Evolutionary and functional analyses of LRP5 in archaic and extant modern humans
[Background] The human lineage has undergone a postcranial skeleton gracilization (i.e. lower bone mass and strength relative to body size) compared to other primates and archaic populations such as the Neanderthals. This gracilization has been traditionally explained by differences in the mechanica...
| Autores: | , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/372299 |
| Acceso en línea: | http://hdl.handle.net/10261/372299 https://api.elsevier.com/content/abstract/scopus_id/85194519974 |
| Access Level: | acceso abierto |
| Palabra clave: | Neanderthal LRP5 Archaic introgression Bone mineral density Denisovan Human evolution |
| Sumario: | [Background] The human lineage has undergone a postcranial skeleton gracilization (i.e. lower bone mass and strength relative to body size) compared to other primates and archaic populations such as the Neanderthals. This gracilization has been traditionally explained by differences in the mechanical load that our ancestors exercised. However, there is growing evidence that gracilization could also be genetically influenced. |
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