Pressurized liquid extraction of oak leaf polyphenols: Solvent selection via Hansen parameters, antioxidant evaluation and monoamine-oxidase-a inhibition analysis
This study focuses on the extraction of bioactive compounds from Quercus sideroxyla Bonpl., leaves which have been shown to possess health benefits. The extraction process was done using pressurized liquid extraction (PLE), which is efficient and preserves heat-sensitive compounds. Key factors in th...
| Autores: | , , , , , , , , |
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| Formato: | artículo |
| Fecha de publicación: | 2024 |
| País: | España |
| Recursos: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/372940 |
| Acesso em linha: | http://hdl.handle.net/10261/372940 |
| Access Level: | acceso abierto |
| Palavra-chave: | http://metadata.un.org/sdg/9 http://metadata.un.org/sdg/12 http://metadata.un.org/sdg/1 http://metadata.un.org/sdg/2 http://metadata.un.org/sdg/4 End poverty in all its forms everywhere End hunger, achieve food security and improved nutrition and promote sustainable agriculture Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation Ensure sustainable consumption and production patterns |
| Resumo: | This study focuses on the extraction of bioactive compounds from Quercus sideroxyla Bonpl., leaves which have been shown to possess health benefits. The extraction process was done using pressurized liquid extraction (PLE), which is efficient and preserves heat-sensitive compounds. Key factors in the process included the choice of solvents, pressure, temperature, and extraction duration. The Hansen solubility parameters analysis aided in selecting effective solvents, such as ethanol and benzyl alcohol. The extracts were found to contain phenolic compounds, flavonoids, and polyphenols with antioxidant properties. The UPLC-PDA-ESI-QqQ was employed for the precise identification and quantification of these compounds, demonstrating superior extraction of quinic acid and gallic acid at elevated temperatures. Notably, the extracts obtained through PLE exhibited significant inhibitory activity of the MAO-A enzyme, linked to neuronal and cognitive health, suggesting potential benefits in these areas. |
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