Textile antenna-sensor for In vitro diagnostics of diabetes

In this paper, a feasibility study of a microwave antenna-based sensor is proposed for in vitro experiments for monitoring blood glucose levels. The proposed device consists of a square-ring incorporated within a fully textile monopole antenna to absorb and sense different glucose concentrations, co...

Descripción completa

Detalles Bibliográficos
Autores: El Gharbi, Mariam|||0000-0002-6681-3907, Fernández García, Raúl|||0000-0002-4030-7256, Gil Galí, Ignacio|||0000-0002-7175-5756
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/359911
Acceso en línea:https://hdl.handle.net/2117/359911
https://dx.doi.org/10.3390/electronics10131570
Access Level:acceso abierto
Palabra clave:Electrònica--Mesuraments--Aparells i instruments
Medical electronics
Antenna-sensor
Frequency shift
Glucose detection
Microwave sensing
Sensitivity
Textile monopole antenna
Electric measurements - Instruments
Electrònica mèdica
Àrees temàtiques de la UPC::Enginyeria electrònica::Instrumentació i mesura::Sensors i actuadors
Àrees temàtiques de la UPC::Enginyeria electrònica
Descripción
Sumario:In this paper, a feasibility study of a microwave antenna-based sensor is proposed for in vitro experiments for monitoring blood glucose levels. The proposed device consists of a square-ring incorporated within a fully textile monopole antenna to absorb and sense different glucose concentrations, covering patients with different diabetic conditions. The designed antenna-sensor is optimized to operate at 2.4 GHz. The sensing principle is based on the resonance frequency shift of the reflection response of the antenna-based sensor under different glucose levels. The experiments were carried out with blood mimicking by means of aqueous solutions, using D(+)- glucose/water in different concentrations for various diabetic conditions of type-2 diabetes. The performance of the embroidered antenna-based sensor is characterized and validated using a convenient setup for in vitro measurements. The results demonstrated the ability of the proposed antenna-based sensor to cover all the glucose levels of the diabetes range, including hypoglycemia (10–70 mg/dL), normoglycemia (80–110 mg/dL) and hyperglycemia (130–190 mg/dL) with a sensitivity of 350 kHz/(mg/dL). Besides its ability to detect different glucose concentrations of various diabetic conditions, the proposed antenna-sensor presents diverse features such as a simplistic design, compact size, wearability and low cost. The proposed textile device demonstrates a proof of concept for efficient in vitro blood glucose level measurements and diagnostics of diabetes.