Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer

The present study sought to evaluate the usefulness of EBUS-TBNA in the diagnosis of locoregional recurrence of lung cancer in a cohort of lung cancer patients who were previously treated surgically, and describe our initial experience of EUS-B-FNA in this clinical scenario. We retrospectively studi...

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Autores: Sanz-Santos, José|||0000-0001-8354-414X, Serra Mitjà, Pere|||0000-0002-6125-7358, Andreo García, Felipe|||0000-0003-4842-9597, Torky, Mohamed, Centeno, Carmen, Morán, Teresa, Carcereny, Enric|||0000-0001-5235-5602, Fernández Araujo, Esther, García-Reina, Samuel, Ruiz Manzano, Juan|||0000-0001-7213-7346
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:186162
Acceso en línea:https://ddd.uab.cat/record/186162
https://dx.doi.org/urn:doi:10.1186/s12890-017-0388-4
Access Level:acceso abierto
Palabra clave:Lung cancer
Recurrence
Surgically-treated
Endobronchial Ultrasound
Transbronchial needle aspiration
Endoscopic ultrasound
Fine needle aspiration
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spelling Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancerSanz-Santos, José|||0000-0001-8354-414XSerra Mitjà, Pere|||0000-0002-6125-7358Andreo García, Felipe|||0000-0003-4842-9597Torky, MohamedCenteno, CarmenMorán, TeresaCarcereny, Enric|||0000-0001-5235-5602Fernández Araujo, EstherGarcía-Reina, SamuelRuiz Manzano, Juan|||0000-0001-7213-7346Lung cancerRecurrenceSurgically-treatedEndobronchial UltrasoundTransbronchial needle aspirationEndoscopic ultrasoundFine needle aspirationThe present study sought to evaluate the usefulness of EBUS-TBNA in the diagnosis of locoregional recurrence of lung cancer in a cohort of lung cancer patients who were previously treated surgically, and describe our initial experience of EUS-B-FNA in this clinical scenario. We retrospectively studied the clinical records of all patients with a previous surgically-treated lung cancer who were referred to our bronchoscopy unit after suspicion of locoregional recurrence. The diagnostic sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and overall accuracy of EBUS-TBNA for the diagnosis of locoregional recurrence were evaluated. Seventy-three patients were included. EBUS-TBNA confirmed malignancy in 40 patients: 34 confirmed to have locoregional recurrence, six had metachronous tumours. Of the 33 patients with non-malignant EBUS-TBNA; 2 had specific non-malignant diseases, 26 underwent radiological follow up and 5 patients underwent surgery. Of the 26 patients who had radiological follow up; 18 remained stable, three presented thoracic radiological progression and 5 presented extrathoracic progression. Of the 5 patients who underwent surgery; 3 had metachronous tumours, one confirmed to be a true negative and one presented nodal invasion. Seven patients underwent EUS-B-FNA, four of them confirmed to have recurrence. The sensitivity, specificity, NPV, PPV and overall accuracy of EBUS-TBNA for the diagnosis of locoregional recurrence were 80.9, 100, 69.2, 100 and 86.6% respectively. EBUS-TBNA is an accurate procedure for the diagnosis of locoregional recurrence of surgically-treated lung cancer. EUS-B-FNA combined with EBUS-TBNA broads the diagnostic yield of EBUS-TBNA alone. 22017-01-0120172017-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/186162https://dx.doi.org/urn:doi:10.1186/s12890-017-0388-4reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:1861622026-06-06T12:50:31Z
dc.title.none.fl_str_mv Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer
title Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer
spellingShingle Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer
Sanz-Santos, José|||0000-0001-8354-414X
Lung cancer
Recurrence
Surgically-treated
Endobronchial Ultrasound
Transbronchial needle aspiration
Endoscopic ultrasound
Fine needle aspiration
title_short Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer
title_full Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer
title_fullStr Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer
title_full_unstemmed Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer
title_sort Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer
dc.creator.none.fl_str_mv Sanz-Santos, José|||0000-0001-8354-414X
Serra Mitjà, Pere|||0000-0002-6125-7358
Andreo García, Felipe|||0000-0003-4842-9597
Torky, Mohamed
Centeno, Carmen
Morán, Teresa
Carcereny, Enric|||0000-0001-5235-5602
Fernández Araujo, Esther
García-Reina, Samuel
Ruiz Manzano, Juan|||0000-0001-7213-7346
author Sanz-Santos, José|||0000-0001-8354-414X
author_facet Sanz-Santos, José|||0000-0001-8354-414X
Serra Mitjà, Pere|||0000-0002-6125-7358
Andreo García, Felipe|||0000-0003-4842-9597
Torky, Mohamed
Centeno, Carmen
Morán, Teresa
Carcereny, Enric|||0000-0001-5235-5602
Fernández Araujo, Esther
García-Reina, Samuel
Ruiz Manzano, Juan|||0000-0001-7213-7346
author_role author
author2 Serra Mitjà, Pere|||0000-0002-6125-7358
Andreo García, Felipe|||0000-0003-4842-9597
Torky, Mohamed
Centeno, Carmen
Morán, Teresa
Carcereny, Enric|||0000-0001-5235-5602
Fernández Araujo, Esther
García-Reina, Samuel
Ruiz Manzano, Juan|||0000-0001-7213-7346
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Lung cancer
Recurrence
Surgically-treated
Endobronchial Ultrasound
Transbronchial needle aspiration
Endoscopic ultrasound
Fine needle aspiration
topic Lung cancer
Recurrence
Surgically-treated
Endobronchial Ultrasound
Transbronchial needle aspiration
Endoscopic ultrasound
Fine needle aspiration
description The present study sought to evaluate the usefulness of EBUS-TBNA in the diagnosis of locoregional recurrence of lung cancer in a cohort of lung cancer patients who were previously treated surgically, and describe our initial experience of EUS-B-FNA in this clinical scenario. We retrospectively studied the clinical records of all patients with a previous surgically-treated lung cancer who were referred to our bronchoscopy unit after suspicion of locoregional recurrence. The diagnostic sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and overall accuracy of EBUS-TBNA for the diagnosis of locoregional recurrence were evaluated. Seventy-three patients were included. EBUS-TBNA confirmed malignancy in 40 patients: 34 confirmed to have locoregional recurrence, six had metachronous tumours. Of the 33 patients with non-malignant EBUS-TBNA; 2 had specific non-malignant diseases, 26 underwent radiological follow up and 5 patients underwent surgery. Of the 26 patients who had radiological follow up; 18 remained stable, three presented thoracic radiological progression and 5 presented extrathoracic progression. Of the 5 patients who underwent surgery; 3 had metachronous tumours, one confirmed to be a true negative and one presented nodal invasion. Seven patients underwent EUS-B-FNA, four of them confirmed to have recurrence. The sensitivity, specificity, NPV, PPV and overall accuracy of EBUS-TBNA for the diagnosis of locoregional recurrence were 80.9, 100, 69.2, 100 and 86.6% respectively. EBUS-TBNA is an accurate procedure for the diagnosis of locoregional recurrence of surgically-treated lung cancer. EUS-B-FNA combined with EBUS-TBNA broads the diagnostic yield of EBUS-TBNA alone.
publishDate 2017
dc.date.none.fl_str_mv 2
2017-01-01
2017
2017-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/186162
https://dx.doi.org/urn:doi:10.1186/s12890-017-0388-4
url https://ddd.uab.cat/record/186162
https://dx.doi.org/urn:doi:10.1186/s12890-017-0388-4
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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