Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia

Background: Non-invasive molecular biomarkers for classifying azoospermia by origin into either obstructive or non-obstructive/secretory azoospermia, as well as for inferring the spermatogenic reserve of the testis of non-obstructive/secretory azoospermia patients, are of great interest for testicul...

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Detalles Bibliográficos
Autores: Larriba, Sara, Sánchez Herrero, José Francisco, Pluvinet Ortega, Raquel, López Rodrigo, Olga, Bassas, Lluís, Sumoy, Lauro
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2023
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/200868
Acceso en línea:https://hdl.handle.net/2445/200868
Access Level:acceso abierto
Palabra clave:Esterilitat masculina
Investigació mèdica
Male sterility
Medicine research
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spelling Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermiaLarriba, SaraSánchez Herrero, José FranciscoPluvinet Ortega, RaquelLópez Rodrigo, OlgaBassas, LluísSumoy, LauroEsterilitat masculinaInvestigació mèdicaMale sterilityMedicine researchBackground: Non-invasive molecular biomarkers for classifying azoospermia by origin into either obstructive or non-obstructive/secretory azoospermia, as well as for inferring the spermatogenic reserve of the testis of non-obstructive/secretory azoospermia patients, are of great interest for testicular sperm retrieval outcome prediction for assisted reproduction. Prior analyses of semen small non-coding RNA expression in azoospermia have focused on microRNAs, but there has been a lack of attention on other regulatory small RNA species. In this regard, studying more in-depth expression changes of small non-coding RNA subtypes in small extracellular vesicles from semen of azoospermic individuals could be useful to select additional non-invasive biomarkers with diagnostic/prognostic purposes.Wiley2023202420232023info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion58 p.application/pdfhttps://hdl.handle.net/2445/200868Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1111/andr.13461Andrology, 2023https://doi.org/10.1111/andr.13461(c) Wiley, 2023info:eu-repo/semantics/openAccessoai:recercat.cat:2445/2008682026-05-29T05:05:01Z
dc.title.none.fl_str_mv Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia
title Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia
spellingShingle Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia
Larriba, Sara
Esterilitat masculina
Investigació mèdica
Male sterility
Medicine research
title_short Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia
title_full Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia
title_fullStr Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia
title_full_unstemmed Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia
title_sort Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia
dc.creator.none.fl_str_mv Larriba, Sara
Sánchez Herrero, José Francisco
Pluvinet Ortega, Raquel
López Rodrigo, Olga
Bassas, Lluís
Sumoy, Lauro
author Larriba, Sara
author_facet Larriba, Sara
Sánchez Herrero, José Francisco
Pluvinet Ortega, Raquel
López Rodrigo, Olga
Bassas, Lluís
Sumoy, Lauro
author_role author
author2 Sánchez Herrero, José Francisco
Pluvinet Ortega, Raquel
López Rodrigo, Olga
Bassas, Lluís
Sumoy, Lauro
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Esterilitat masculina
Investigació mèdica
Male sterility
Medicine research
topic Esterilitat masculina
Investigació mèdica
Male sterility
Medicine research
description Background: Non-invasive molecular biomarkers for classifying azoospermia by origin into either obstructive or non-obstructive/secretory azoospermia, as well as for inferring the spermatogenic reserve of the testis of non-obstructive/secretory azoospermia patients, are of great interest for testicular sperm retrieval outcome prediction for assisted reproduction. Prior analyses of semen small non-coding RNA expression in azoospermia have focused on microRNAs, but there has been a lack of attention on other regulatory small RNA species. In this regard, studying more in-depth expression changes of small non-coding RNA subtypes in small extracellular vesicles from semen of azoospermic individuals could be useful to select additional non-invasive biomarkers with diagnostic/prognostic purposes.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023
2023
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/200868
url https://hdl.handle.net/2445/200868
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1111/andr.13461
Andrology, 2023
https://doi.org/10.1111/andr.13461
dc.rights.none.fl_str_mv (c) Wiley, 2023
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Wiley, 2023
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 58 p.
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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