Evaluation of the anticoccidial efficacy of Cycostat (R) in experimentally infected breeding rabbits housed under conventional conditions

The present study was designed in order to evaluate the effi cacy and safety of Cycostat (R) 66G in the prevention and control of coccidiosis in breeding does after experimentally induced infection with common Eimeria spp. at the age of 18 wk. The inoculum was prepared based on faecal samples collec...

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Detalhes bibliográficos
Autores: Maertens, L., Van Gaver, D.
Tipo de documento: artigo
Data de publicação:2010
País:España
Recursos:Universitat Politècnica de València (UPV)
Repositório:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglês
OAI Identifier:oai:riunet.upv.es:10251/8432
Acesso em linha:https://riunet.upv.es/handle/10251/8432
Access Level:Acceso aberto
Palavra-chave:Cycostat (R)
Oocyst excretion
Performance
Cycostat
Rabbit does
Coccidiosis
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spelling Evaluation of the anticoccidial efficacy of Cycostat (R) in experimentally infected breeding rabbits housed under conventional conditionsMaertens, L.Van Gaver, D.Cycostat (R)Oocyst excretionPerformanceCycostatRabbit doesCoccidiosisThe present study was designed in order to evaluate the effi cacy and safety of Cycostat (R) 66G in the prevention and control of coccidiosis in breeding does after experimentally induced infection with common Eimeria spp. at the age of 18 wk. The inoculum was prepared based on faecal samples collected on farms in the Czech Republic. A total of 94 young and pregnant does were divided into 4 groups and enrolled in the study. The zootechnical, clinical and parasitological results of 2 control groups were compared, a non-infected non-treated (NI-NT) and an infected non-treated (I-NT), and 2 infected and dietary supplemented groups, with 50 (I-50) and 66 mg/kg (I-66) robenidine, respectively. Does in the I-NT group showed a significant drop in weight gain and feed intake during the fi rst 14 d after inoculation. No treatment related effects on the weight development of the does were observed, although does in the I-NT group always had approximately ± 200 g lower body weight. Litter size (live born) was not signifi cantly different at either the fi rst or second parturition and amounted to 9.0, 8.2, 10.1 and 9.8 (1st litter) and 11.3, 10.4, 10.1 and 11.0 (2nd litter) in NI-NT, I-NT, I-50 and I-66 does, respectively. At weaning, both in the 1st and 2nd cycle, the highest litter weight was obtained in the I-50 and I-66 groups. Litter weaning weight values for I-66 (litter 2) were higher but not significant (P=0.069) compared to the NI-NT litters. The lowest young mortality was also observed in the I-66 litters, both in the first and second cycles. Between 6 to 11 d after inoculation, the oocyst excretion of both supplemented groups was reduced by more than 90% in comparison to the I-NT. Supplementation with Cycostat (R) 66G diminished the excretion of E. flavescens and E. intestinalis, the most pathogenic species, by 100%. The excretion of E. magna was reduced by >90 and 100% for the I-50 and I-66 groups, respectively. The reduction in oocyst excretion of E. media was less pronounced. It was concluded that Cycostat (R) 66G supplemented in the feed at a concentration of 50 or 66mg/kg was able to prevent coccidiosis in breeding does after experimental inoculation.World Rabbit Science. ICTA. UPVRepositorio Institucional de la Universitat Politècnica de València Riunet20102010-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://riunet.upv.es/handle/10251/8432reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Reserva de todos los derechoshttp://rightsstatements.org/vocab/InC/1.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/84322026-06-13T07:49:27Z
dc.title.none.fl_str_mv Evaluation of the anticoccidial efficacy of Cycostat (R) in experimentally infected breeding rabbits housed under conventional conditions
title Evaluation of the anticoccidial efficacy of Cycostat (R) in experimentally infected breeding rabbits housed under conventional conditions
