Alcohol intake, wine consumption and the development of depression: the PREDIMED study

Background: Alcoholic beverages are widely consumed. Depression, the most prevalent mental disorder worldwide, has been related to alcohol intake. We aimed to prospectively assess the association between alcohol intake and incident depression using repeated measurements of alcohol intake. Methods: W...

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Autores: Gea, Alfredo, Beunza, Juan J., Estruch Riba, Ramon, Sánchez-Villegas, Almudena, Salas Salvadó, Jordi, Buil Cosiales, Pilar, Gómez Gracia, Enrique, Covas Planells, María Isabel, Corella Piquer, Dolores, Fiol Sala, Miguel, Arós, Fernando, Lapetra, José, Lamuela Raventós, Rosa Ma., Wärnberg, Julia, Pintó Sala, Xavier, Serra Majem, Lluís, Martínez-González, Miguel Ángel, 1957-
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/100753
Acceso en línea:https://hdl.handle.net/2445/100753
Access Level:acceso abierto
Palabra clave:Consum d'alcohol
Vi
Depressió psíquica
Drinking of alcoholic beverages
Wine
Mental depression
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spelling Alcohol intake, wine consumption and the development of depression: the PREDIMED studyGea, AlfredoBeunza, Juan J.Estruch Riba, RamonSánchez-Villegas, AlmudenaSalas Salvadó, JordiBuil Cosiales, PilarGómez Gracia, EnriqueCovas Planells, María IsabelCorella Piquer, DoloresFiol Sala, MiguelArós, FernandoLapetra, JoséLamuela Raventós, Rosa Ma.Wärnberg, JuliaPintó Sala, XavierSerra Majem, LluísMartínez-González, Miguel Ángel, 1957-Consum d'alcoholViDepressió psíquicaDrinking of alcoholic beveragesWineMental depressionBackground: Alcoholic beverages are widely consumed. Depression, the most prevalent mental disorder worldwide, has been related to alcohol intake. We aimed to prospectively assess the association between alcohol intake and incident depression using repeated measurements of alcohol intake. Methods: We followed-up 5,505 high-risk men and women (55 to 80 y) of the PREDIMED Trial for up to seven years. Participants were initially free of depression or a history of depression, and did not have any history of alcohol-related problems. A 137-item validated food frequency questionnaire administered by a dietician was repeated annually to assess alcohol intake. Participants were classified as incident cases of depression when they reported a new clinical diagnosis of depression, and/or initiated the use of antidepressant drugs. Cox regression analyses were fitted over 23,655 person-years. Results: Moderate alcohol intake within the range of 5 to 15 g/day was significantly associated with lower risk of incident depression (hazard ratio (HR) and 95% confidence interval (95% CI) = 0.72 (0.53 to 0.98) versus abstainers). Specifically, wine consumption in the range of two to seven drinks/week was significantly associated with lower rates of depression (HR (95% CI) = 0.68 (0.47 to 0.98)). Conclusions: Moderate consumption of wine may reduce the incidence of depression, while heavy drinkers seem to be at higher risk.BioMed Central2016201620132016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/100753Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: http://dx.doi.org/10.1186/1741-7015-11-192BMC Medicine, 2013, vol. 11, num. 192http://dx.doi.org/10.1186/1741-7015-11-192cc-by (c) BioMed Central, 2013http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:recercat.cat:2445/1007532026-05-29T05:05:01Z
dc.title.none.fl_str_mv Alcohol intake, wine consumption and the development of depression: the PREDIMED study
title Alcohol intake, wine consumption and the development of depression: the PREDIMED study
spellingShingle Alcohol intake, wine consumption and the development of depression: the PREDIMED study
Gea, Alfredo
Consum d'alcohol
Vi
Depressió psíquica
Drinking of alcoholic beverages
Wine
Mental depression
title_short Alcohol intake, wine consumption and the development of depression: the PREDIMED study
title_full Alcohol intake, wine consumption and the development of depression: the PREDIMED study
title_fullStr Alcohol intake, wine consumption and the development of depression: the PREDIMED study
title_full_unstemmed Alcohol intake, wine consumption and the development of depression: the PREDIMED study
title_sort Alcohol intake, wine consumption and the development of depression: the PREDIMED study
dc.creator.none.fl_str_mv Gea, Alfredo
Beunza, Juan J.
