Systematic Characterization of High-Power Short-Duration Ablation

Background: High-power short-duration (HPSD) recently emerged as a new approach to radiofrequency (RF) catheter ablation. However, basic and clinical data supporting its effectiveness and safety is still scarce. Objective: We aim to characterize HPSD with an advanced virtual model, able to assess le...

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Detalles Bibliográficos
Autores: Petras, Argyrios, Moreno Weidmann, Zoraida|||0000-0003-1071-4077, Leoni, Massimiliano, Gerardo-Giorda, Luca, Guerra Ramos, José María|||0000-0001-5397-9177
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:252201
Acceso en línea:https://ddd.uab.cat/record/252201
https://dx.doi.org/urn:doi:10.3389/fmedt.2021.747609
Access Level:acceso abierto
Palabra clave:Radiofrequency ablation
High-power short-duration
Computational modeling
Lesion science
Ablation catheter
Descripción
Sumario:Background: High-power short-duration (HPSD) recently emerged as a new approach to radiofrequency (RF) catheter ablation. However, basic and clinical data supporting its effectiveness and safety is still scarce. Objective: We aim to characterize HPSD with an advanced virtual model, able to assess lesion dimensions and complications in multiple conditions and compare it to standard protocols. Methods: We evaluate, on both atrium and ventricle, three HPSD protocols (70 W/8 s, 80 W/6 s, and 90 W/4 s) through a realistic 3D computational model of power-controlled RF ablation, varying catheter tip design (spherical/cylindrical), contact force (CF), blood flow, and saline irrigation. Lesions are defined by the 50°C isotherm contour. Ablations are deemed safe or complicated by pop (tissue temperature.