Spectrum of Headaches Associated With SARS‐CoV‐2 Infection: Study of Healthcare Professionals

Background: Series of patients with SARS‐CoV‐2 infection report headache in 6%‐15% of cases, although some data suggest that the actual frequency is higher, and that headache is not associated with fever. No study published to date has analyzed the characteristics of headache in these patients. Obje...

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Detalles Bibliográficos
Autores: Porta Etessam, Mariano Jesús, Matias Guiu, Jordi A., González García, Nuria, Gómez Iglesias, Patricia, Santos Bueso, Enrique, Arriola Villalobos, Pedro, García Azorín, David, Matías-Guiu Guía, Jorge
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/6467
Acceso en línea:https://hdl.handle.net/20.500.14352/6467
Access Level:acceso abierto
Palabra clave:616.857
616.98:578.834
578.834:616.98
COVID-19
SARS-CoV-2
Headache
Migraine
Neurological symptoms
Healthcare professionals
Enfermedades infecciosas
Neurociencias (Medicina)
Oftalmología
3205.05 Enfermedades Infecciosas
2490 Neurociencias
3201.09 Oftalmología
Descripción
Sumario:Background: Series of patients with SARS‐CoV‐2 infection report headache in 6%‐15% of cases, although some data suggest that the actual frequency is higher, and that headache is not associated with fever. No study published to date has analyzed the characteristics of headache in these patients. Objective: To analyze the characteristics of COVID‐19 related headaches. Methods: We conducted a survey of Spaniard healthcare professionals who have been infected by SARS‐CoV‐2 and presented headache during the course of the disease. The survey addressed respondents’ medical history and headache characteristics, and we analyzed the association between both. Results: We analyzed the responses of a sample of 112 healthcare professionals. History of migraine was reported by 20/112 (17.9%) of respondents, history of tension‐type headache by 8/112 (7.1%), and history of cluster headache was reported by a single respondent; 82/112(73.2%) of respondents had no history of headache. Headache presented independently of fever, around the third day after symptom onset. The previous history of migraine was associated with a higher frequency of pulsating headache (20% in patients with previous migraine vs 4.3% in those with no history of migraine, P = .013). Conclusion: Headache is often holocranial, hemicranial, or occipital, pressing, and worsens with physical activity or head movements. Because the characteristics of the headache and the associated symptoms are heterogeneous in our survey, we suggest that several patterns with specific pathophysiological mechanisms may underlie the headache associated with COVID‐19.