Concordance between two models of stratification for patients living with HIV infection to providing pharmaceutical care

Objective To determine the degree of agreement of two differents stratification models for pharmaceutical care to people living with HIV. Methods This was a single-centre observational prospective cohort study of patients with regular follow-up in pharmaceutical care consultations according to the C...

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Autores: Morillo Verdugo, Ramón Alejandro, Parra Zuñiga, Sebastián, Álvarez de Sotomayor Paz, María, Contreras Macías, Enrique, Robustillo Cortes, María de las Aguas
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2024
País:España
Recursos:Universidad de Sevilla (US)
Repositório:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/168239
Acesso em linha:https://hdl.handle.net/11441/168239
https://doi.org/10.1016/j.farma.2024.01.009
https://doi.org/10.1016/j.farma.2024.05.007
Access Level:Acceso aberto
Palavra-chave:Stratification
Pharmaceutical care
HIV/AIDS
Outcome assessment
Estratificación
Atención farmacéutica
VIH/SIDA
Resultados en salud
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oai_identifier_str oai:idus.us.es:11441/168239
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Concordance between two models of stratification for patients living with HIV infection to providing pharmaceutical care
Concordancia entre 2 modelos de estratificación de pacientes que viven con el VIH para la prestación de atención farmacéutica
title Concordance between two models of stratification for patients living with HIV infection to providing pharmaceutical care
spellingShingle Concordance between two models of stratification for patients living with HIV infection to providing pharmaceutical care
Morillo Verdugo, Ramón Alejandro
Stratification
Pharmaceutical care
HIV/AIDS
Outcome assessment
Estratificación
Atención farmacéutica
VIH/SIDA
Resultados en salud
title_short Concordance between two models of stratification for patients living with HIV infection to providing pharmaceutical care
title_full Concordance between two models of stratification for patients living with HIV infection to providing pharmaceutical care
title_fullStr Concordance between two models of stratification for patients living with HIV infection to providing pharmaceutical care
title_full_unstemmed Concordance between two models of stratification for patients living with HIV infection to providing pharmaceutical care
title_sort Concordance between two models of stratification for patients living with HIV infection to providing pharmaceutical care
dc.creator.none.fl_str_mv Morillo Verdugo, Ramón Alejandro
Parra Zuñiga, Sebastián
Álvarez de Sotomayor Paz, María
Contreras Macías, Enrique
Robustillo Cortes, María de las Aguas
Parra Zuñiga, Sebastián
author Morillo Verdugo, Ramón Alejandro
author_facet Morillo Verdugo, Ramón Alejandro
Parra Zuñiga, Sebastián
Álvarez de Sotomayor Paz, María
Contreras Macías, Enrique
Robustillo Cortes, María de las Aguas
author_role author
author2 Parra Zuñiga, Sebastián
Álvarez de Sotomayor Paz, María
Contreras Macías, Enrique
Robustillo Cortes, María de las Aguas
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Farmacología
dc.subject.none.fl_str_mv Stratification
Pharmaceutical care
HIV/AIDS
Outcome assessment
Estratificación
Atención farmacéutica
VIH/SIDA
Resultados en salud
topic Stratification
Pharmaceutical care
HIV/AIDS
Outcome assessment
Estratificación
Atención farmacéutica
VIH/SIDA
Resultados en salud
description Objective To determine the degree of agreement of two differents stratification models for pharmaceutical care to people living with HIV. Methods This was a single-centre observational prospective cohort study of patients with regular follow-up in pharmaceutical care consultations according to the Capacity-Motivation-Opportunity methodology, conducted between January 1st and March 31th, 2023. Patients received the pharmacotherapeutic interventions applied routinely to ambulatory care patients according to this model. As part of the usual clinical practice, the presence or absence of the variables that apply to both stratification models were collected. The scores obtained and the corresponding stratification level were collected for each patient according to both stratification models published (ST-2017 and ST-2022). To analyze the reliability between the measurements of two numerical score models of the stratification level with both tools, their degree of concordance was calculated using the intraclass correlation coefficient. Likewise, reliability was also evaluated from a qualitative perspective by means of Cohen's Kappa coefficient. Additionally, the existence of correlation between the scores of the two models was assessed by calculating Pearson's correlation coefficient. Results Of the total of 758 patients being followed in the cohort, finally, 233 patients were enrolled. The distribution of patients for each stratification model was: ST-2017: 59.7% level-3, 25.3% level-2 and 15.0% level-1, while for ST-2022: 60.9% level-3, 26.6% level-2 and 12.4% level-1. It was observed that the reclassification was symmetrical (p = 0.317). The qualitative analysis of the agreement between the models showed a good Cohen's kappa value, (K = 0.66). A value of 0.563 was found as the intraclass correlation coefficient. Finally, the correlation analysis between the quantitative scores of the two models yielded a Pearson correlation coefficient of 0.86. Conclusions The concordance between the two models was good, which confirms that the multidimensional adaptation and simplification of the model were correct and that its use can be extended in routine clinical practice.
publishDate 2024
dc.date.none.fl_str_mv 2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/168239
https://doi.org/10.1016/j.farma.2024.01.009
https://doi.org/10.1016/j.farma.2024.05.007
url https://hdl.handle.net/11441/168239
https://doi.org/10.1016/j.farma.2024.01.009
https://doi.org/10.1016/j.farma.2024.05.007
dc.language.none.fl_str_mv Español
language_invalid_str_mv Español
dc.relation.none.fl_str_mv Farmacia Hospitalaria, 48 (5), 212-221.
