Site-Selective functionalization of C(sp3 ) Vicinal Boronic Esters
Selective functionalization of the C−B bond in 1,2- bis(boronate) esters has emerged as a powerful tool to prepare 1,2- difunctionalized compounds with stereocontrol. Selective Suzuki crosscoupling, oxidation, amination, and homologation reactions serve as platforms to prepare a wide variety of comp...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2022 |
| País: | España |
| Institución: | Universidad Autónoma de Madrid |
| Repositorio: | Biblos-e Archivo. Repositorio Institucional de la UAM |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.uam.es:10486/705965 |
| Acceso en línea: | http://hdl.handle.net/10486/705965 https://dx.doi.org/10.1021/acscatal.2c02857 |
| Access Level: | acceso abierto |
| Palabra clave: | 1,2-shift Boro-Wittig reaction Boron Boronate allylation Site-selective functionalization Suzuki-Miyaura cross-coupling Vicinal boronates Química |
| Sumario: | Selective functionalization of the C−B bond in 1,2- bis(boronate) esters has emerged as a powerful tool to prepare 1,2- difunctionalized compounds with stereocontrol. Selective Suzuki crosscoupling, oxidation, amination, and homologation reactions serve as platforms to prepare a wide variety of compounds from a common intermediate. The exquisite selectivity offered and their easy preparation from feedstock material using a myriad of catalytic transformations make them attractive building blocks for the preparation of complex molecules. In this Perspective, we summarize the examples of selective C−B bond functionalization of vicinal bis(boronates), attending to the nature of the C−B bond functionalization |
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