Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars

In the past decade, astrochemistry has witnessed an impressive increase in the number of detections of complex organic molecules. Some of these species are of prebiotic interest such as glycolaldehyde, the simplest sugar, or aminoacetonitrile, a possible precursor of glycine. Recently, we have repor...

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Autores: Jimenez-Serra, Izaskun, Martín Pintado, J., Rivilla, Victor M., Rodríguez Almeida, L. F., Alonso Alonso, E. R., Zeng, Shaoshan, Cocinero, E. J., Martín, S., Requena Torres, Miguel Angel, Martín Doménech, R., Testi, L.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Instituto Nacional de Técnica Aeroespacial (INTA)
Repositorio:DIGITAL.INTA Repositorio Digital del Instituto Nacional de Técnica Aeroespacial
OAI Identifier:oai:digital.inta.es:20.500.12666/270
Acceso en línea:https://www.liebertpub.com/doi/10.1089/ast.2019.2125
http://hdl.handle.net/20.500.12666/270
Access Level:acceso abierto
Palabra clave:Astrochemistry
Radioastronomy
Molecules
Prebiotic chemistry
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dc.title.none.fl_str_mv Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars
title Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars
spellingShingle Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars
Jimenez-Serra, Izaskun
Astrochemistry
Radioastronomy
Molecules
Prebiotic chemistry
title_short Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars
title_full Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars
title_fullStr Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars
title_full_unstemmed Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars
title_sort Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars
dc.creator.none.fl_str_mv Jimenez-Serra, Izaskun
Martín Pintado, J.
Rivilla, Victor M.
Rodríguez Almeida, L. F.
Alonso Alonso, E. R.
Zeng, Shaoshan
Cocinero, E. J.
Martín, S.
Requena Torres, Miguel Angel
Martín Doménech, R.
Testi, L.
author Jimenez-Serra, Izaskun
author_facet Jimenez-Serra, Izaskun
Martín Pintado, J.
Rivilla, Victor M.
Rodríguez Almeida, L. F.
Alonso Alonso, E. R.
Zeng, Shaoshan
Cocinero, E. J.
Martín, S.
Requena Torres, Miguel Angel
Martín Doménech, R.
Testi, L.
author_role author
author2 Martín Pintado, J.
Rivilla, Victor M.
Rodríguez Almeida, L. F.
Alonso Alonso, E. R.
Zeng, Shaoshan
Cocinero, E. J.
Martín, S.
Requena Torres, Miguel Angel
Martín Doménech, R.
Testi, L.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Unidad de Excelencia Científica María de Maeztu Centro de Astrobiología del Instituto Nacional de Técnica Aeroespacial y CSIC, MDM-2017-0737
Cocinero, E. J. [0000-0001-7632-3728]
Martín Doménech, R. [0000-0001-6496-9791]
Gobierno Vasco
Agencia Estatal de Investigación (AEI)
Ministerio de Economía y Competitividad (MINECO)
dc.subject.none.fl_str_mv Astrochemistry
Radioastronomy
Molecules
Prebiotic chemistry
topic Astrochemistry
Radioastronomy
Molecules
Prebiotic chemistry
description In the past decade, astrochemistry has witnessed an impressive increase in the number of detections of complex organic molecules. Some of these species are of prebiotic interest such as glycolaldehyde, the simplest sugar, or aminoacetonitrile, a possible precursor of glycine. Recently, we have reported the detection of two new nitrogen-bearing complex organics, glycolonitrile and Z-cyanomethanimine, known to be intermediate species in the formation process of ribonucleotides within theories of a primordial RNA-world for the origin of life. In this study, we present deep and high-sensitivity observations toward two of the most chemically rich sources in the galaxy: a giant molecular cloud in the center of the Milky Way (G + 0.693-0.027) and a proto-Sun (IRAS16293-2422 B). Our aim is to explore whether the key precursors considered to drive the primordial RNA-world chemistry are also found in space. Our high-sensitivity observations reveal that urea is present in G + 0.693-0.027 with an abundance of similar to 5 x 10(-11). This is the first detection of this prebiotic species outside a star-forming region. Urea remains undetected toward the proto-Sun IRAS16293-2422 B (upper limit to its abundance of <= 2 x 10(-11)). Other precursors of the RNA-world chemical scheme such as glycolaldehyde or cyanamide are abundant in space, but key prebiotic species such as 2-amino-oxazole, glyceraldehyde, or dihydroxyacetone are not detected in either source. Future more sensitive observations targeting the brightest transitions of these species will be needed to disentangle whether these large prebiotic organics are certainly present in space.
