Chronic Low Back Pain and Incident Transient Ischemic Attack and Stroke in General Practices in Germany

The aim was to investigate the association between chronic low back pain (CLBP) and incident transient ischemic attack (TIA) and stroke in Germany. The present retrospective cohort study included adults aged >= 18 years who were diagnosed for the first time with CLBP in one of 1198 general practi...

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Autores: Jacob L, Smith L, Koyanagi A, Haro JM, Shin JI, Tanislav C, Schnitzler A, Kostev K
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p23539
Acceso en línea:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=23539
Access Level:acceso abierto
Palabra clave:chronic low back pain
transient ischemic attack
stroke
Germany
retrospective cohort study
epidemiology
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spelling Chronic Low Back Pain and Incident Transient Ischemic Attack and Stroke in General Practices in GermanyJacob LSmith LKoyanagi AHaro JMShin JITanislav CSchnitzler AKostev Kchronic low back paintransient ischemic attackstrokeGermanyretrospective cohort studyepidemiologyThe aim was to investigate the association between chronic low back pain (CLBP) and incident transient ischemic attack (TIA) and stroke in Germany. The present retrospective cohort study included adults aged >= 18 years who were diagnosed for the first time with CLBP in one of 1198 general practices in Germany in 2005-2019 (index date). Patients without CLBP were matched to those with CLBP (1:1) using a propensity score based on age, sex, the index year, the number of medical consultations per year during the follow-up, and the number of years of follow-up. In patients without CLBP, the index date was a randomly selected visit date. Both groups were followed for up to 10 years. There were 159,440 patients included in the study (mean (SD) age: 52.1 (16.5) years; 51.5% women). Within 10 years of the index date, 6.5% and 5.9% of patients with and without CLBP were diagnosed with TIA or stroke, respectively (log-rank p-value < 0.001). The Cox regression analysis corroborated these results, as there was a significant association between CLBP and incident TIA or stroke (HR = 1.28, 95% CI = 1.22-1.35). CLBP was positively and significantly associated with incident TIA and stroke in Germany. More research is warranted to better understand this relationship.MDPI2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=23539HealthcareISSN: 22279032reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p235392026-05-27T12:37:41Z
dc.title.none.fl_str_mv Chronic Low Back Pain and Incident Transient Ischemic Attack and Stroke in General Practices in Germany
title Chronic Low Back Pain and Incident Transient Ischemic Attack and Stroke in General Practices in Germany
spellingShingle Chronic Low Back Pain and Incident Transient Ischemic Attack and Stroke in General Practices in Germany
Jacob L
chronic low back pain
transient ischemic attack
stroke
Germany
retrospective cohort study
epidemiology
title_short Chronic Low Back Pain and Incident Transient Ischemic Attack and Stroke in General Practices in Germany
title_full Chronic Low Back Pain and Incident Transient Ischemic Attack and Stroke in General Practices in Germany
title_fullStr Chronic Low Back Pain and Incident Transient Ischemic Attack and Stroke in General Practices in Germany
title_full_unstemmed Chronic Low Back Pain and Incident Transient Ischemic Attack and Stroke in General Practices in Germany
title_sort Chronic Low Back Pain and Incident Transient Ischemic Attack and Stroke in General Practices in Germany
dc.creator.none.fl_str_mv Jacob L
Smith L
Koyanagi A
Haro JM
Shin JI
Tanislav C
Schnitzler A
Kostev K
author Jacob L
author_facet Jacob L
Smith L
Koyanagi A
Haro JM
Shin JI
Tanislav C
Schnitzler A
Kostev K
author_role author
author2 Smith L
Koyanagi A
Haro JM
Shin JI
Tanislav C
Schnitzler A
Kostev K
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv chronic low back pain
transient ischemic attack
stroke
Germany
retrospective cohort study
epidemiology
topic chronic low back pain
transient ischemic attack
stroke
Germany
retrospective cohort study
epidemiology
description The aim was to investigate the association between chronic low back pain (CLBP) and incident transient ischemic attack (TIA) and stroke in Germany. The present retrospective cohort study included adults aged >= 18 years who were diagnosed for the first time with CLBP in one of 1198 general practices in Germany in 2005-2019 (index date). Patients without CLBP were matched to those with CLBP (1:1) using a propensity score based on age, sex, the index year, the number of medical consultations per year during the follow-up, and the number of years of follow-up. In patients without CLBP, the index date was a randomly selected visit date. Both groups were followed for up to 10 years. There were 159,440 patients included in the study (mean (SD) age: 52.1 (16.5) years; 51.5% women). Within 10 years of the index date, 6.5% and 5.9% of patients with and without CLBP were diagnosed with TIA or stroke, respectively (log-rank p-value < 0.001). The Cox regression analysis corroborated these results, as there was a significant association between CLBP and incident TIA or stroke (HR = 1.28, 95% CI = 1.22-1.35). CLBP was positively and significantly associated with incident TIA and stroke in Germany. More research is warranted to better understand this relationship.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=23539
url https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=23539
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Healthcare
ISSN: 22279032
reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname:Fundació Sant Joan de Déu
instname_str Fundació Sant Joan de Déu
reponame_str r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
collection r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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