Estruch Riba, Ramon
Sánchez-Villegas, Almudena
Salas Salvadó, Jordi
Buil Cosiales, Pilar
Gómez Gracia, Enrique
Covas Planells, María Isabel
Corella Piquer, Dolores
Fiol Sala, Miguel
Arós, Fernando
Lapetra, José
Lamuela Raventós, Rosa Ma.
Wärnberg, Julia
Pintó Sala, Xavier
Serra Majem, Lluís
Martínez-González, Miguel Ángel, 1957-
author Gea, Alfredo
author_facet Gea, Alfredo
Beunza, Juan J.
Estruch Riba, Ramon
Sánchez-Villegas, Almudena
Salas Salvadó, Jordi
Buil Cosiales, Pilar
Gómez Gracia, Enrique
Covas Planells, María Isabel
Corella Piquer, Dolores
Fiol Sala, Miguel
Arós, Fernando
Lapetra, José
Lamuela Raventós, Rosa Ma.
Wärnberg, Julia
Pintó Sala, Xavier
Serra Majem, Lluís
Martínez-González, Miguel Ángel, 1957-
author_role author
author2 Beunza, Juan J.
Estruch Riba, Ramon
Sánchez-Villegas, Almudena
Salas Salvadó, Jordi
Buil Cosiales, Pilar
Gómez Gracia, Enrique
Covas Planells, María Isabel
Corella Piquer, Dolores
Fiol Sala, Miguel
Arós, Fernando
Lapetra, José
Lamuela Raventós, Rosa Ma.
Wärnberg, Julia
Pintó Sala, Xavier
Serra Majem, Lluís
Martínez-González, Miguel Ángel, 1957-
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Consum d'alcohol
Vi
Depressió psíquica
Drinking of alcoholic beverages
Wine
Mental depression
topic Consum d'alcohol
Vi
Depressió psíquica
Drinking of alcoholic beverages
Wine
Mental depression
description Background: Alcoholic beverages are widely consumed. Depression, the most prevalent mental disorder worldwide, has been related to alcohol intake. We aimed to prospectively assess the association between alcohol intake and incident depression using repeated measurements of alcohol intake. Methods: We followed-up 5,505 high-risk men and women (55 to 80 y) of the PREDIMED Trial for up to seven years. Participants were initially free of depression or a history of depression, and did not have any history of alcohol-related problems. A 137-item validated food frequency questionnaire administered by a dietician was repeated annually to assess alcohol intake. Participants were classified as incident cases of depression when they reported a new clinical diagnosis of depression, and/or initiated the use of antidepressant drugs. Cox regression analyses were fitted over 23,655 person-years. Results: Moderate alcohol intake within the range of 5 to 15 g/day was significantly associated with lower risk of incident depression (hazard ratio (HR) and 95% confidence interval (95% CI) = 0.72 (0.53 to 0.98) versus abstainers). Specifically, wine consumption in the range of two to seven drinks/week was significantly associated with lower rates of depression (HR (95% CI) = 0.68 (0.47 to 0.98)). Conclusions: Moderate consumption of wine may reduce the incidence of depression, while heavy drinkers seem to be at higher risk.
publishDate 2013
dc.date.none.fl_str_mv 2013
2016
2016
2016
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/100753
url https://hdl.handle.net/2445/100753
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://dx.doi.org/10.1186/1741-7015-11-192
BMC Medicine, 2013, vol. 11, num. 192
http://dx.doi.org/10.1186/1741-7015-11-192
dc.rights.none.fl_str_mv cc-by (c) BioMed Central, 2013
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) BioMed Central, 2013
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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