Meningococcal disease in the Middle East: A report from the Global Meningococcal Initiative.

This review details recent findings from the Global Meningococcal Initiative's (GMI) recent meeting on the surveillance and control strategies for invasive meningococcal disease in the Middle East. The nature of case reporting and notification varies across the region, with many countries using...

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Detalles Bibliográficos
Autores: Al-Abri, Seif S, Abuhasan, Musallam Yunus, Albayat, Soha Shawqi A, Bai, Xilian, Bastaki, Hamad, Borrow, Ray, Caugant, Dominique A, Dbaibo, Ghassan, Deghmane, Ala-Eddine, Dinleyici, Ener Cagri, Ghuneim, Nedal, Sheek-Hussein, Mohamud, Lucidarme, Jay, Leng, Sean, Koliou, Maria G, Sáfadi, Marco A P, Salman, Jameela Al, Al-Sanouri, Tarek, Smith, Vinny, Taha, Muhamed-Kheir, Vazquez-Moreno, Julio Alberto, Wright, Claire, Yezli, Saber
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/26415
Acceso en línea:https://hdl.handle.net/20.500.12105/26415
Access Level:acceso abierto
Palabra clave:Meningococcal disease
Middle East
Serogroup
Surveillance
Vaccination
Disease Outbreaks
Humans
Incidence
Meningococcal Infections
Meningococcal Vaccines
Neisseria meningitidis
Descripción
Sumario:This review details recent findings from the Global Meningococcal Initiative's (GMI) recent meeting on the surveillance and control strategies for invasive meningococcal disease in the Middle East. The nature of case reporting and notification varies across the region, with many countries using bacterial meningitis as an IMD case definition in lieu of meningitis and septicaemia. This may overlook a significant burden associated with IMD leading to underreporting or misreporting of the disease. Based on these current definitions, IMD reported incidence remains low across the region, with historical outbreaks mainly occurring due to the Hajj and Umrah mass gatherings. The use of case confirmation techniques also varies in Middle Eastern countries. While typical microbiological techniques, such as culture and Gram staining, are widely used for characterisation, polymerase chain reaction (PCR) testing is utilised in a small number of countries. PCR testing may be inaccessible for several reasons including sample transportation, cost, or a lack of laboratory expertise. These barriers, not exclusive to PCR use, may impact surveillance systems more broadly. Another concern throughout the region is potentially widespread ciprofloxacin resistance since its use for chemoprophylaxis remains high in many countries.

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