https://doi.org/10.1016/j.farma.2024.01.009
https://doi.org/10.1016/j.farma.2024.05.007
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
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spelling Concordance between two models of stratification for patients living with HIV infection to providing pharmaceutical careConcordancia entre 2 modelos de estratificación de pacientes que viven con el VIH para la prestación de atención farmacéuticaMorillo Verdugo, Ramón AlejandroParra Zuñiga, SebastiánÁlvarez de Sotomayor Paz, MaríaContreras Macías, EnriqueRobustillo Cortes, María de las AguasParra Zuñiga, SebastiánStratificationPharmaceutical careHIV/AIDSOutcome assessmentEstratificaciónAtención farmacéuticaVIH/SIDAResultados en saludObjective To determine the degree of agreement of two differents stratification models for pharmaceutical care to people living with HIV. Methods This was a single-centre observational prospective cohort study of patients with regular follow-up in pharmaceutical care consultations according to the Capacity-Motivation-Opportunity methodology, conducted between January 1st and March 31th, 2023. Patients received the pharmacotherapeutic interventions applied routinely to ambulatory care patients according to this model. As part of the usual clinical practice, the presence or absence of the variables that apply to both stratification models were collected. The scores obtained and the corresponding stratification level were collected for each patient according to both stratification models published (ST-2017 and ST-2022). To analyze the reliability between the measurements of two numerical score models of the stratification level with both tools, their degree of concordance was calculated using the intraclass correlation coefficient. Likewise, reliability was also evaluated from a qualitative perspective by means of Cohen's Kappa coefficient. Additionally, the existence of correlation between the scores of the two models was assessed by calculating Pearson's correlation coefficient. Results Of the total of 758 patients being followed in the cohort, finally, 233 patients were enrolled. The distribution of patients for each stratification model was: ST-2017: 59.7% level-3, 25.3% level-2 and 15.0% level-1, while for ST-2022: 60.9% level-3, 26.6% level-2 and 12.4% level-1. It was observed that the reclassification was symmetrical (p = 0.317). The qualitative analysis of the agreement between the models showed a good Cohen's kappa value, (K = 0.66). A value of 0.563 was found as the intraclass correlation coefficient. Finally, the correlation analysis between the quantitative scores of the two models yielded a Pearson correlation coefficient of 0.86. Conclusions The concordance between the two models was good, which confirms that the multidimensional adaptation and simplification of the model were correct and that its use can be extended in routine clinical practice.Objetivo determinar el grado de concordancia de 2 modelos diferentes de estratificación de la atención farmacéutica a personas que viven con el VIH. Método se trata de un estudio de cohortes prospectivo observacional unicéntrico de pacientes con seguimiento regular en consultas de atención farmacéutica según la metodología Capacidad-Motivación-Oportunidad, realizado entre el 1 de enero y el 31 de marzo de 2023. Los pacientes recibieron las intervenciones farmacoterapéuticas aplicadas de forma rutinaria a los pacientes de atención ambulatoria según este modelo. Como parte de la práctica clínica habitual, se recogió la presencia o ausencia de las variables que se aplican a ambos modelos de estratificación. Para cada paciente se recogieron las puntuaciones obtenidas y el nivel de estratificación correspondiente según ambos modelos de estratificación publicados (ST-2017 y ST-2022). Para analizar la fiabilidad entre las mediciones de 2 modelos de puntuación numérica del nivel de estratificación con ambas herramientas, se calculó su grado de concordancia mediante el coeficiente de correlación intraclase. Asimismo, también se evaluó la fiabilidad desde una perspectiva cualitativa mediante el coeficiente Kappa de Cohen. Adicionalmente, se evaluó la existencia de correlación entre las puntuaciones de ambos modelos mediante el cálculo del coeficiente de correlación de Pearson. Resultados del total de 758 pacientes en seguimiento de la cohorte, finalmente se incluyeron 233 pacientes. La distribución de pacientes para cada modelo de estratificación fue: ST-2017: 59,7% nivel 3; 25,3% nivel 2 y 15,0% nivel 1; mientras que para ST-2022: 60,9% nivel 3; 26,6% nivel 2 y 12,4% nivel 1. Se observó que la reclasificación era simétrica (p = 0,317). En el análisis cualitativo de la concordancia entre los modelos se mostró un buen valor kappa de Cohen (K = 0,66). Se halló un valor de 0,563 como coeficiente de correlación intraclase. Por último, el análisis de correlación entre las puntuaciones cuantitativas de los 2 modelos arrojó un coeficiente de correlación de Pearson de 0,86. Conclusiones la concordancia entre los 2 modelos fue buena, lo que confirma que la adaptación multidimensional y la simplificación del modelo fueron correctas y que su uso puede extenderse en la práctica clínica habitual.ElsevierFarmacología2024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/168239https://doi.org/10.1016/j.farma.2024.01.009https://doi.org/10.1016/j.farma.2024.05.007reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)EspañolFarmacia Hospitalaria, 48 (5), 212-221.https://doi.org/10.1016/j.farma.2024.01.009https://doi.org/10.1016/j.farma.2024.05.007info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1682392026-06-17T12:51:07Z
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