Identification of weakly haemolytic Brachyspira isolates recovered from pigs with diarrhoea in Spain and Portugal and comparison with results from other countries

[EN] Weakly haemolytic anaerobic intestinal spirochaetes of the genus Brachyspira are commonly identified based on species-specific gene sequences. Apart from the pathogenic Brachyspira pilosicoli, the distribution and disease associations of the other weakly haemolytic Brachyspira species in pigs h...

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Detalles Bibliográficos
Autores: Osorio, Jesús, Carvajal Urueña, Ana María, Naharro Carrasco, Germán, Plans Rubió, Pedro, La, Tom, Phillips, Nyree Dale, Hampson, David J.
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2013
País:España
Institución:Universidad de León
Repositorio:BULERIA. Repositorio Institucional de la Universidad de León
OAI Identifier:oai:buleria.unileon.es:10612/24996
Acceso en línea:https://www.sciencedirect.com/science/article/pii/S0034528813002397
https://hdl.handle.net/10612/24996
https://doi.org/10.1016/j.rvsc.2013.07.014
Access Level:acceso abierto
Palabra clave:Veterinaria
Pig
Brachyspira
Nox
MLST
Spain
Portugal
3109 Ciencias Veterinarias
Descripción
Sumario:[EN] Weakly haemolytic anaerobic intestinal spirochaetes of the genus Brachyspira are commonly identified based on species-specific gene sequences. Apart from the pathogenic Brachyspira pilosicoli, the distribution and disease associations of the other weakly haemolytic Brachyspira species in pigs have not been comprehensively investigated. In this study weakly haemolytic Brachyspira isolates (n = 67) from Spanish and Portuguese pigs with diarrhoea, negative in a routine diagnostic PCR for B. pilosicoli, were identified by sequencing their NADH oxidase genes (nox). Nearly half the isolates were identified as Brachyspira murdochii (n = 31; 46.3%). The others were Brachyspira innocens (n = 26; 38.8%), Brachyspira intermedia (n = 7; 10.4%), “Brachyspira pulli” (n = 1; 1.5%) and a potentially novel Brachyspira species (n = 2; 3%). Multilocus sequence typing (MLST) on a subset of 18 isolates confirmed their species designations, including the potential new species, and identified similarities to strains from other countries.