Malignant pleural effusion: from bench to bedside

Malignant pleural effusion (MPE) is a common but serious condition that is related with poor quality of life, morbidity and mortality. Its incidence and associated healthcare costs are rising and its management remains palliative, with median survival ranging from 3 to 12 months. During the last dec...

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Bibliographic Details
Authors: Psallidas, Ioannis, Kalomenidis, Ioannis, Porcel Pérez, José Manuel, Robinson, Bruce W., Stathopoulos, Georgios T.
Format: article
Status:Published version
Publication Date:2016
Country:España
Institution:Universitat de Lleida (UdL)
Repository:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/57243
Online Access:https://doi.org/10.1002/cyto.9901404110.1183/16000617.0019-2016
http://hdl.handle.net/10459.1/57243
Access Level:Open access
Description
Summary:Malignant pleural effusion (MPE) is a common but serious condition that is related with poor quality of life, morbidity and mortality. Its incidence and associated healthcare costs are rising and its management remains palliative, with median survival ranging from 3 to 12 months. During the last decade there has been significant progress in unravelling the pathophysiology of MPE, as well as its diagnostics, imaging, and management. Nowadays, formerly bed-ridden patients are genotyped, phenotyped, and treated on an ambulatory basis. This article attempts to provide a comprehensive overview of current advances in MPE from bench to bedside. In addition, it highlights unanswered questions in current clinical practice and suggests future directions for basic and clinical research in the field.