BioExcel Building Blocks, a software library for interoperable biomolecular simulation workflows.

In the recent years, the improvement of software and hardware performance has made biomolecular simulations a mature tool for the study of biological processes. Simulation length and the size and complexity of the analyzed systems make simulations both complementary and compatible with other bioinfo...

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Detalles Bibliográficos
Autores: Andrio, Pau, Hospital Gasch, Adam, Conejero, Javier, Jordá, Luis, Del Pino, Marc, Codo, Laia, Soiland-Reyes, Stian, Goble, Carole, Lezzi, Daniele, Badia, Rosa M., Orozco López, Modesto, Gelpí Buchaca, Josep Lluís
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/162518
Acceso en línea:https://hdl.handle.net/2445/162518
Access Level:acceso abierto
Palabra clave:Biomolècules
Mètodes de simulació
Ontologies (Informàtica)
Biomolecules
Simulation methods
Ontologies (Information retrieval)
Descripción
Sumario:In the recent years, the improvement of software and hardware performance has made biomolecular simulations a mature tool for the study of biological processes. Simulation length and the size and complexity of the analyzed systems make simulations both complementary and compatible with other bioinformatics disciplines. However, the characteristics of the software packages used for simulation have prevented the adoption of the technologies accepted in other bioinformatics fields like automated deployment systems, workflow orchestration, or the use of software containers. We present here a comprehensive exercise to bring biomolecular simulations to the "bioinformatics way of working". The exercise has led to the development of the BioExcel Building Blocks (BioBB) library. BioBB's are built as Python wrappers to provide an interoperable architecture. BioBB's have been integrated in a chain of usual software management tools to generate data ontologies, documentation, installation packages, software containers and ways of integration with workflow managers, that make them usable in most computational environments.