Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers

Multiple toothbrush designs have been developed to enhance dental biofilm removal and decrease bacterial contamination and retention over time. Therefore, the aim of this clinical study was to compare the efficacy of a prototype of a new double-sided thermoplastic polyurethane-based toothbrush with...

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Autores: Zúñiga Uhalde, Ignacio, Iniesta Albentosa, Margarita Isabel, Virto Ruiz, Leire, Ribeiro Vida, Honorato José, Alonso Español, Andrea, Hernández Ruiz de Azcárate, Fernando, Cardona Álvarez, John Jairo, Maher Lavandero, Anushiravan, Alonso Álvarez, Bettina María, Sanz Alonso, Mariano, Herrera González, David
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/73273
Acceso en línea:https://hdl.handle.net/20.500.14352/73273
Access Level:acceso abierto
Palabra clave:616.314-083
611.314
Dental biofilm
Toothbrush
Bacterial contamination
Plaque index
Anatomía
Odontología (Medicina)
2410.02 Anatomía Humana
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oai_identifier_str oai:docta.ucm.es:20.500.14352/73273
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spelling Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy VolunteersZúñiga Uhalde, IgnacioIniesta Albentosa, Margarita IsabelVirto Ruiz, LeireRibeiro Vida, Honorato JoséAlonso Español, AndreaHernández Ruiz de Azcárate, FernandoCardona Álvarez, John JairoMaher Lavandero, AnushiravanAlonso Álvarez, Bettina MaríaSanz Alonso, MarianoHerrera González, David616.314-083611.314Dental biofilmToothbrushBacterial contaminationPlaque indexAnatomíaOdontología (Medicina)2410.02 Anatomía HumanaMultiple toothbrush designs have been developed to enhance dental biofilm removal and decrease bacterial contamination and retention over time. Therefore, the aim of this clinical study was to compare the efficacy of a prototype of a new double-sided thermoplastic polyurethane-based toothbrush with that of a conventional nylon-bristle toothbrush. A crossover study was conducted in systemically healthy volunteers (n = 24) for two one-week periods plus one washout week. As outcome variables, plaque and gingival indices, total bacterial contamination of the toothbrushes by quantitative polymerase chain reaction (qPCR), and patient-reported outcomes were measured. Clinical and microbiological variables were analysed using a general linear model and Friedman and Wilcoxon signed-rank tests. No statistically significant differences between toothbrushes were detected neither for full-mouth PlI (p > 0.05) nor for GI (p > 0.05). Similarly, no statistically significant differences were detected for bacterial contamination after 40 seconds or 1 week of use, with results expressed either in CFU/mL or in CFU/mm2 (p > 0.05). In conclusion, the tested prototype toothbrush was as effective and safe as the control toothbrush, and the participating subjects did not experience any adverse effects from its use and rated its efficiency and effectiveness in cleaning their teeth as satisfactory.MDPIUniversidad Complutense de Madrid20222022-09-2220222022-09-22journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/73273reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/732732026-06-02T12:44:21Z
dc.title.none.fl_str_mv Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers
title Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers
spellingShingle Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers
Zúñiga Uhalde, Ignacio
616.314-083
611.314
Dental biofilm
Toothbrush
Bacterial contamination
Plaque index
Anatomía
Odontología (Medicina)
2410.02 Anatomía Humana
title_short Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers
title_full Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers
title_fullStr Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers
title_full_unstemmed Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers
title_sort Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers
dc.creator.none.fl_str_mv Zúñiga Uhalde, Ignacio
Iniesta Albentosa, Margarita Isabel
Virto Ruiz, Leire
Ribeiro Vida, Honorato José
Alonso Español, Andrea
Hernández Ruiz de Azcárate, Fernando
Cardona Álvarez, John Jairo
Maher Lavandero, Anushiravan
Alonso Álvarez, Bettina María
Sanz Alonso, Mariano
Herrera González, David
author Zúñiga Uhalde, Ignacio
author_facet Zúñiga Uhalde, Ignacio
Iniesta Albentosa, Margarita Isabel
Virto Ruiz, Leire
Ribeiro Vida, Honorato José
Alonso Español, Andrea
Hernández Ruiz de Azcárate, Fernando
Cardona Álvarez, John Jairo
Maher Lavandero, Anushiravan
Alonso Álvarez, Bettina María
Sanz Alonso, Mariano
Herrera González, David
author_role author
author2 Iniesta Albentosa, Margarita Isabel
Virto Ruiz, Leire
Ribeiro Vida, Honorato José
Alonso Español, Andrea
Hernández Ruiz de Azcárate, Fernando
Cardona Álvarez, John Jairo
Maher Lavandero, Anushiravan
Alonso Álvarez, Bettina María
Sanz Alonso, Mariano
Herrera González, David
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 616.314-083
611.314
Dental biofilm
Toothbrush
Bacterial contamination
Plaque index
Anatomía
Odontología (Medicina)
2410.02 Anatomía Humana
topic 616.314-083
611.314
Dental biofilm
Toothbrush
Bacterial contamination
Plaque index
Anatomía
Odontología (Medicina)
2410.02 Anatomía Humana
description Multiple toothbrush designs have been developed to enhance dental biofilm removal and decrease bacterial contamination and retention over time. Therefore, the aim of this clinical study was to compare the efficacy of a prototype of a new double-sided thermoplastic polyurethane-based toothbrush with that of a conventional nylon-bristle toothbrush. A crossover study was conducted in systemically healthy volunteers (n = 24) for two one-week periods plus one washout week. As outcome variables, plaque and gingival indices, total bacterial contamination of the toothbrushes by quantitative polymerase chain reaction (qPCR), and patient-reported outcomes were measured. Clinical and microbiological variables were analysed using a general linear model and Friedman and Wilcoxon signed-rank tests. No statistically significant differences between toothbrushes were detected neither for full-mouth PlI (p > 0.05) nor for GI (p > 0.05). Similarly, no statistically significant differences were detected for bacterial contamination after 40 seconds or 1 week of use, with results expressed either in CFU/mL or in CFU/mm2 (p > 0.05). In conclusion, the tested prototype toothbrush was as effective and safe as the control toothbrush, and the participating subjects did not experience any adverse effects from its use and rated its efficiency and effectiveness in cleaning their teeth as satisfactory.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-09-22
2022
2022-09-22
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/73273
url https://hdl.handle.net/20.500.14352/73273
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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