Structured parametric epidemic models

A stage-structured model for a theoretical epidemic process that incorporates immature, susceptible and infectious individuals in independent stages is formulated. In this analysis, an input interpreted as a birth function is considered. The structural identifiability is studied using the Markov par...

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Detalles Bibliográficos
Autores: Cantó Colomina, Begoña|||0000-0002-9837-3926, Coll, Carmen|||0000-0002-6487-3922, Sánchez, Elena|||0000-0002-0972-6612
Tipo de recurso: artículo
Fecha de publicación:2014
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/50136
Acceso en línea:https://riunet.upv.es/handle/10251/50136
Access Level:acceso abierto
Palabra clave:Beverton-Holt function
Basic reproduction number
Equilibrium
Identifiability
Epidemic model
MATEMATICA APLICADA
Descripción
Sumario:A stage-structured model for a theoretical epidemic process that incorporates immature, susceptible and infectious individuals in independent stages is formulated. In this analysis, an input interpreted as a birth function is considered. The structural identifiability is studied using the Markov parameters. Then, the unknown parameters are uniquely determined by the output structure corresponding to an observation of infection. Two different birth functions are considered: the linear case and the Beverton-Holt type to analyse the structured epidemic model. Some conditions on the parameters to obtain non-zero disease-free equilibrium points are given. The identifiability of the parameters allows us to determine uniquely the basic reproduction number Script capital R-0 and the stability of the model in the equilibrium is studied using Script capital R-0 in terms of the model parameters.