Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years

Jara-Palomares, L.; Alfonso, M.; Maestre, A.; Jimenez, D.; Garcia-Bragado, F.; Font, C.; Reyes, R.L.; Blasco, L.H.; Vidal, G.; Otero, R.; Monreal, M.; Adarraga, M.ªD.; Aibar, M.Á.; Aibar, J.; Amado, C.; Arcelus, J.I.; Ballaz, A.; Barba, R.; Barrón, M.; Barrón-Andrés, B.; Bascuñana, J.; Blanco-Molina, Á.; Camón, A.M.; Cañas, I.; Carrasco, C.; Castro, J.; de Ancos, C.; Del Toro, J.; Demelo, P.; Díaz-Peromingo, J.A.; Díaz-Simón, R.; Falgá, C.; Farfán, A.I.; Fernández-Capitán, C.; del Carmen Fernández-Criado, M.; Fernández-Núñez, S.; Fidalgo, Á.; Font, L.; García, M.A.; García-Morillo, M.; García-Raso, A.; Gavín-Sebastián, O.; del Carmen Gayol, M.; Gil-Díaz, A.; Gómez, V.; Gómez-Cuervo, C.; González-Martínez, J.; Grau, E.; Gutiérrez, J.; Gutiérrez-González, S.; Iglesias, M.; Jaras, M.ªJ.; Jou, I.; Joya, M.D.; Lalueza, A.; Lima, J.; Llamas, P.; Lobo, J.L.; López-Jiménez, L.; López-Miguel, P.; López-Núñez, J.J.; López-Sáez, J.B.; Lorente, M.A.; Lorenzo, A.; Loring, M.; Madridano, O.; Marchena, P.J.; Martín, J.M.; Mellado, M.; Morales, M.ªV.; Nieto, M.L.; Nieto, J.A.; Núñez, M.J.; Olivares, M.C.; Pedrajas, J.M.; Pellejero, G.; Pérez-Rus, G.; Peris, M.ªL.; Porras, J.A.; Rivas, A.; Rodríguez-Dávila, M.ªÁ.; Adela Rodríguez-Hernández, A.; Rubio, C.M.; Ruiz-Artacho, P.; Ruiz-Ruiz, J.; Ruiz-Sada, P.; Sahuquillo, J.C.; Salazar, V.; Sampériz, Á.; Muñoz-Torrero, J.F.S.; Sancho, T.; Soler, S.; Suriñach, J.M.; Tapia, E.; Tolosa, C.; Torres, M.I.; Trujillo-Santos, J.; Uresandi, F.; Valle, R.; Villares, P.; Gutiérrez, P.; Vázquez, F.J.; Vilaseca, A.; Vanassche, T.; Vandenbriele, C.; Verhamme, P.; Hirmerova, J.; Malý, R.; Celis, G.; del Pozo, G.; Salgado, E.; Benzidia, I.; Bertoletti, L.; Bura-Riviere, A.; Debourdeau, P.; Farge-Bancel, D.; Hij, A.; Mahé, I.; Moustafa, F.; Schellong, S.; Braester, A.; Brenner, B.; Tzoran, I.; Sharif-Kashani, B.; Barillari, G.; Bilora, F.; Bortoluzzi, C.; Brandolin, B.; Bucherini, E.; Ciammaichella, M.; Dentali, F.; Di Micco, P.; Maida, R.; Mastroiacovo, D.; Mumoli, N.; Pace, F.; Parisi, R.; Pesavento, R.; Prandoni, P.; Quintavalla, R.; Rocci, A.; Romualdi, R.; Sinicalchi, C.; Tufano, A.; Visonà, A.; Hong, N.V.; Zalunardo, B.; Gibietis, V.; Kigitovica, D.; Skride, A.; Bosevski, M.; Bounameaux, H.; Mazzolai, L.; Caprini, J.A.; Bui, H.M.; Pham, K.Q.; Reis, A.

Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years

In young patients with acute pulmonary embolism (PE), the predictive value of currently available prognostic tools has not been evaluated. Our objective was to compare prognostic value of 7 available tools (GPS, PESI, sPESI, Prognostic Algorithm, PREP, shock index and RIETE) in patients aged <50...

