Near-infrared lifetime nanothermometry detects microwave-induced brain heating

In modern environments, the brain is continuously exposed to numerous external stimuli, including the microwave radiation used in telecommunication technologies. It has been suggested that the absorption of this radiation by brain tissue can induce local heating. Because brain temperature influences...

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Detalles Bibliográficos
Autores: Liyan Ming, José Lifante, Ginés Lifante Pedrola, Daniel Ortega, Erving Ximendes, Riccardo Marin, Julio Ramiro Bargueño, Daniel Jaque, Rubio Retama, Benito Jorge, Zabala Gutiérrez, Irene
Tipo de recurso: artículo
Fecha de publicación:0025
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/131036
Acceso en línea:https://hdl.handle.net/20.500.14352/131036
Access Level:acceso abierto
Palabra clave:544
Heating
Luminescence lifetime
Luminescence thermometry
Microwave radiation
Thermal effects
Química física (Química)
23 Química
22 Física
Descripción
Sumario:In modern environments, the brain is continuously exposed to numerous external stimuli, including the microwave radiation used in telecommunication technologies. It has been suggested that the absorption of this radiation by brain tissue can induce local heating. Because brain temperature influences neural activity, metabolism, and overall brain function, microwave-induced heating raises concerns over the safety of such technologies. Proper evaluation of the risks associated with microwave-based technologies thus requires accurate quantification of heating in deep organs without disrupting their physiology. This study, demonstrates that microwave-induced brain heating can be remotely monitored in vivo via luminescence thermometry using near-infrared luminescent silver sulfide (Ag2 S) nanoparticles. Their temperature-dependent luminescence lifetime is a reliable thermometric parameter for the measurement of absolute brain temperature. The in vivo results offer direct, real-time evidence of brain heating (up to 4 °C) under telecom exposure conditions (3 GHz). Moreover, they establish lifetime thermometry as a reliable, minimally invasive approach for investigating thermoregulation in deep tissues even under external electromagnetic stimulation