Modeling breast tumor growth by a randomized logistic model: A computational approach to treat uncertainties via probability densities

[EN] We consider a randomized discrete logistic equation to describe the dynamics of breast tumor volume. We propose a method, that takes advantage of the principle of maximum entropy, to assign reliable distributions to model inputs (initial condition and coefficients) and sample data, respectively...

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Detalles Bibliográficos
Autores: Burgos-Simon, Clara|||0000-0001-6385-4263, Cortés, J.-C.|||0000-0002-6528-2155, Villanueva Micó, Rafael Jacinto|||0000-0002-0131-0532, Martínez-Rodríguez, David
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/161047
Acceso en línea:https://riunet.upv.es/handle/10251/161047
Access Level:acceso abierto
Palabra clave:Maximum entropy principle
Computational model fitting
Volume tumor growth
Uncertainty treatment
MATEMATICA APLICADA
Descripción
Sumario:[EN] We consider a randomized discrete logistic equation to describe the dynamics of breast tumor volume. We propose a method, that takes advantage of the principle of maximum entropy, to assign reliable distributions to model inputs (initial condition and coefficients) and sample data, respectively. Since the distributions of coefficients depend on certain parameters, we design a computational procedure to determine the above mentioned parameters using the information of the probabilistic distributions. The proposed method is successfully applied to model the breast tumor volume using real data. The approach seems to be flexible enough to be adapted to other stochastic models in future contributions.