publishDate 2020
dc.date.none.fl_str_mv 2020
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://www.liebertpub.com/doi/10.1089/ast.2019.2125
http://hdl.handle.net/20.500.12666/270
url https://www.liebertpub.com/doi/10.1089/ast.2019.2125
http://hdl.handle.net/20.500.12666/270
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv CONTRIBUCION ESPAÑOLA A LAS MISIONES ESPACIALES CRIOGENICAS SPICA Y ATHENA, POST-OPERACIONES DE HERSCHEL Y EXPLOTACION CIENTIFICA MULTIFRECUENCIA
info:eu-repo/grantAgreement/MINECO//ESP2015-65597-C4-1-R
METODOS ESTRUCTURALES DE DISEÑO DE GLICOPEPTIDOS PARA VACUNAS ANTICANCERIGENAS
CONTRIBUCION ESPAÑOLA EN CRIOGENIA A MISIONES ESPACIALES: DESARROLLOS PARA SPICA Y ATHENA, POST-OPERACIONES DE HERSCHEL Y EXPLOTACION CIENTIFICA MULTIFRECUENCIA
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2017-89150-R
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/ESP2017-86582-C4-1-R
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
Copyright 2020, Mary Ann Liebert, Inc., publishers
https://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
Copyright 2020, Mary Ann Liebert, Inc., publishers
https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Mary Ann Liebert Publishers
publisher.none.fl_str_mv Mary Ann Liebert Publishers
dc.source.none.fl_str_mv reponame:DIGITAL.INTA Repositorio Digital del Instituto Nacional de Técnica Aeroespacial
instname:Instituto Nacional de Técnica Aeroespacial (INTA)
instname_str Instituto Nacional de Técnica Aeroespacial (INTA)
reponame_str DIGITAL.INTA Repositorio Digital del Instituto Nacional de Técnica Aeroespacial
collection DIGITAL.INTA Repositorio Digital del Instituto Nacional de Técnica Aeroespacial
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spelling Toward the RNA-World in the Interstellar Medium—Detection of Urea and Search of 2-Amino-oxazole and Simple SugarsJimenez-Serra, IzaskunMartín Pintado, J.Rivilla, Victor M.Rodríguez Almeida, L. F.Alonso Alonso, E. R.Zeng, ShaoshanCocinero, E. J.Martín, S.Requena Torres, Miguel AngelMartín Doménech, R.Testi, L.AstrochemistryRadioastronomyMoleculesPrebiotic chemistryIn the past decade, astrochemistry has witnessed an impressive increase in the number of detections of complex organic molecules. Some of these species are of prebiotic interest such as glycolaldehyde, the simplest sugar, or aminoacetonitrile, a possible precursor of glycine. Recently, we have reported the detection of two new nitrogen-bearing complex organics, glycolonitrile and Z-cyanomethanimine, known to be intermediate species in the formation process of ribonucleotides within theories of a primordial RNA-world for the origin of life. In this study, we present deep and high-sensitivity observations toward two of the most chemically rich sources in the galaxy: a giant molecular cloud in the center of the Milky Way (G + 0.693-0.027) and a proto-Sun (IRAS16293-2422 B). Our aim is to explore whether the key precursors considered to drive the primordial RNA-world chemistry are also found in space. Our high-sensitivity observations reveal that urea is present in G + 0.693-0.027 with an abundance of similar to 5 x 10(-11). This is the first detection of this prebiotic species outside a star-forming region. Urea remains undetected toward the proto-Sun IRAS16293-2422 B (upper limit to its abundance of <= 2 x 10(-11)). Other precursors of the RNA-world chemical scheme such as glycolaldehyde or cyanamide are abundant in space, but key prebiotic species such as 2-amino-oxazole, glyceraldehyde, or dihydroxyacetone are not detected in either source. Future more sensitive observations targeting the brightest transitions of these species will be needed to disentangle whether these large prebiotic organics are certainly present in space.We thank Carlos Briones for illuminating discussions about the primordial RNA-world hypothesis for the origin of life. We also acknowledge the Basque Government (PIBA 2018-11), the UPV/EHU (PPG17/10), and Fundacion BBVA for financial support. Computational and laser facilities of the UPV/EHU were used in this work. This study makes use of the following ALMA data numbers: 2011.0.00007.SV, 2012.1.00712.S, 2013.1.00018.S, 2013.1.00061.S, 2013.1.00278.S, 2013.1.00352.S, and 2015.1.01193.S. ALMA is a partnership of ESO (representing its member states), NSF (United States), and NINS (Japan), together with NRC (Canada), MOST and ASIAA (Taiwan), and KASI (Republic of Korea), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO, and NAOJ. This work has been partially supported by MINECO and FEDER (project numbers ESP2015-65597-C4-1, CTQ2017-89150-R, and ESP2017-86582-C4-1-R), and by the Spanish State Research Agency (AEI) through project number MDM-2017-0737 Unidad de Excelencia "Maria de Maeztu"- Centro de Astrobiologia (INTA-CSIC).Peer reviewMary Ann Liebert PublishersUnidad de Excelencia Científica María de Maeztu Centro de Astrobiología del Instituto Nacional de Técnica Aeroespacial y CSIC, MDM-2017-0737Cocinero, E. J. [0000-0001-7632-3728]Martín Doménech, R. [0000-0001-6496-9791]Gobierno VascoAgencia Estatal de Investigación (AEI)Ministerio de Economía y Competitividad (MINECO)202120212020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501application/pdfhttps://www.liebertpub.com/doi/10.1089/ast.2019.2125http://hdl.handle.net/20.500.12666/270reponame:DIGITAL.INTA Repositorio Digital del Instituto Nacional de Técnica Aeroespacialinstname:Instituto Nacional de Técnica Aeroespacial (INTA)InglésCONTRIBUCION ESPAÑOLA A LAS MISIONES ESPACIALES CRIOGENICAS SPICA Y ATHENA, POST-OPERACIONES DE HERSCHEL Y EXPLOTACION CIENTIFICA MULTIFRECUENCIAinfo:eu-repo/grantAgreement/MINECO//ESP2015-65597-C4-1-RMETODOS ESTRUCTURALES DE DISEÑO DE GLICOPEPTIDOS PARA VACUNAS ANTICANCERIGENASCONTRIBUCION ESPAÑOLA EN CRIOGENIA A MISIONES ESPACIALES: DESARROLLOS PARA SPICA Y ATHENA, POST-OPERACIONES DE HERSCHEL Y EXPLOTACION CIENTIFICA MULTIFRECUENCIAinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2017-89150-Rinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/ESP2017-86582-C4-1-RAttribution-NonCommercial-NoDerivatives 4.0 InternationalCopyright 2020, Mary Ann Liebert, Inc., publishershttps://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:digital.inta.es:20.500.12666/2702026-06-23T12:46:37Z
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