Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapy

Oral cavity cancer is the most frequent malignancy of the head and neck. Unfortunately, despite educational interventions for prevention and early diagnosis, oral cancer patients are often diagnosed in advanced stages associated with poor prognosis and life expectancy. Therefore, there is an urgent...

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Autores: Rapado González, Óscar, López López, Rafael, López Cedrún, José Luis, Triana Martínez, Gabriel, Muinelo Romay, Laura, Suárez Cunqueiro, María Mercedes
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/21251
Acceso en línea:http://hdl.handle.net/10347/21251
Access Level:acceso abierto
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spelling Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapyRapado González, ÓscarLópez López, RafaelLópez Cedrún, José LuisTriana Martínez, GabrielMuinelo Romay, LauraSuárez Cunqueiro, María MercedesOral cavity cancer is the most frequent malignancy of the head and neck. Unfortunately, despite educational interventions for prevention and early diagnosis, oral cancer patients are often diagnosed in advanced stages associated with poor prognosis and life expectancy. Therefore, there is an urgent need to find noninvasive biomarkers to improve early detection of this tumor. Liquid biopsy has emerged as a valuable tool in medical oncology which provides new horizons for improving clinical decision making. Notably, cell-free microRNAs (miRNAs), a class of short non-coding RNAs, are emerging as novel noninvasive cancer biomarkers. Here, we provide an overview of the potential clinical application of cell-free miRNAs as diagnostic, prognostic, and therapeutic biomarkers in oral cancerMDPIUniversidade de Santiago de Compostela. Departamento de Cirurxía e Especialidades Médico-Cirúrxicas20192019-01-0120192019-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10347/21251reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostelainstname:Universidad de Santiago de Compostela (USC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:minerva.usc.gal:10347/212512026-06-15T12:47:27Z
dc.title.none.fl_str_mv Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapy
title Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapy
spellingShingle Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapy
Rapado González, Óscar
title_short Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapy
title_full Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapy
title_fullStr Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapy
title_full_unstemmed Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapy
title_sort Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapy
dc.creator.none.fl_str_mv Rapado González, Óscar
López López, Rafael
López Cedrún, José Luis
Triana Martínez, Gabriel
Muinelo Romay, Laura
Suárez Cunqueiro, María Mercedes
author Rapado González, Óscar
author_facet Rapado González, Óscar
López López, Rafael
López Cedrún, José Luis
Triana Martínez, Gabriel
Muinelo Romay, Laura
Suárez Cunqueiro, María Mercedes
author_role author
author2 López López, Rafael
López Cedrún, José Luis
Triana Martínez, Gabriel
Muinelo Romay, Laura
Suárez Cunqueiro, María Mercedes
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de Santiago de Compostela. Departamento de Cirurxía e Especialidades Médico-Cirúrxicas
description Oral cavity cancer is the most frequent malignancy of the head and neck. Unfortunately, despite educational interventions for prevention and early diagnosis, oral cancer patients are often diagnosed in advanced stages associated with poor prognosis and life expectancy. Therefore, there is an urgent need to find noninvasive biomarkers to improve early detection of this tumor. Liquid biopsy has emerged as a valuable tool in medical oncology which provides new horizons for improving clinical decision making. Notably, cell-free microRNAs (miRNAs), a class of short non-coding RNAs, are emerging as novel noninvasive cancer biomarkers. Here, we provide an overview of the potential clinical application of cell-free miRNAs as diagnostic, prognostic, and therapeutic biomarkers in oral cancer
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01
2019
2019-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10347/21251
url http://hdl.handle.net/10347/21251
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname:Universidad de Santiago de Compostela (USC)
instname_str Universidad de Santiago de Compostela (USC)
reponame_str Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
collection Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
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