ctDNA transiting into urine is ultrashort and facilitates noninvasive liquid biopsy of HPV+ oropharyngeal cancer

[Backgound] Transrenal cell-free tumor DNA (TR-ctDNA), which transits from the bloodstream into urine, has the potential to enable noninvasive cancer detection for a wide variety of nonurologic cancer types.

Detalles Bibliográficos
Autores: Bhambhani, Chandan, Kang, Qing, Hovelson, Daniel H., Sandford, Erin, Olesnavich, Mary, Dermody, Sarah M., Wolfgang, Jenny, Tuck, Kirsten L., Brummel, Collin, Bhangale, Apurva D., He, Kuang, Gutierrez, Marc G., Lindstrom, Ryan H., Liu, Chia-Jen, Tuck, Melissa, Kandarpa, Malathi, Mierzwa, Michelle, Casper, Keith, Prince, Mark E., Krauss, John C., Talpaz, Moshe, Henry, N Lynn, Giráldez, María D., Ramnath, Nithya, Tomlins, Scott A., Swiecicki, Paul L., Brenner, J. Chad, Tewari, Muneesh
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/371065
Acceso en línea:http://hdl.handle.net/10261/371065
https://api.elsevier.com/content/abstract/scopus_id/85188589116
Access Level:acceso abierto
Palabra clave:Oncology
Cancer
Diagnostics
Head and neck cancer
Descripción
Sumario:[Backgound] Transrenal cell-free tumor DNA (TR-ctDNA), which transits from the bloodstream into urine, has the potential to enable noninvasive cancer detection for a wide variety of nonurologic cancer types.