Identification of resilient sows in porcine reproductive and respiratory syndrome virus-infected farms

The identification of resilient sows can improve reproductive performance in farms exposed to multiple challenges. A common challenge is the porcine reproductive and respiratory syndrome virus (PRRSV). A key issue to deal with disease resilience is to set up a feasible phenotyping strategy. Our aim...

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Detalles Bibliográficos
Autores: Abella Falcó, Glòria, Novell, Elena, Tarancón, Vicens, Varona Aguado, Luís, Pena i Subirà, Ramona Natacha, Estany Illa, Joan, Fraile Sauce, Lorenzo José
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Universitat de Lleida (UdL)
Repositorio:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/66660
Acceso en línea:https://doi.org/10.1093/jas/skz192
http://hdl.handle.net/10459.1/66660
Access Level:acceso abierto
Palabra clave:PRRSV
Resilience
Phenotyping method
Truges
Malalties infeccioses en els animals
Sows
Communicable diseases in animals
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spelling Identification of resilient sows in porcine reproductive and respiratory syndrome virus-infected farmsAbella Falcó, GlòriaNovell, ElenaTarancón, VicensVarona Aguado, LuísPena i Subirà, Ramona NatachaEstany Illa, JoanFraile Sauce, Lorenzo JoséPRRSVResiliencePhenotyping methodTrugesMalalties infeccioses en els animalsSowsCommunicable diseases in animalsThe identification of resilient sows can improve reproductive performance in farms exposed to multiple challenges. A common challenge is the porcine reproductive and respiratory syndrome virus (PRRSV). A key issue to deal with disease resilience is to set up a feasible phenotyping strategy. Our aim was to develop a phenotyping criterion to discriminate susceptible from resilient sows in PRRSV-infected farms. A total of 517 Landrace x Large White gilts were classified as resilient (R) or susceptible (S) to PRRSV virus, following vaccination with MLV-PRRSV at 6-7 wk of age, in a PRRSV negative multiplication farm. Female piglets were phenotyped as R if their serum was negative to PRRSV at 7 and 21 d post-vaccination (DPV) or as S if their serum was positive at 7 and/or 21 DPV. Amongst them, 382 gilts were transferred to a PRRSV-positive production farm, where the number of piglets born alive (NBA), stillborn (NSB), mummified (NMU), lost (NLP=NSB+NMU) and total born (NTB = NBA+NLP) were recorded for almost three years. Data were collected during two periods according to the PRRSV farm health status, which were confirmed as either PRRSV-positive stable (endemic) or inestable (epidemic). Analyses were carried out under a Bayesian approach. The heritability for the resilience criterion was estimated using a threshold model. A linear (for NTB and NBA) and a binomial model (for NSB, NMU and NLP) on the resilience criterion by the farm health status were used to assess the difference between R and S sows. The heritability of the resilience criterion was 0.46 (SD 0.06). The probability of a piglet being lost was greater (≥0.97) in S than in R litters, regardless of whether the delivery occurred during a PRRSV outbreak (20.5% vs 17.0%) or not (15.8% vs 13.7%). The lower piglet mortality rate in R sows was due to NSB, in the endemic phase (13.0% vs 15.0% of NTB, with a posterior probability of 98% of S sows showing higher NSB than R sows), and to NMU, in the epidemic phase (4.0% vs 8.4% of NTB, with a posterior probability of >99% of S sows showing higher NMU than R sows). During a PRRSV outbreak, the S sows were twice as likely to give birth to a mummified piglet as compared to R sows. These findings provide evidence that the described phenotyping scheme has a potential use as a PRRSV resilience criterion.This research was funded by FEDER project (COMRDI16-1-0035-03). Glòria Abella is a recipient of an industrial PhD award from the Government of Catalonia, Spain (No. 2013 DI 027)American Society of Animal Science2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfhttps://doi.org/10.1093/jas/skz192http://hdl.handle.net/10459.1/66660reponame:Repositori Obert UdL instname:Universitat de Lleida (UdL)InglésVersió postprint del document publicat a: https://doi.org/10.1093/jas/skz192Journal of Animal Science, 2019, vol. 97, num. 8, p. 3228-3236(c) Abella Falcó, Glòria et al., 2019info:eu-repo/semantics/openAccessoai:repositori.udl.cat:10459.1/666602026-06-24T12:42:17Z
dc.title.none.fl_str_mv Identification of resilient sows in porcine reproductive and respiratory syndrome virus-infected farms
title Identification of resilient sows in porcine reproductive and respiratory syndrome virus-infected farms
spellingShingle Identification of resilient sows in porcine reproductive and respiratory syndrome virus-infected farms