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Autores:	Jara-Palomares, L., Alfonso, M., Maestre, A., Jimenez, D., Garcia-Bragado, F., Font, C., Reyes, R.L., Blasco, L.H., Vidal, G., Otero, R., Monreal, M., Adarraga, M.ªD., Aibar, M.Á., Aibar, J., Amado, C., Arcelus, J.I., Ballaz, A., Barba, R., Barrón, M., Barrón-Andrés, B., Bascuñana, J., Blanco-Molina, Á., Camón, A.M., Cañas, I., Carrasco, C., Castro, J., de Ancos, C., Del Toro, J., Demelo, P., Díaz-Peromingo, J.A., Díaz-Simón, R., Falgá, C., Farfán, A.I., Fernández-Capitán, C., del Carmen Fernández-Criado, M., Fernández-Núñez, S., Fidalgo, Á., Font, L., García, M.A., García-Morillo, M., García-Raso, A., Gavín-Sebastián, O., del Carmen Gayol, M., Gil-Díaz, A., Gómez, V., Gómez-Cuervo, C., González-Martínez, J., Grau, E., Gutiérrez, J., Gutiérrez-González, S., Iglesias, M., Jaras, M.ªJ., Jou, I., Joya, M.D., Lalueza, A., Lima, J., Llamas, P., Lobo, J.L., López-Jiménez, L., López-Miguel, P., López-Núñez, J.J., López-Sáez, J.B., Lorente, M.A., Lorenzo, A., Loring, M., Madridano, O., Marchena, P.J., Martín, J.M., Mellado, M., Morales, M.ªV., Nieto, M.L., Nieto, J.A., Núñez, M.J., Olivares, M.C., Pedrajas, J.M., Pellejero, G., Pérez-Rus, G., Peris, M.ªL., Porras, J.A., Rivas, A., Rodríguez-Dávila, M.ªÁ., Adela Rodríguez-Hernández, A., Rubio, C.M., Ruiz-Artacho, P., Ruiz-Ruiz, J., Ruiz-Sada, P., Sahuquillo, J.C., Salazar, V., Sampériz, Á., Muñoz-Torrero, J.F.S., Sancho, T., Soler, S., Suriñach, J.M., Tapia, E., Tolosa, C., Torres, M.I., Trujillo-Santos, J., Uresandi, F., Valle, R., Villares, P., Gutiérrez, P., Vázquez, F.J., Vilaseca, A., Vanassche, T., Vandenbriele, C., Verhamme, P., Hirmerova, J., Malý, R., Celis, G., del Pozo, G., Salgado, E., Benzidia, I., Bertoletti, L., Bura-Riviere, A., Debourdeau, P., Farge-Bancel, D., Hij, A., Mahé, I., Moustafa, F., Schellong, S., Braester, A., Brenner, B., Tzoran, I., Sharif-Kashani, B., Barillari, G., Bilora, F., Bortoluzzi, C., Brandolin, B., Bucherini, E., Ciammaichella, M., Dentali, F., Di Micco, P., Maida, R., Mastroiacovo, D., Mumoli, N., Pace, F., Parisi, R., Pesavento, R., Prandoni, P., Quintavalla, R., Rocci, A., Romualdi, R., Sinicalchi, C., Tufano, A., Visonà, A., Hong, N.V., Zalunardo, B., Gibietis, V., Kigitovica, D., Skride, A., Bosevski, M., Bounameaux, H., Mazzolai, L., Caprini, J.A., Bui, H.M., Pham, K.Q., Reis, A.
