Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery

In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loade...

Full description

Bibliographic Details
Authors: Estelrich i Latràs, Joan, Escribano Ferrer, Elvira, Queralt i Regué, Josep, Busquets i Viñas, Ma. Antonia
Format: article
Status:Published version
Publication Date:2015
Country:España
Institution:Universidad de Barcelona
Repository:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/149424
Online Access:https://hdl.handle.net/2445/149424
Access Level:Open access
Keyword:Nanopartícules
Liposomes
Quimioteràpia
Òxid de ferro
Nanoparticles
Chemotherapy
Ferric oxide
id ES_1e2b4f55839f4b3014635b74cf1ff72f
oai_identifier_str oai:diposit.ub.edu:2445/149424
network_acronym_str ES
network_name_str España
repository_id_str
spelling Iron oxide nanoparticles for magnetically guided and magnetically responsive drug deliveryEstelrich i Latràs, JoanEscribano Ferrer, ElviraQueralt i Regué, JosepBusquets i Viñas, Ma. AntoniaNanopartículesLiposomesQuimioteràpiaÒxid de ferroNanoparticlesLiposomesChemotherapyFerric oxideIn this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loaded with drugs to a specific site within the body or to increase the transfection capacity. Magnetofection is the delivery of nucleic acids under the influence of a magnetic field acting on nucleic acid vectors that are associated with magnetic nanoparticles. In magnetically-responsive nanoparticles, magnetic nanoparticles are encapsulated or embedded in a larger colloidal structure that carries a drug. In this last case, an alternating magnetic field can modify the structure of the colloid, thereby providing spatial and temporal control over drug release.MDPI2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/149424Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.3390/ijms16048070International Journal of Molecular Sciences, 2015, vol. 16, num. 4, p. 8070-8101https://doi.org/10.3390/ijms16048070cc-by (c) Estelrich i Latràs, Joan et al., 2015http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1494242026-05-27T06:46:51Z
dc.title.none.fl_str_mv Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
title Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
spellingShingle Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
Estelrich i Latràs, Joan
Nanopartícules
Liposomes
Quimioteràpia
Òxid de ferro
Nanoparticles
Liposomes
Chemotherapy
Ferric oxide
title_short Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
title_full Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
title_fullStr Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
title_full_unstemmed Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
title_sort Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
dc.creator.none.fl_str_mv Estelrich i Latràs, Joan
Escribano Ferrer, Elvira
Queralt i Regué, Josep
Busquets i Viñas, Ma. Antonia
author Estelrich i Latràs, Joan
author_facet Estelrich i Latràs, Joan
Escribano Ferrer, Elvira
Queralt i Regué, Josep
Busquets i Viñas, Ma. Antonia
author_role author
author2 Escribano Ferrer, Elvira
Queralt i Regué, Josep
Busquets i Viñas, Ma. Antonia
author2_role author
author
author
dc.subject.none.fl_str_mv Nanopartícules
Liposomes
Quimioteràpia
Òxid de ferro
Nanoparticles
Liposomes
Chemotherapy
Ferric oxide
topic Nanopartícules
Liposomes
Quimioteràpia
Òxid de ferro
Nanoparticles
Liposomes
Chemotherapy
Ferric oxide
description In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loaded with drugs to a specific site within the body or to increase the transfection capacity. Magnetofection is the delivery of nucleic acids under the influence of a magnetic field acting on nucleic acid vectors that are associated with magnetic nanoparticles. In magnetically-responsive nanoparticles, magnetic nanoparticles are encapsulated or embedded in a larger colloidal structure that carries a drug. In this last case, an alternating magnetic field can modify the structure of the colloid, thereby providing spatial and temporal control over drug release.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/149424
url https://hdl.handle.net/2445/149424
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/ijms16048070
International Journal of Molecular Sciences, 2015, vol. 16, num. 4, p. 8070-8101
https://doi.org/10.3390/ijms16048070
dc.rights.none.fl_str_mv cc-by (c) Estelrich i Latràs, Joan et al., 2015
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Estelrich i Latràs, Joan et al., 2015
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869404321036107776
score 15,300719