones Científicas (CSIC) |
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Consejo Superior de Investigaciones Científicas (CSIC) |
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DIGITAL.CSIC. Repositorio Institucional del CSIC |
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DIGITAL.CSIC. Repositorio Institucional del CSIC |
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| _version_ |
1869405128388247552 |
| score |
15,811543 |