Formato:	artículo
Estado:	Versión publicada
Fecha de publicación:	2019
País:	España
Recursos:	Universidad de Zaragoza
Repositorio:	Zaguán. Repositorio Digital de la Universidad de Zaragoza
OAI Identifier:	oai:zaguan.unizar.es:97312
Acesso em linha:	http://zaguan.unizar.es/record/97312
Access Level:	acceso abierto

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oai_identifier_str	oai:zaguan.unizar.es:97312
network_acronym_str	ES
network_name_str	España
repository_id_str
spelling	Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 yearsJara-Palomares, L.Alfonso, M.Maestre, A.Jimenez, D.Garcia-Bragado, F.Font, C.Reyes, R.L.Blasco, L.H.Vidal, G.Otero, R.Monreal, M.Adarraga, M.ªD.Aibar, M.Á.Aibar, J.Amado, C.Arcelus, J.I.Ballaz, A.Barba, R.Barrón, M.Barrón-Andrés, B.Bascuñana, J.Blanco-Molina, Á.Camón, A.M.Cañas, I.Carrasco, C.Castro, J.de Ancos, C.Del Toro, J.Demelo, P.Díaz-Peromingo, J.A.Díaz-Simón, R.Falgá, C.Farfán, A.I.Fernández-Capitán, C.del Carmen Fernández-Criado, M.Fernández-Núñez, S.Fidalgo, Á.Font, L.García, M.A.García-Morillo, M.García-Raso, A.Gavín-Sebastián, O.del Carmen Gayol, M.Gil-Díaz, A.Gómez, V.Gómez-Cuervo, C.González-Martínez, J.Grau, E.Gutiérrez, J.Gutiérrez-González, S.Iglesias, M.Jaras, M.ªJ.Jou, I.Joya, M.D.Lalueza, A.Lima, J.Llamas, P.Lobo, J.L.López-Jiménez, L.López-Miguel, P.López-Núñez, J.J.López-Sáez, J.B.Lorente, M.A.Lorenzo, A.Loring, M.Madridano, O.Marchena, P.J.Martín, J.M.Mellado, M.Morales, M.ªV.Nieto, M.L.Nieto, J.A.Núñez, M.J.Olivares, M.C.Pedrajas, J.M.Pellejero, G.Pérez-Rus, G.Peris, M.ªL.Porras, J.A.Rivas, A.Rodríguez-Dávila, M.ªÁ.Adela Rodríguez-Hernández, A.Rubio, C.M.Ruiz-Artacho, P.Ruiz-Ruiz, J.Ruiz-Sada, P.Sahuquillo, J.C.Salazar, V.Sampériz, Á.Muñoz-Torrero, J.F.S.Sancho, T.Soler, S.Suriñach, J.M.Tapia, E.Tolosa, C.Torres, M.I.Trujillo-Santos, J.Uresandi, F.Valle, R.Villares, P.Gutiérrez, P.Vázquez, F.J.Vilaseca, A.Vanassche, T.Vandenbriele, C.Verhamme, P.Hirmerova, J.Malý, R.Celis, G.del Pozo, G.Salgado, E.Benzidia, I.Bertoletti, L.Bura-Riviere, A.Debourdeau, P.Farge-Bancel, D.Hij, A.Mahé, I.Moustafa, F.Schellong, S.Braester, A.Brenner, B.Tzoran, I.Sharif-Kashani, B.Barillari, G.Bilora, F.Bortoluzzi, C.Brandolin, B.Bucherini, E.Ciammaichella, M.Dentali, F.Di Micco, P.Maida, R.Mastroiacovo, D.Mumoli, N.Pace, F.Parisi, R.Pesavento, R.Prandoni, P.Quintavalla, R.Rocci, A.Romualdi, R.Sinicalchi, C.Tufano, A.Visonà, A.Hong, N.V.Zalunardo, B.Gibietis, V.Kigitovica, D.Skride, A.Bosevski, M.Bounameaux, H.Mazzolai, L.Caprini, J.A.Bui, H.M.Pham, K.Q.Reis, A.In young patients with acute pulmonary embolism (PE), the predictive value of currently available prognostic tools has not been evaluated. Our objective was to compare prognostic value of 7 available tools (GPS, PESI, sPESI, Prognostic Algorithm, PREP, shock index and RIETE) in patients aged <50 years. We used the RIETE database, including PE patients from 2001 to 2017. The major outcome was 30-day all-cause mortality. Of 34, 651 patients with acute PE, 5, 822 (17%) were aged <50 years. Of these, 83 (1.4%) died during the first 30 days. Number of patients deemed low risk with tools was: PREP (95.9%), GPS (89.6%), PESI (87.2%), Shock index (70.9%), sPESI (59.4%), Prognostic algorithm (58%) and RIETE score (48.6%). The tools with a highest sensitivity were: Prognostic Algorithm (91.6%; 95% CI: 85.6–97.5), RIETE score (90.4%; 95%CI: 84.0–96.7) and sPESI (88%; 95% CI: 81–95). The RIETE, Prognostic Algorithm and sPESI scores obtained the highest overall sensitivity estimates for also predicting 7- and 90-day all-cause mortality, 30-day PE-related mortality, 30-day major bleeding and 30-day VTE recurrences. The proportion of low-risk patients who died within the first 30 days was lowest using the Prognostic Algorithm (0.2%), RIETE (0.3%) or sPESI (0.3%) scores. In PE patients less 50 years, 30-day mortality was low. Although sPESI, RIETE and Prognostic Algorithm scores were the most sensitive tools to identify patients at low risk to die, other tools should be evaluated in this population to obtain more efficient results.2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://zaguan.unizar.es/record/97312reponame:Zaguán. Repositorio Digital de la Universidad de Zaragozainstname:Universidad de ZaragozaInglésinfo:eu-repo/semantics/openAccessoai:zaguan.unizar.es:973122026-05-29T13:59:51Z
dc.title.none.fl_str_mv	Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years
title	Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years
spellingShingle	Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years Jara-Palomares, L.
