Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM

Detalles Bibliográficos
Autor: Ortiz Arduán, Alberto
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:dnet:biblosearchi::c3985209c0d22168bacf698b7d4c48a3
Acceso en línea:https://hdl.handle.net/10486/759540
https://dx.doi.org/10.1093/ndt/gfae240
Access Level:acceso abierto
Palabra clave:CAKUT
epidemiology
aetiology
genetic kidney disease
inherited kidney disease
kidney failure
kidney replacement therapy
Medicina
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spelling Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry studyOrtiz Arduán, AlbertoCAKUTepidemiologyaetiologygenetic kidney diseaseinherited kidney diseasekidney failurekidney replacement therapyMedicinaArtículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMBackground Inherited kidney diseases (IKDs) and congenital anomalies of the kidney and urinary tract (CAKUT) are causes of kidney failure requiring kidney replacement therapy (KRT) that major renal registries usually amalgamate into the primary renal disease(PRD) category ‘miscellaneous’ or in the glomerulonephritis or pyelonephritis categories. This makes IKDs invisible (except for polycystic kidney disease) and may negatively influence the use of genetic testing, which may identify a cause for IKDs and some CAKUT. Methods We re-examined the aetiology of KRT by composing a separate IKD and CAKUT PRD group using data from the European Renal Association (ERA) Registry. Results In 2019, IKD-CAKUT was the fourth most common cause of kidney failure among incident KRT patients, accounting for 8.9% of cases [IKD 7.4% (including 5.0% autosomal dominant polycystic kidney disease), CAKUT 1.5%], behind diabetes (23.0%), hypertension (14.4%) and glomerulonephritis (10.6%). IKD-CAKUT was the most common cause of kidney failure among patients <20 years of age (41.0% of cases), but their incidence rate was highest among those ages 45–74 years (22.5 per million age-related population). Among prevalent KRT patients, IKD-CAKUT (18.5%) and glomerulonephritis (18.7%) were the two most common causes of kidney failure overall, while IKD-CAKUT was the most common cause in women (21.6%) and in patients <45 years of age (29.1%). Conclusion IKD and CAKUT are common causes of kidney failure among KRT patients. Distinct categorization of IKD and CAKUT better characterizes the epidemiology of the causes of chronic kidney disease (CKD) and highlights the importance of genetic testing in the diagnostic workup of CKDA.O. and R.T. are supported by the Instituto de Salud Carlos III (ISCIII) RICORS program to RICORS2040 (RD21/0005/0001) and SPACKDc PMP21/00109, FEDER funds RD16/0009, PI22/00361 and Marato TV3 (Project 202036). K.J.J. reports research funding from the ERA and the European Society for Paediatric Nephrology. V.S.S. reports research funding from the ERAOxford University PressEuropean Renal Association (ERA)Departamento de MedicinaFacultad de MedicinaGobierno de EspañaInstituto de Salud Carlos III20242024-11-06research articlehttp://purl.org/coar/resource_type/c_2df8fbb1EVoRhttp://purl.org/coar/version/c_dc82b40f9837b551info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10486/759540https://dx.doi.org/10.1093/ndt/gfae24039508350reponame:Biblos-e Archivo. Repositorio Institucional de la UAMinstname:Universidad Autónoma de MadridInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:dnet:biblosearchi::c3985209c0d22168bacf698b7d4c48a32026-06-23T12:46:27Z
dc.title.none.fl_str_mv Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study
title Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study
spellingShingle Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study
Ortiz Arduán, Alberto
CAKUT
epidemiology
aetiology
genetic kidney disease
inherited kidney disease
kidney failure
kidney replacement therapy
Medicina
title_short Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study
title_full Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study
title_fullStr Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study
title_full_unstemmed Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study
title_sort Inherited kidney disease and CAKUT are common causes of kidney failure requiring kidney replacement therapy: an ERA Registry study
dc.creator.none.fl_str_mv Ortiz Arduán, Alberto
author Ortiz Arduán, Alberto
author_facet Ortiz Arduán, Alberto
author_role author
dc.contributor.none.fl_str_mv Departamento de Medicina
Facultad de Medicina
Gobierno de España
Instituto de Salud Carlos III
dc.subject.none.fl_str_mv CAKUT
epidemiology
aetiology
genetic kidney disease
inherited kidney disease
kidney failure
kidney replacement therapy
Medicina
topic CAKUT
epidemiology
aetiology
genetic kidney disease
inherited kidney disease
kidney failure
kidney replacement therapy
Medicina
description Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-11-06
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
EVoR
http://purl.org/coar/version/c_dc82b40f9837b551
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10486/759540
https://dx.doi.org/10.1093/ndt/gfae240
39508350
url https://hdl.handle.net/10486/759540
https://dx.doi.org/10.1093/ndt/gfae240
identifier_str_mv 39508350
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
European Renal Association (ERA)
publisher.none.fl_str_mv Oxford University Press
European Renal Association (ERA)
dc.source.none.fl_str_mv reponame:Biblos-e Archivo. Repositorio Institucional de la UAM
instname:Universidad Autónoma de Madrid
instname_str Universidad Autónoma de Madrid
reponame_str Biblos-e Archivo. Repositorio Institucional de la UAM
collection Biblos-e Archivo. Repositorio Institucional de la UAM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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