Abella Falcó, Glòria
PRRSV
Resilience
Phenotyping method
Truges
Malalties infeccioses en els animals
Sows
Communicable diseases in animals
title_short Identification of resilient sows in porcine reproductive and respiratory syndrome virus-infected farms
title_full Identification of resilient sows in porcine reproductive and respiratory syndrome virus-infected farms
title_fullStr Identification of resilient sows in porcine reproductive and respiratory syndrome virus-infected farms
title_full_unstemmed Identification of resilient sows in porcine reproductive and respiratory syndrome virus-infected farms
title_sort Identification of resilient sows in porcine reproductive and respiratory syndrome virus-infected farms
dc.creator.none.fl_str_mv Abella Falcó, Glòria
Novell, Elena
Tarancón, Vicens
Varona Aguado, Luís
Pena i Subirà, Ramona Natacha
Estany Illa, Joan
Fraile Sauce, Lorenzo José
author Abella Falcó, Glòria
author_facet Abella Falcó, Glòria
Novell, Elena
Tarancón, Vicens
Varona Aguado, Luís
Pena i Subirà, Ramona Natacha
Estany Illa, Joan
Fraile Sauce, Lorenzo José
author_role author
author2 Novell, Elena
Tarancón, Vicens
Varona Aguado, Luís
Pena i Subirà, Ramona Natacha
Estany Illa, Joan
Fraile Sauce, Lorenzo José
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv PRRSV
Resilience
Phenotyping method
Truges
Malalties infeccioses en els animals
Sows
Communicable diseases in animals
topic PRRSV
Resilience
Phenotyping method
Truges
Malalties infeccioses en els animals
Sows
Communicable diseases in animals
description The identification of resilient sows can improve reproductive performance in farms exposed to multiple challenges. A common challenge is the porcine reproductive and respiratory syndrome virus (PRRSV). A key issue to deal with disease resilience is to set up a feasible phenotyping strategy. Our aim was to develop a phenotyping criterion to discriminate susceptible from resilient sows in PRRSV-infected farms. A total of 517 Landrace x Large White gilts were classified as resilient (R) or susceptible (S) to PRRSV virus, following vaccination with MLV-PRRSV at 6-7 wk of age, in a PRRSV negative multiplication farm. Female piglets were phenotyped as R if their serum was negative to PRRSV at 7 and 21 d post-vaccination (DPV) or as S if their serum was positive at 7 and/or 21 DPV. Amongst them, 382 gilts were transferred to a PRRSV-positive production farm, where the number of piglets born alive (NBA), stillborn (NSB), mummified (NMU), lost (NLP=NSB+NMU) and total born (NTB = NBA+NLP) were recorded for almost three years. Data were collected during two periods according to the PRRSV farm health status, which were confirmed as either PRRSV-positive stable (endemic) or inestable (epidemic). Analyses were carried out under a Bayesian approach. The heritability for the resilience criterion was estimated using a threshold model. A linear (for NTB and NBA) and a binomial model (for NSB, NMU and NLP) on the resilience criterion by the farm health status were used to assess the difference between R and S sows. The heritability of the resilience criterion was 0.46 (SD 0.06). The probability of a piglet being lost was greater (≥0.97) in S than in R litters, regardless of whether the delivery occurred during a PRRSV outbreak (20.5% vs 17.0%) or not (15.8% vs 13.7%). The lower piglet mortality rate in R sows was due to NSB, in the endemic phase (13.0% vs 15.0% of NTB, with a posterior probability of 98% of S sows showing higher NSB than R sows), and to NMU, in the epidemic phase (4.0% vs 8.4% of NTB, with a posterior probability of >99% of S sows showing higher NMU than R sows). During a PRRSV outbreak, the S sows were twice as likely to give birth to a mummified piglet as compared to R sows. These findings provide evidence that the described phenotyping scheme has a potential use as a PRRSV resilience criterion.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1093/jas/skz192
http://hdl.handle.net/10459.1/66660
url https://doi.org/10.1093/jas/skz192
http://hdl.handle.net/10459.1/66660
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1093/jas/skz192
Journal of Animal Science, 2019, vol. 97, num. 8, p. 3228-3236
dc.rights.none.fl_str_mv (c) Abella Falcó, Glòria et al., 2019
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Abella Falcó, Glòria et al., 2019
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv American Society of Animal Science
publisher.none.fl_str_mv American Society of Animal Science
dc.source.none.fl_str_mv reponame:Repositori Obert UdL
instname:Universitat de Lleida (UdL)
instname_str Universitat de Lleida (UdL)
reponame_str Repositori Obert UdL
collection Repositori Obert UdL
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812455

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