title_short	Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years
title_full	Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years
title_fullStr	Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years
title_full_unstemmed	Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years
title_sort	Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years
dc.creator.none.fl_str_mv	Jara-Palomares, L. Alfonso, M. Maestre, A. Jimenez, D. Garcia-Bragado, F. Font, C. Reyes, R.L. Blasco, L.H. Vidal, G. Otero, R. Monreal, M. Adarraga, M.ªD. Aibar, M.Á. Aibar, J. Amado, C. Arcelus, J.I. Ballaz, A. Barba, R. Barrón, M. Barrón-Andrés, B. Bascuñana, J. Blanco-Molina, Á. Camón, A.M. Cañas, I. Carrasco, C. Castro, J. de Ancos, C. Del Toro, J. Demelo, P. Díaz-Peromingo, J.A. Díaz-Simón, R. Falgá, C. Farfán, A.I. Fernández-Capitán, C. del Carmen Fernández-Criado, M. Fernández-Núñez, S. Fidalgo, Á. Font, L. García, M.A. García-Morillo, M. García-Raso, A. Gavín-Sebastián, O. del Carmen Gayol, M. Gil-Díaz, A. Gómez, V. Gómez-Cuervo, C. González-Martínez, J. Grau, E. Gutiérrez, J. Gutiérrez-González, S. Iglesias, M. Jaras, M.ªJ. Jou, I. Joya, M.D. Lalueza, A. Lima, J. Llamas, P. Lobo, J.L. López-Jiménez, L. López-Miguel, P. López-Núñez, J.J. López-Sáez, J.B. Lorente, M.A. Lorenzo, A. Loring, M. Madridano, O. Marchena, P.J. Martín, J.M. Mellado, M. Morales, M.ªV. Nieto, M.L. Nieto, J.A. Núñez, M.J. Olivares, M.C. Pedrajas, J.M. Pellejero, G. Pérez-Rus, G. Peris, M.ªL. Porras, J.A. Rivas, A. Rodríguez-Dávila, M.ªÁ. Adela Rodríguez-Hernández, A. Rubio, C.M. Ruiz-Artacho, P. Ruiz-Ruiz, J. Ruiz-Sada, P. Sahuquillo, J.C. Salazar, V. Sampériz, Á. Muñoz-Torrero, J.F.S. Sancho, T. Soler, S. Suriñach, J.M. Tapia, E. Tolosa, C. Torres, M.I. Trujillo-Santos, J. Uresandi, F. Valle, R. Villares, P. Gutiérrez, P. Vázquez, F.J. Vilaseca, A. Vanassche, T. Vandenbriele, C. Verhamme, P. Hirmerova, J. Malý, R. Celis, G. del Pozo, G. Salgado, E. Benzidia, I. Bertoletti, L. Bura-Riviere, A. Debourdeau, P. Farge-Bancel, D. Hij, A. Mahé, I. Moustafa, F. Schellong, S. Braester, A. Brenner, B. Tzoran, I. Sharif-Kashani, B. Barillari, G. Bilora, F. Bortoluzzi, C. Brandolin, B. Bucherini, E. Ciammaichella, M. Dentali, F. Di Micco, P. Maida, R. Mastroiacovo, D. Mumoli, N. Pace, F. Parisi, R. Pesavento, R. Prandoni, P. Quintavalla, R. Rocci, A. Romualdi, R. Sinicalchi, C. Tufano, A. Visonà, A. Hong, N.V. Zalunardo, B. Gibietis, V. Kigitovica, D. Skride, A. Bosevski, M. Bounameaux, H. Mazzolai, L. Caprini, J.A. Bui, H.M. Pham, K.Q. Reis, A.
author	Jara-Palomares, L.