spellingShingle Evaluation of the anticoccidial efficacy of Cycostat (R) in experimentally infected breeding rabbits housed under conventional conditions
Maertens, L.
Cycostat (R)
Oocyst excretion
Performance
Cycostat
Rabbit does
Coccidiosis
title_short Evaluation of the anticoccidial efficacy of Cycostat (R) in experimentally infected breeding rabbits housed under conventional conditions
title_full Evaluation of the anticoccidial efficacy of Cycostat (R) in experimentally infected breeding rabbits housed under conventional conditions
title_fullStr Evaluation of the anticoccidial efficacy of Cycostat (R) in experimentally infected breeding rabbits housed under conventional conditions
title_full_unstemmed Evaluation of the anticoccidial efficacy of Cycostat (R) in experimentally infected breeding rabbits housed under conventional conditions
title_sort Evaluation of the anticoccidial efficacy of Cycostat (R) in experimentally infected breeding rabbits housed under conventional conditions
dc.creator.none.fl_str_mv Maertens, L.
Van Gaver, D.
author Maertens, L.
author_facet Maertens, L.
Van Gaver, D.
author_role author
author2 Van Gaver, D.
author2_role author
dc.contributor.none.fl_str_mv Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv Cycostat (R)
Oocyst excretion
Performance
Cycostat
Rabbit does
Coccidiosis
topic Cycostat (R)
Oocyst excretion
Performance
Cycostat
Rabbit does
Coccidiosis
description The present study was designed in order to evaluate the effi cacy and safety of Cycostat (R) 66G in the prevention and control of coccidiosis in breeding does after experimentally induced infection with common Eimeria spp. at the age of 18 wk. The inoculum was prepared based on faecal samples collected on farms in the Czech Republic. A total of 94 young and pregnant does were divided into 4 groups and enrolled in the study. The zootechnical, clinical and parasitological results of 2 control groups were compared, a non-infected non-treated (NI-NT) and an infected non-treated (I-NT), and 2 infected and dietary supplemented groups, with 50 (I-50) and 66 mg/kg (I-66) robenidine, respectively. Does in the I-NT group showed a significant drop in weight gain and feed intake during the fi rst 14 d after inoculation. No treatment related effects on the weight development of the does were observed, although does in the I-NT group always had approximately ± 200 g lower body weight. Litter size (live born) was not signifi cantly different at either the fi rst or second parturition and amounted to 9.0, 8.2, 10.1 and 9.8 (1st litter) and 11.3, 10.4, 10.1 and 11.0 (2nd litter) in NI-NT, I-NT, I-50 and I-66 does, respectively. At weaning, both in the 1st and 2nd cycle, the highest litter weight was obtained in the I-50 and I-66 groups. Litter weaning weight values for I-66 (litter 2) were higher but not significant (P=0.069) compared to the NI-NT litters. The lowest young mortality was also observed in the I-66 litters, both in the first and second cycles. Between 6 to 11 d after inoculation, the oocyst excretion of both supplemented groups was reduced by more than 90% in comparison to the I-NT. Supplementation with Cycostat (R) 66G diminished the excretion of E. flavescens and E. intestinalis, the most pathogenic species, by 100%. The excretion of E. magna was reduced by >90 and 100% for the I-50 and I-66 groups, respectively. The reduction in oocyst excretion of E. media was less pronounced. It was concluded that Cycostat (R) 66G supplemented in the feed at a concentration of 50 or 66mg/kg was able to prevent coccidiosis in breeding does after experimental inoculation.
publishDate 2010
dc.date.none.fl_str_mv 2010
2010-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/8432
url https://riunet.upv.es/handle/10251/8432
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reserva de todos los derechos
http://rightsstatements.org/vocab/InC/1.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reserva de todos los derechos
http://rightsstatements.org/vocab/InC/1.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv World Rabbit Science. ICTA. UPV
publisher.none.fl_str_mv World Rabbit Science. ICTA. UPV
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300719

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