Assessment of human dietary exposure to arsenic through rice

Rice accumulates 10-fold higher inorganic arsenic (i-As), an established human carcinogen, than other grains. This review summarizes epidemiologic studies that examined the association between rice consumption and biomarkers of arsenic exposure. After reviewing the literature we identified 20 studie...

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Detalles Bibliográficos
Autores: Davis, Matthew A., Signes-Pastor, Antonio Jose, Argos, Maria, Slaughter, Francis, Pendergrast, Claire, Punshon, Tracy, Gossai, Anala, Ahsan, Habibul, Karagas, Margaret R
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universidad Miguel Hernández de Elche
Repositorio:REDIUMH. Depósito Digital de la UMH
OAI Identifier:oai:dnet:rediumh_____::136833faa174feb49324c9e92847f007
Acceso en línea:https://hdl.handle.net/11000/39813
Access Level:acceso abierto
Palabra clave:Arsenic metabolites
Bio monitoring
Dietary
Exposure
Rice
Urine
Toenails
Descripción
Sumario:Rice accumulates 10-fold higher inorganic arsenic (i-As), an established human carcinogen, than other grains. This review summarizes epidemiologic studies that examined the association between rice consumption and biomarkers of arsenic exposure. After reviewing the literature we identified 20 studies, among them included 18 observational and 2 human experimental studies that reported on associations between rice consumption and an arsenic biomarker. Among individuals not exposed to contaminated water, rice is a source of i-As exposure – rice consumption has been consistently related to arsenic biomarkers, and the relationship has been clearly demonstrated in experimental studies. Early-life i-As exposure is of particular concern due to its associationwith lifelong adverse health outcomes. Maternal rice consumption during pregnancy also has been associatedwith infant toenail total arsenic concentrations indicating that dietary exposure during pregnancy results in fetal exposure. Thus, the collective evidence indicates that rice is an independent source of arsenic exposure in populations around the world and highlights the importance of investigating its affect on health.