author_facet	Jara-Palomares, L. Alfonso, M. Maestre, A. Jimenez, D. Garcia-Bragado, F. Font, C. Reyes, R.L. Blasco, L.H. Vidal, G. Otero, R. Monreal, M. Adarraga, M.ªD. Aibar, M.Á. Aibar, J. Amado, C. Arcelus, J.I. Ballaz, A. Barba, R. Barrón, M. Barrón-Andrés, B. Bascuñana, J. Blanco-Molina, Á. Camón, A.M. Cañas, I. Carrasco, C. Castro, J. de Ancos, C. Del Toro, J. Demelo, P. Díaz-Peromingo, J.A. Díaz-Simón, R. Falgá, C. Farfán, A.I. Fernández-Capitán, C. del Carmen Fernández-Criado, M. Fernández-Núñez, S. Fidalgo, Á. Font, L. García, M.A. García-Morillo, M. García-Raso, A. Gavín-Sebastián, O. del Carmen Gayol, M. Gil-Díaz, A. Gómez, V. Gómez-Cuervo, C. González-Martínez, J. Grau, E. Gutiérrez, J. Gutiérrez-González, S. Iglesias, M. Jaras, M.ªJ. Jou, I. Joya, M.D. Lalueza, A. Lima, J. Llamas, P. Lobo, J.L. López-Jiménez, L. López-Miguel, P. López-Núñez, J.J. López-Sáez, J.B. Lorente, M.A. Lorenzo, A. Loring, M. Madridano, O. Marchena, P.J. Martín, J.M. Mellado, M. Morales, M.ªV. Nieto, M.L. Nieto, J.A. Núñez, M.J. Olivares, M.C. Pedrajas, J.M. Pellejero, G. Pérez-Rus, G. Peris, M.ªL. Porras, J.A. Rivas, A. Rodríguez-Dávila, M.ªÁ. Adela Rodríguez-Hernández, A. Rubio, C.M. Ruiz-Artacho, P. Ruiz-Ruiz, J. Ruiz-Sada, P. Sahuquillo, J.C. Salazar, V. Sampériz, Á. Muñoz-Torrero, J.F.S. Sancho, T. Soler, S. Suriñach, J.M. Tapia, E. Tolosa, C. Torres, M.I. Trujillo-Santos, J. Uresandi, F. Valle, R. Villares, P. Gutiérrez, P. Vázquez, F.J. Vilaseca, A. Vanassche, T. Vandenbriele, C. Verhamme, P. Hirmerova, J. Malý, R. Celis, G. del Pozo, G. Salgado, E. Benzidia, I. Bertoletti, L. Bura-Riviere, A. Debourdeau, P. Farge-Bancel, D. Hij, A. Mahé, I. Moustafa, F. Schellong, S. Braester, A. Brenner, B. Tzoran, I. Sharif-Kashani, B. Barillari, G. Bilora, F. Bortoluzzi, C. Brandolin, B. Bucherini, E. Ciammaichella, M. Dentali, F. Di Micco, P. Maida, R. Mastroiacovo, D. Mumoli, N. Pace, F. Parisi, R. Pesavento, R. Prandoni, P. Quintavalla, R. Rocci, A. Romualdi, R. Sinicalchi, C. Tufano, A. Visonà, A. Hong, N.V. Zalunardo, B. Gibietis, V. Kigitovica, D. Skride, A. Bosevski, M. Bounameaux, H. Mazzolai, L. Caprini, J.A. Bui, H.M. Pham, K.Q. Reis, A.
author_role	author
author2	Alfonso, M. Maestre, A. Jimenez, D. Garcia-Bragado, F. Font, C. Reyes, R.L. Blasco, L.H. Vidal, G. Otero, R. Monreal, M. Adarraga, M.ªD. Aibar, M.Á. Aibar, J. Amado, C. Arcelus, J.I. Ballaz, A. Barba, R. Barrón, M. Barrón-Andrés, B. Bascuñana, J. Blanco-Molina, Á. Camón, A.M. Cañas, I. Carrasco, C. Castro, J. de Ancos, C. Del Toro, J. Demelo, P. Díaz-Peromingo, J.A. Díaz-Simón, R. Falgá, C. Farfán, A.I. Fernández-Capitán, C. del Carmen Fernández-Criado, M. Fernández-Núñez, S. Fidalgo, Á. Font, L. García, M.A. García-Morillo, M. García-Raso, A. Gavín-Sebastián, O. del Carmen Gayol, M. Gil-Díaz, A. Gómez, V. Gómez-Cuervo, C. González-Martínez, J. Grau, E. Gutiérrez, J. Gutiérrez-González, S. Iglesias, M. Jaras, M.ªJ. Jou, I. Joya, M.D. Lalueza, A. Lima, J. Llamas, P. Lobo, J.L. López-Jiménez, L. López-Miguel, P. López-Núñez, J.J. López-Sáez, J.B. Lorente, M.A. Lorenzo, A. Loring, M. Madridano, O. Marchena, P.J. Martín, J.M. Mellado, M. Morales, M.ªV. Nieto, M.L. Nieto, J.A. Núñez, M.J. Olivares, M.C. Pedrajas, J.M. Pellejero, G. Pérez-Rus, G. Peris, M.ªL. Porras, J.A. Rivas, A. Rodríguez-Dávila, M.