Optical coherence tomography angiography quantitative analysis and 10-year cardiovascular disease risk in the general population
PURPOSE:The aim of our study was to analyze the association between different cardiovascular risk scores and swept-source optical coherence tomography angiography (SS-OCTA) quantitative parameters in the general population. MATERIALS AND METHODS:We performed a retrospective study. This study enrolle...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) |
| Repositorio: | r-FISABIO. Repositorio Institucional de Producción Científica |
| OAI Identifier: | oai:fisabio.fundanetsuite.com:p19155 |
| Acceso en línea: | https://fisabio.portalinvestigacion.com/publicaciones/19155 |
| Access Level: | acceso abierto |
| Palabra clave: | Cardiovascular disease cardiovascular risk score coronary artery disease optical coherence tomography angiography vessel density |
| Sumario: | PURPOSE:The aim of our study was to analyze the association between different cardiovascular risk scores and swept-source optical coherence tomography angiography (SS-OCTA) quantitative parameters in the general population. MATERIALS AND METHODS:We performed a retrospective study. This study enrolled 111 eyes of 111 healthy patients. OCTA quantitative parameters (vessel density [VD] and foveal avascular zone area of superficial capillary plexus [SCP], deep capillary plexus [DCP], total capillary plexus, and choriocapillaris [CC]) of the OCTA cube of 4.5 mm x 4.5 mm were recorded. RESULTS:A decrease of parafoveal and total VD in TCP was demonstrated in patients with higher cardiovascular risk (P < 0.05). Conversely, no differences were demonstrated in VD at SCP, DCP, and CC (P > 0.05). Correlation analysis showed a significant, although poor, negative correlation between parafoveal and total VD at SCP and TCP and 10-year cardiovascular disease (CVD) risk (P < 0.05 and r < 0.500). CONCLUSIONS:When normative data are available, OCTA quantitative analysis might be used as a main tool for the primary prevention of CVD. Nevertheless, further prospective studies are needed to confirm this hypothesis. |
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