Widespread Circulation of Flaviviruses in Horses and Birds in Northeastern Spain (Catalonia) between 2010 and 2019

The surveillance for West Nile virus (WNV) in Catalonia (northeastern Spain) has consistently detected flaviviruses not identified as WNV. With the aim of characterizing the flaviviruses circulating in Catalonia, serum samples from birds and horses collected between 2010 and 2019 and positive by pan...

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Detalles Bibliográficos
Autores: Napp Avelli, Sebastián|||0000-0001-5813-7286, Llorente, Francisco|||0000-0003-1566-0266, Beck, Cécile|||0000-0002-9053-1416, José Cunilleras, Eduard|||0000-0002-4536-7717, Soler, Mercè, Pailler-García, Lola|||0000-0003-1211-7057, Amaral, Rayane, Aguilera-Sepúlveda, Pilar|||0000-0002-2587-528X, Pifarré, Maria, Molina López, Rafael|||0000-0002-9043-2346, Obón, Elena|||0000-0003-4228-717X, Nicolás, Olga, Lecollinet, Sylvie|||0000-0001-8535-2133, Jiménez-Clavero, Miguel Ángel|||0000-0003-2125-9743, Busquets, Núria|||0000-0001-5246-8260
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:269499
Acceso en línea:https://ddd.uab.cat/record/269499
https://dx.doi.org/urn:doi:10.3390/v13122404
Access Level:acceso abierto
Palabra clave:West Nile virus
Usutu virus
Bagaza virus
Tick-borne encephalitis virus
Flaviviruses
Spain
Descripción
Sumario:The surveillance for West Nile virus (WNV) in Catalonia (northeastern Spain) has consistently detected flaviviruses not identified as WNV. With the aim of characterizing the flaviviruses circulating in Catalonia, serum samples from birds and horses collected between 2010 and 2019 and positive by panflavivirus competition ELISA (cELISA) were analyzed by microneutralization test (MNT) against different flaviviruses. A third of the samples tested were inconclusive by MNT, highlighting the limitations of current diagnostic techniques. Our results evidenced the widespread circulation of flaviviruses, in particular WNV, but also Usutu virus (USUV), and suggest that chicken and horses could serve as sentinels for both viruses. In several regions, WNV and USUV overlapped, but no significant geographical aggregation was observed. Bagaza virus (BAGV) was not detected in birds, while positivity to tick-borne encephalitis virus (TBEV) was sporadically detected in horses although no endemic foci were observed. So far, no human infections by WNV, USUV, or TBEV have been reported in Catalonia. However, these zoonotic flaviviruses need to be kept under surveillance, ideally within a One Health framework.

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