ªÁ. Adela Rodríguez-Hernández, A. Rubio, C.M. Ruiz-Artacho, P. Ruiz-Ruiz, J. Ruiz-Sada, P. Sahuquillo, J.C. Salazar, V. Sampériz, Á. Muñoz-Torrero, J.F.S. Sancho, T. Soler, S. Suriñach, J.M. Tapia, E. Tolosa, C. Torres, M.I. Trujillo-Santos, J. Uresandi, F. Valle, R. Villares, P. Gutiérrez, P. Vázquez, F.J. Vilaseca, A. Vanassche, T. Vandenbriele, C. Verhamme, P. Hirmerova, J. Malý, R. Celis, G. del Pozo, G. Salgado, E. Benzidia, I. Bertoletti, L. Bura-Riviere, A. Debourdeau, P. Farge-Bancel, D. Hij, A. Mahé, I. Moustafa, F. Schellong, S. Braester, A. Brenner, B. Tzoran, I. Sharif-Kashani, B. Barillari, G. Bilora, F. Bortoluzzi, C. Brandolin, B. Bucherini, E. Ciammaichella, M. Dentali, F. Di Micco, P. Maida, R. Mastroiacovo, D. Mumoli, N. Pace, F. Parisi, R. Pesavento, R. Prandoni, P. Quintavalla, R. Rocci, A. Romualdi, R. Sinicalchi, C. Tufano, A. Visonà, A. Hong, N.V. Zalunardo, B. Gibietis, V. Kigitovica, D. Skride, A. Bosevski, M. Bounameaux, H. Mazzolai, L. Caprini, J.A. Bui, H.M. Pham, K.Q. Reis, A.
author2_role	author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author
description	In young patients with acute pulmonary embolism (PE), the predictive value of currently available prognostic tools has not been evaluated. Our objective was to compare prognostic value of 7 available tools (GPS, PESI, sPESI, Prognostic Algorithm, PREP, shock index and RIETE) in patients aged <50 years. We used the RIETE database, including PE patients from 2001 to 2017. The major outcome was 30-day all-cause mortality. Of 34, 651 patients with acute PE, 5, 822 (17%) were aged <50 years. Of these, 83 (1.4%) died during the first 30 days. Number of patients deemed low risk with tools was: PREP (95.9%), GPS (89.6%), PESI (87.2%), Shock index (70.9%), sPESI (59.4%), Prognostic algorithm (58%) and RIETE score (48.6%). The tools with a highest sensitivity were: Prognostic Algorithm (91.6%; 95% CI: 85.6–97.5), RIETE score (90.4%; 95%CI: 84.0–96.7) and sPESI (88%; 95% CI: 81–95). The RIETE, Prognostic Algorithm and sPESI scores obtained the highest overall sensitivity estimates for also predicting 7- and 90-day all-cause mortality, 30-day PE-related mortality, 30-day major bleeding and 30-day VTE recurrences. The proportion of low-risk patients who died within the first 30 days was lowest using the Prognostic Algorithm (0.2%), RIETE (0.3%) or sPESI (0.3%) scores. In PE patients less 50 years, 30-day mortality was low. Although sPESI, RIETE and Prognostic Algorithm scores were the most sensitive tools to identify patients at low risk to die, other tools should be evaluated in this population to obtain more efficient results.
publishDate	2019
dc.date.none.fl_str_mv	2019
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	http://zaguan.unizar.es/record/97312
url	http://zaguan.unizar.es/record/97312
dc.language.none.fl_str_mv	Inglés
language_invalid_str_mv	Inglés
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.format.none.fl_str_mv	application/pdf
dc.publisher.none.fl_str_mv
publisher.none.fl_str_mv
dc.source.none.fl_str_mv	reponame:Zaguán. Repositorio Digital de la Universidad de Zaragoza instname:Universidad de Zaragoza
instname_str	Universidad de Zaragoza
reponame_str	Zaguán. Repositorio Digital de la Universidad de Zaragoza
collection	Zaguán. Repositorio Digital de la Universidad de Zaragoza
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_	1869404947355795456
score	15,301603

Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years

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