Exploring the influence and identifying key predictors of sleep difficulties on health status in long-term breast cancer survivors: A cross-sectional study

Abstract Purpose: This study analyzed the relationship between different levels of sleep difficulties and physical, mental, and emotional variables in long-term breast cancer survivors (LTBCSs), and identified predictors of sleep-related complaints. Methods: Eighty LTBCSs participated in this cross-...

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Detalles Bibliográficos
Autores: Álvarez-Salvago, Francisco, Pujol-Fuentes, Clara, Figueroa-Mayordomo, Maria, Molina-García, Cristina, Atienzar-Aroca, Sandra, Jiménez-García, José Daniel, Estornut, Cristina, Gutiérrez-García, Palmira, Medina-Luque, Jose
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Ajuntament de Barcelona
Repositorio:RUJA. Repositorio Institucional de la Producción Científica de la Universidad de Jaén
OAI Identifier:oai:dnet:ruja________::2031469a4b8b1a43b9e6541ec35e6a55
Acceso en línea:https://hdl.handle.net/10953/7776
Access Level:acceso abierto
Palabra clave:Breast cancer
Health-related quality of life
Long-term survivorship
Physical activity
Sleep disturbances
616-006.04:618.19-036.8:613.79:613.98
Descripción
Sumario:Abstract Purpose: This study analyzed the relationship between different levels of sleep difficulties and physical, mental, and emotional variables in long-term breast cancer survivors (LTBCSs), and identified predictors of sleep-related complaints. Methods: Eighty LTBCSs participated in this cross-sectional study. Sleep difficulties were assessed via item 11 of the EORTC QLQ-C30, classifying participants into two groups: low (n = 44; ≤ 26.29) and high sleep difficulties (n = 36; ≥ 26.30). Additional measures included the EORTC QLQ-BR23, Piper Fatigue Scale, Visual Analog Scale, Brief Pain Inventory, International Fitness Scale, Minnesota Leisure Time Physical Activity questionnaire, and the Scale for Mood Assessment. Statistical analyses comprised ANOVA, Mann-Whitney U, Chi-square, correlation, and multiple regression; effect sizes were calculated using Cohen's d. Results: Fifty-five percent of LTBCSs reported higher sleep difficulties. This group showed greater physical, mental, and emotional impairments, including cancer-related fatigue (CRF), pain, lower self-perceived fitness, reduced physical activity (PA), worse mood, and diminished health-related quality of life (HRQoL) (all p < 0.05). Regression identified "role functioning" (β = -0.37; p < 0.01), "nausea and vomiting" (β = 0.37; p < 0.01), and "PA level" (β = -0.17; p = 0.02) as significant predictors of higher levels of sleep difficulties (adjusted r2 = 0.58). Conclusion: Five or more years post-diagnosis, 55% of LTBCSs experienced higher sleep difficulties, associated with poorer HRQoL, self-perceived physical fitness, mood, and increased CRF and pain. Key predictors explained 58.4% of variance in sleep difficulties. Keywords: Breast cancer; Health-related quality of life; Long-term survivorship; Physical activity; Sleep disturbances.