Large-scale production of superparamagnetic iron oxide nanoparticles by flame spray pyrolysis: in vitro biological evaluation for biomedical applications

Despite the large number of synthesis methodologies described for superparamagnetic iron oxide nanoparticles (SPIONs), the search for their large-scale production for their widespread use in biomedical applications remains a mayor challenge. Flame Spray Pyrolysis (FSP) could be the solution to solve...

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Detalles Bibliográficos
Autores: Gutiérrez Estévez, Manuel, Cicuéndez Maroto, Mónica, Crespo, Julián, Serrano-López, Juana, Colilla Nieto, Montserrat, Fernández-Acevedo, Claudio, Oroz-Mateo, Tamara, Rada-Leza, Amaia, González Ortiz, Blanca, Izquierdo Barba, Isabel, Vallet Regí, María Dulce Nombre
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/87969
Acceso en línea:https://hdl.handle.net/20.500.14352/87969
Access Level:acceso abierto
Palabra clave:615.46
546
Superparamagnetic iron oxide nanoparticles
Flame spray pyrolysis
Large-scale production
Biocompatibility
Hemocompatibility
Human mesenchymal stem cells
Biomedical applications
Química inorgánica (Farmacia)
Materiales
2303 Química Inorgánica
Descripción
Sumario:Despite the large number of synthesis methodologies described for superparamagnetic iron oxide nanoparticles (SPIONs), the search for their large-scale production for their widespread use in biomedical applications remains a mayor challenge. Flame Spray Pyrolysis (FSP) could be the solution to solve this limitation, since it allows the fabrication of metal oxide nanoparticles with high production yield and low manufacture costs. However, to our knowledge, to date such fabrication method has not been upgraded for biomedical purposes. Herein, SPIONs

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