Simultaneous Bilateral Video-Endoscopic Inguinal Lymphadenectomy for Penile Carcinoma

Inguinal lymph node dissection (ILND) plays an important role for both staging and treatment purposes in patients diagnosed with penile carcinoma (PeCa). Video-endoscopic inguinal lymphadenectomy (VEIL) has been introduced to reduce complications, and in those patients elected for bilateral ILND, a...

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Detalles Bibliográficos
Autores: Gaya, Josep Maria|||0000-0002-4202-222X, Basile, Giuseppe|||0000-0002-7227-7821, Gavrilov, Pavel, Gallioli, Andrea|||0000-0002-3316-5691, Territo, Angelo|||0000-0002-5162-5356, Robalino, Jorge, Hernandez, Pedro, Sánchez Molina, Raúl|||0000-0002-1288-7716, Bravo-Balado, Alejandra|||0000-0002-9555-393X, Algaba, Ferran|||0000-0002-0071-4164, Huguet Perez, Jordi, Sanguedolce, Francesco|||0000-0002-5242-7060, Palou, Juan|||0000-0003-1264-5327, Rosales, Antonio, Breda, Alberto|||0000-0002-7842-9048
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:296601
Acceso en línea:https://ddd.uab.cat/record/296601
https://dx.doi.org/urn:doi:10.3390/jcm12237272
Access Level:acceso abierto
Palabra clave:Inguinal lymph node dissection
Invasive inguinal staging
Minimally invasive surgery
Penile carcinoma
Video-endoscopic inguinal lymphadenectomy
Descripción
Sumario:Inguinal lymph node dissection (ILND) plays an important role for both staging and treatment purposes in patients diagnosed with penile carcinoma (PeCa). Video-endoscopic inguinal lymphadenectomy (VEIL) has been introduced to reduce complications, and in those patients elected for bilateral ILND, a simultaneous bilateral VEIL (sB-VEIL) has also been proposed. This study aimed to investigate the feasibility, safety, and preliminary oncological outcomes of sB-VEIL compared to consecutive bilateral VEIL (cB-VEIL). Clinical N0-2 patients diagnosed with PeCa and treated with cB-VEIL and sB-VEIL between 2015 and 2023 at our institution were included. Modified ILND was performed in cN0 patients, while cN+ patients underwent a radical approach. Intra- and postoperative complications, operative time, time of drainage maintenance, length of hospital stay and readmission within 90 days, as well as lymph node yield, were compared between the two groups. Overall, 30 patients were submitted to B-VEIL. Of these, 20 and 10 patients underwent cB-VEIL and sB-VEIL, respectively. Overall, 16 (80%) and 7 (70%) patients were submitted to radical ILND due to cN1-2 disease in the cB-VEIL and sB-VEIL groups, respectively. No statistically significant difference emerged in terms of median nodal yield (13.5 vs. 14, p = 0.7) and median positive LNs (p = 0.9). sD-VEIL was associated with a shorter operative time (170 vs. 240 min, p < 0.01). No statistically significant difference emerged in terms of intraoperative estimated blood loss, length of hospital stay, time to drainage tube removal, major complications, and hospital readmission in the cB-VEIL and sB-VEIL groups, respectively (all p.